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J C Baste

Publications and source records attributed to J C Baste.

54 records · Page 3Linked to original sources

[Study of the efficacy and tolerance of imipenem-cilastatin used as monotherapy for the adjuvant treatment to surgery of peritonitis. Results of a French multicenter study including 257 patients].

The antibiotic treatment of peritonitis classically resorts to the association of two and even three molecules. In order to test the efficacy of a single-drug therapy with Tienam* imipenem/cilastatin) as an adjunctive treatment associated to surgery for perforation peritonitis, an open, non-comparative study of 257 patients was carried out in 28 departments. Imipenem is the first beta-lactam antibiotic of the carbapenem family. This antibiotic seems to be particularly useful for the treatment of mixed polymicrobial infections such as peritoneal infections, owing to its activity spectrum covering Gram-positive and Gram-negative, aerobic and anaerobic germs, including strands with multiple resistances (Enterobacter, Pseudomonas aeruginosa, Serratia marcescens, Acinetobacter, Enterococcus and Bacteroides fragilis). A total of 212 patients were assessed with a treatment averaging 7 days. The five most frequently isolated bacteria were Escherichia coli, streptococci, Bacteroides, Proteus and Klebsiella. The healing or improvement rate was 95.3% (202/212). Seven cross-infections occurred during of after the treatment. Tolerance is good in 96% of all cases. Adverse effects were infrequent and mild: the hepatic and hematological alterations never required the interruption of the treatment and they were reversible; the treatment was interrupted in one patient only because of omental tremulation.

Adolescent↗

[Endoluminal angioplasty of the superior mesenteric artery in the treatment of intestinal angina].

The authors report about the case of a 69-year-old patient suffering from intestinal angina, in whom an endoluminal angioplasty of the superior mesenteric artery for a stenosis located 3 cm from the ostium allowed suppressing the symptoms. The published series of arterial angioplasty for gastrointestinal care are still rare, but they indicate that angioplasty may be an interesting alternative to or a complement to surgery for patients with intestinal angina.

Aged↗

[Peritoneal complications during continuous ambulatory peritoneal dialysis: surgical aspects].

The principal complication of continuous ambulatory peritoneal dialysis (CAPD) is peritonitis in most cases benign and treated effectively by local, specific antibiotic therapy. In some cases, however, the infection fails to respond to medical treatment and surgical exploration occasionally reveals serious lesions such as sclerosing peritonitis or an intestinal perforation. Prognosis is dependent not only on the extent and severity of the lesion but also on the rapidity of operative intervention. The development of an appendicitis, often masked by early antibiotic therapy, represents a particular course of peritoneal infection during CAPD.

Adolescent↗

[Chronic course of rupture of subrenal aortic aneurysms. Apropos of two cases].

We report two new cases of aneurysms of the sub-renal aorta in which rupture was followed by a chronic clinical course. In the first, there was an atheromatous aneurysm which led to chronic lombo-sciatic pain over a period of 15 months before exact diagnosis. The second concerned an aneurysm probably related to Yersinia enterolitica infection which led to abdominal pain over a period of 3 weeks. In both cases, the diagnosis was made on the CT scan and the operation led to the immediate disappearance of the symptomatology. Although a particular entity of sub-renal aorta aneurysms is still under debate, identifying an identifiable subset appears to be justified. Indeed, cases in which a chronic course follows rupture have particular characteristics including the absence of effect on general haemodynamics and an operative risk identical to nonruptured aneurysms. These characteristics differentiate this subset from non-sealed retroperitoneal aneurysms of the aorta.

Aged↗