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J C Berthier

Publications and source records attributed to J C Berthier.

47 records · Page 3Linked to original sources

Otoacoustic emissions and brainstem auditory evoked potentials in children with neurological afflictions.

Findings are reported for evoked otoacoustic emissions (EOAEs) recorded from 22 children with neurological afflictions, whose brainstem auditory evoked potentials (BAEPs) were pathological on at least one side (41 ears explored). Our results confirmed that EOAEs are always present in children and infants having normal BAEPs. Absence of EOAE (n = 22) was almost always related to middle ear or cochlear damage with BAEPs indicating diagnoses, respectively, of transmission damage (n = 7) or endocochlear damage (n = 16). Conversely, for BAEP diagnoses of retrocochlear damage (n = 12), EOAEs were always present. EOAEs associated with BAEPs, therefore, appear to offer a well-adapted technique for precise etiological diagnosis of childhood hearing loss. When no wave is identifiable by BAEP recording, EOAE presence indicates retrocochlear damage.

Child↗

[Acquired neonatal herpes].

The authors report a case of neonatal herpes simplex infection with favourable outcome, without any sign of meningo-encephalitis or dissemination. The child was given antiviral treatment with Acyclovir from the first day of rash. Vesicle scraping and a complete serologic study of both child and mother proved infection was due to herpes simplex virus type I, transmitted to the neonate during primary maternal infection with gingivostomatitis beginning on the day of delivery. The different routes of postnatal contamination of the neonate by herpes virus and the risks of dissemination are reviewed. The importance of preventing contamination and dissemination of a known herpetic infection in maternity-hospitals and in nurseries for newborns is emphasized. Antiviral treatment should be used in all neonates with localized herpetic infection.

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[Colchicine poisoning apropos of a pediatric case].

Colchicine has been widely used in the treatment of gout and familial mediterranean fever. Overdose is rare mostly in childhood. Colchicine overdose always causes gastrointestinal side effects, bone marrow depression and sometimes neuropathy. The mechanism of colchicine upon the microtubules, provides a better understanding of the pharmacology and also of the multiorgan involvement. We report the case of a ten year old child who ingested 0.6 mg/kg colchicine with a good outcome.

Child↗