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Biomedical subjects

J C Clay

Publications and source records attributed to J C Clay.

At least 19 recordsLinked to original sources

Influence of management system on litter size, lamb growth, and carcass characteristics in sheep.

Three management systems (winter, spring, and late summer) distinguished by season of lambing and management practices were compared for litter size born and weaned and growth and carcass characteristics of lambs. Three sire breeds (Cheviot, Rambouillet, and Suffolk) and three dam breeds (Florida Native, Native-X, and Synthetic-X) were used in 698 matings over a 3-yr period. System affected (P < .01) litter size born. Spring lambing yielded more lambs (1.62) than winter (1.49) and late summer (1.12). The winter-born lambs were lighter but fatter (P < .05), and spring-born lambs were leaner with higher leg conformation and carcass quality scores. The late summer-born lambs were not different from spring-born lambs. Wethers had higher (P < .01) weights off test than ewe lambs (43.9 vs 42 kg) but had lower (P < .01) leg conformation scores, percentage kidney and pelvic fat, yield grade, and dressing percentages. Dam breed effects were significant (P < .05) for average preweaning daily gains with 249+/-5, 201+/-9, and 191+/-9 g for progeny of Native-X, Florida Native, and Synthetic-X, respectively. Single-born lambs had higher daily gains (P < .05) than twins in a preweaning period in all management systems and higher postweaning and lifetime daily gains for winter and spring management systems.

Animal Husbandry↗

Impact of socioeconomic status on health care utilization: factors influencing length of stay.

Using multivariate analysis, this study evaluates the relationship between socioeconomic status and hospital resource utilization as measured by length of stay for elderly Medicare patients, age 65 and older, within Shelby County, Tennessee. Variations in length of stay are compared across income groupings for seven different Diagnosis Related Groups (DRGs) and relative effects are measured for socioeconomic status, age, race, gender, discharge status, and severity of illness. Despite the lack of provider specific and patient specific information, the analysis does suggest that, once patients access the medical care system, socioeconomic status has a limited effect on discharge decisions. The results also indicate that the effect of administratively necessary days on length of stay needs further policy review.

Aged↗

Patient and family education: an interdisciplinary process.

An interdisciplinary education and discharge plan was developed in a 404-bed teaching hospital to coordinate and integrate the function of patient and family education across disciplines using one common form. This education plan was instrumental in providing improved documentation of patient and family education in both inpatient and outpatient departments.

Family↗

Beef Quality Assurance education via satellite videoconference.

A 1.5-h satellite video program was developed for a statewide Beef Quality Assurance (BQA) producer education activity. Twenty-seven downlink sites were identified across the state, and additional known downlink sites included one each in Minnesota, Indiana, and Monterrey, Mexico. The videoconference was formally evaluated by viewers and resource people at each site. Program participants included representatives of the Ohio and National Cattlemen's Associations and two producers currently implementing BQA programs. A toll-free telephone number was available for viewer's questions during the last 15 min of air time and following the video program. A demographic data form and pre- and postconference evaluations were completed by 368 participants. Twenty-seven percent of the respondents were age 56 or older; 76% were age 36 or older. A one to five scale (strongly disagree to strongly agree) was used for evaluation. Beef Quality Assurance was considered by viewers to be an important consideration for the future in pre- (mean = 4.5, SD = .99) and post-evaluations (mean = 4.6, SD = .83). The mean response to the question regarding using more videoconferencing for agriculture programming was 3.9 (SD = .91). Four percent of participants indicated less or no videoconferencing should be used, 24% were neutral, and 72% felt more videoconferencing should be done. Comments were neutral with regard to the length of the conference (mean = 3.5, SD = .86) and the complexity of the subject matter (mean = 3.1, SD = .64). More than 88% of the participants agreed or strongly agreed that they intended to examine their overall production strategies to see where they could improve the quality of beef they produce (mean = 4.3, SD = .85). After the videoconference, 2.6% of respondents still strongly believed that BQA was not an important consideration for the future of the beef industry. The cost of all activities associated with this satellite video program was $13,000.

Adult↗

Evaluation of a novel solid-phase immunoassay, Clearview Chlamydia, for the rapid detection of Chlamydia trachomatis.

Clearview Chlamydia (Unipath Limited, Bedford, United Kingdom) is a rapid immunoassay for the direct detection of Chlamydia trachomatis antigen. This assay was evaluated against the tissue culture method by using 376 paired endocervical specimens. The Clearview assay had a sensitivity of 93.5% and a specificity of 99% when it was compared with the tissue culture method. This assay does not require specialized equipment or trained personnel and yields results within 30 min from the time that a specimen is collected.

Bacteriological Techniques↗

Efficacy of ceftizoxime in the treatment of uncomplicated gonorrhoea: comparison with amoxycillin.

Four centres contributed a total of 466 patients to a study comparing the efficacy of oral amoxycillin with that of probenecid and intramuscular ceftizoxime. Both treatments were equally efficacious, except in the small number of penicillinase-producing Neisseria gonorrhoeae patients, all of whom responded to ceftizoxime and none to amoxycyllin. Both treatments were well tolerated, the only two adverse effects occurring in the ceftizoxime group.

Adolescent↗

Practical problems of diagnosing trichomoniasis in women.

Analysis of eight groups of data collected at varying intervals during a period of seven years showed fluctuations in the sensitivity of tests to diagnose trichomoniasis in women. The best results were obtained from fresh, correctly prepared Diamond's medium, Feinberg-Whittington's medium, and modified Squires and McFadzean's medium (which showed 82% to 94% relative sensitivity). Poor results were identified consistently in commercially prepared Bushby medium from one source (40% relative sensitivity) and in a batch of commercially prepared Squires and McFadzean's medium from which chloramphenicol had been omitted (23% relative sensitivity). Examination of wet film, culture, and exfoliative cytology stained by Papanicolaou's method were shown to be indispensable for auditing the performance of each test and to maintain the quality of a diagnostic service.

Animals↗

Patterns of psychiatric morbidity in a genito-urinary clinic. A validation of the Hospital Anxiety Depression scale (HAD).

The prevalence of psychiatric disorder (by DSM-III criteria) in a population attending a genito-urinary clinic was found to be 31%. The performance of the Hospital Anxiety Depression (HAD) scale as a screening questionnaire for psychiatric disorder was assessed. Case definition by a score of 8 or more on either of the anxiety or depressive subscales produced optimal results, giving sensitivities of 82% and 70%, and specificities of 94% and 68%, for depressive and anxiety disorders respectively.

Adult↗

Neonatal herpes.

Explore the source record for details and available documents.

Cervix Uteri↗

Pooled specimens for Chlamydia trachomatis: new approach to increase yield and cost efficiency.

Pooled specimens from the urethra and cervix accounted for 97% of 101 positive chlamydial isolations in 332 women, and this yield compared favourably with the individual yield from either the urethra (77%) or the cervix (88%). Pooling specimens caused no apparent increase in toxicity to the cell culture system. These results indicate the advantages, in terms of higher yield and no higher cost, of combining the urethral and cervical specimens in one container.

Cervix Uteri↗

Penicillinase producing strains of Neisseria gonorrhoeae in the West Midlands 1979-83.

All cases of gonorrhoea caused by penicillinase producing strains of Neisseria gonorrhoeae (PPNG) occurring in the population served by the West Midlands Regional Health Authority were surveyed. Isolates that were subjected to plasmid analysis were found to be mainly the "Asian" type in travellers from abroad and their immediate contacts, whereas isolates apparently indigenous in origin were mainly "African" type. The emerging sigmoid curve of yearly incidence, which is apparent for both the country and the region, may indicate that a dynamic equilibrium is being approached in the susceptible core populations. The importance of vigorous contact tracing is underlined by the contrast between the incidence of PPNG strains in the United Kingdom and the larger numbers found in areas where they are hyperendemic and where contact tracing is ineffectual or non-existent.

Adult↗

Induction by human serum of resistance to serum in Neisseria gonorrhoeae: A clinical survey of patients with gonorrhoea.

Serum from 74 female and 170 male patients with gonorrhoea and from 72 male and 123 female controls was tested for its ability to induce in gonococci resistance to complement mediated killing by human serum. We confirmed two findings of a previous survey: firstly, a higher percentage of serum samples from women suffering their first infection than from female controls induced high resistance; secondly, no serum sample taken from infected women with complications (mainly salpingitis) induced high resistance. The number of serum samples from female patients with repeat infection was too small for conclusions to be drawn. In men, however, there were no significant differences between patients and controls, or between patients with first or repeat infection, in the percentage whose serum induced high resistance. The pattern of these results on the induction of resistance to serum correlates with the general clinical aspects of gonococcal infections; namely, wide clinical differences in symptoms in women contrasting with a more uniform pattern in men.

Blood Bactericidal Activity↗

Efficacy of vaccine Ac NFU1 (S-) MRC 5 given after an initial clinical episode in the prevention of herpes genitalis.

A subunit antigenoid vaccine, Ac NFU1 (S-) MRC 5, was used in patients who had had a clinical episode of herpes genitalis. The rate of recurrence was compared with that in unvaccinated patients to determine the efficacy of vaccination in preventing recurrence and spread of the virus in the community. Seven of 22 (31%) vaccinated patients had eight recurrences after the initial clinical episode; in contrast there were 51 recurrences in 17 of 20 (85%) unvaccinated patients. Although further studies are needed, the results indicate that the vaccine may prevent recurrent episodes of herpes genitalis and thereby reduce the dissemination of this virus in the population.

Adolescent↗