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J C Corredoira

Publications and source records attributed to J C Corredoira.

9 recordsLinked to original sources
PubMed2000

[Fulminant streptococcus infection of soft tissue].

BACKGROUND: In recent years there has been an apparent increase in severe infections produced by group A beta-hemolytic Streptococci in developed countries. Necrotizing fascitis and myositis are two rare but fearsome complications caused by this microorganism. METHODS: Two cases of fulminant soft tissue infection recently observed in the authors' center are presented and the clinical presentation and differential diagnosis commented upon. RESULTS: The first case was a necrotizing fascitis at a surgical wound which appeared following a gynecological surgery. The second case reports gluteal myositis following intramuscular injection. In both cases the evolution was disastrous. CONCLUSIONS: Streptococcus pyogenes may produce fulminant infections in patients without underlying disease either spontaneously or following minimum traumas. The most frequent involvement is of the soft tissues. This virulence at a local tissue and systemic level has been associated with the production of exotoxin.

Diagnosis, Differential↗
PubMed1996

Prospective study of Streptococcus milleri bacteremia.

In a prospective study of bacteremia caused by organisms of the Streptococcus milleri group a total of 32 adult patients were observed over a seven-year period. These patients accounted for 1.6% of all patients diagnosed as having significant bacteremia and 17% of all cases of streptococcal (nonpneumococcal) bacteremia diagnosed during the study period. Only five patients had polymicrobic bacteremia. In 31 cases, a presumed origin of infection was identified, generally oral or gastrointestinal disease. There were only six cases of nosocomial acquisition. The most common presenting symptom was prolonged fever. The following forms of presentation were documented: bacteremia with local suppurative infection (56%), bacteremia without local suppurative infection (25%), and endocarditis (19%). An associated focus of infection was found in the abdominal cavity in 20 cases (62%). The mortality rate was 12.5%. All isolates were susceptible to penicillin. Caution is necessary in interpreting a blood culture positive for Streptococcus milleri group organisms, since, unlike other viridans streptococci, they are rarely contaminants. For this reason patients with suppurative processes and/or digestive tract disease must be carefully investigated.

Adult↗
PubMed1993

[Common variable immunodeficiency and polyarthritis: a case report].

We describe a man with common variable immunodeficiency and polyarthritis. He had suffered several infections, including septic arthritis. For this reason we commenced treatment with antibiotics without obtaining a good response. Three weeks' later, and after knowing that the results of all the cultures were negative, we discontinued the antibiotic therapy and started treatment with indomethacin. A dramatic response was rapidly observed. We feel that an arthritis in a patient with a history of previous infections should alert us to the diagnostic possibility of primary antibody deficiency.

Adult↗
PubMed1990

[A clinical and biological study of 33 cases of polycythemia vera].

The clinical, analytical, evolutive and therapeutic aspects of 33 cases of polycythemia vera which were diagnosed according to the Polycythemia Vera Study Group criteria, are described. Mean age was 65 years with a slight predominance of females (54.5%). Hemorrhagic manifestations were the most frequent (67%) with a great number of patients with digestive manifestations consisting of GI hemorrhage, abdominal pain, portal or suprahepatic veins thrombosis. Splenomegaly was the most frequently found sign upon examination (73%). The mean hemoglobin leukocyte, and platelet levels were 18 g/dl, 16,000 mm3 and 738,000 mm3 respectively. It is note worthy the value of the erythropoietin for the differential diagnosis of secondary erythrocytosis as well as the value of the bone marrow histologic study which should be included in the diagnostic criteria of the disease. The evolution of the process is favorably altered by bleedings and chemotherapeutic cytoreduction which are often performed simultaneously.

Adult↗
PubMed1989

[A clinical and biological study of 11 cases of essential thrombocythemia].

11 patients diagnosed as suffering from essential thrombocytosis at "Hospital Xeral de Lugo" between 1978 and 1986, are presented. 7 patients were female and 4 were male with a median age of 63 years. 6 patients had thrombotic manifestation, 6 had hemorrhagic symptoms, 2 had both manifestations and only one had no thrombo-hemorrhagic clinical symptoms. Spleen enlargement was found in 6 cases and liver enlargement in 5. The median count of platelets were 1.585.000 ml; there was no relationship between the amount and their function with the major or minor complications incidence. There was a good response to treatment with hydroxyurea and/or busulfan associated to platelets aggregation inhibitor in some cases. 4 patients died, all of them due to thrombotic complications.

Adult↗