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J C Couffinhal

Publications and source records attributed to J C Couffinhal.

26 records · Page 2Linked to original sources
PubMed1980

[Heparin-induced thrombopenia. Vascular complications in six cases (author's transl)].

The most frequent complication during heparin treatment is hemorrhage from overdosage. Heparin-induced thrombopenia is more rarely observed but is a more serious disorder. Six such cases are reported, of which three were complicated by gangrene of the limbs. Clinical findings are described, together with the methods of detecting the presence of heparin-induced antiplatelet antibodies. The affection becomes evident on the 9th day of treatment by the presence of a thrombopenia and accompanying clinical signs. These may be those of a hemorrhagic syndrome directly related to the thrombopenia, or manifestations of thrombotic lesions. The latter can cause worsening of the condition for which heparin was prescribed, arterial thrombosis of a large vessel, venous thromboses disappearing after interruption of heparin treatment, of distal thrombosis of the microcirculation with a rapidly irreversible onset of gangrene requiring amputation. The lesions are provoked by an immune mechanism and heparin has to be discontinued.

Adult↗
PubMed1978

[Renal artery acute thrombosis following abdominal angiography. 3 cases (author's transl)].

Three cases of acute thrombosis of the renal artery following an abdominal angiography were operated on. In each case a tight stenosis of the renal artery was present. Two different clinical features were observed: when the thrombosis occurs in a solitary kidney, anuria follows immediately the angiography and this is highly suggestive of the diagnosis; when the contralateral kidney functions well, the thrombosis, probably, will not be recognized. Treatment should always be surgical. In two cases emergency surgery resulted in kidney salvage, whereas in the last the diagnosis was overlooked and delayed surgery could not avoid nephrectomy. Viability of the kidney may be ensured by the collateral circulation and this fact justifies surgery in all cases.

Adult↗
PubMedDate not supplied

[Mycotic aortic aneurysms (author's transl)].

Mycotic aortic aneurysms were detected in four men aged between 47 and 73 years. The infective nature of the lesion was obvious in one case, while in the other three cases the diagnosis was suspected after radiological examination and confirmed by pathological and bacteriological investigations of the aneurysm wall. Radiological signs which suggest the presence of an infective aneurysm include rupture of the aneurysm, a rapidly progressing course, and unusual locations or morphology. Diagnosis is important as therapy differs from that of other types of aneurysm.

Aged↗