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Biomedical subjects

J C Cutler

Publications and source records attributed to J C Cutler.

14 recordsLinked to original sources
PubMed1981

Venereal disease prevention.

Outlining his interest and work in the prevention of VD, especially gonorrhea and syphilis, the author addresses the questions of prophylaxis and contraceptives, together with their technological advances, and ties these two concepts into the complex fabric of human behavior, history of available therapy in both world wars as well as the economic, social, moral and national concepts of what constitutes proper emphasis: prevention or cure. Thus, the absence of therapeutic modalities spurred the United States Armed Services to utilize Credé's solution for urethral irrigation and locally applied calomel ointment for prophylactic purposes in World War I but abandoned this mode when cheap penicillin therapy became available after World War II. Similarly, the utilization of combined prophylactic and contraceptive methods for women has to await the overcoming of societal and parental resistance. Particularly where teenagers are concerned the importance of combined modalities is stressed.

Adolescent↗
PubMed1976

Virucidal effect of certain chemical contraceptives on Type 2 herpesvirus.

The virucidal effect of several chemical contraceptives was investigated and the findings are rrported. The supension of Type 2 herpes simplex virus, containing 10(6) to 10(7) tissue culture infectious doses per 0.1 ml., was inactivated on exposure to five different chemical contraceptives. For quantitative estimates of virucidal effect, 10 per cent solutions of these chemical contraceptives were tested with an exposure time of 10 minutes at room temperature. The methods for determination of residual infectivity included both virus assays in cultures of Vero cells and human embryo fibroblasts, as well as the intracranial inoculation of mice. Virus infectivity decreased 1,000- to 10,000-fold after contact with chemical contraceptives, indicating a substantial virucidal effect.

Animals↗
PubMed1976

The effect of vaginal lubricants on Neisseria gonorrhoeae.

The possible interference of vaginal lubricants in culture diagnosis of gonorrhea was investigated by studying in vitro effect of selected lubricants on Neisseria gonorrhoeae. Two lubricants widely used in family planning and other clinics were demonstrated to have a bactericidal effect on N. gonorrhoeae when tested with more than one method. Gonococci were killed on contact with Lubrifoam, even at a 10 per cent concentration, and an exposure time as short as one minute was sufficient to inhibit the growth on chocolate agar medium. The K-Y jelly showed less inhibitory effect than Lubrifoam. These findings suggest that certain vaginal lubricants have bactericidal effects and their presence can inhibit the growth of Neisseria gonorrhoeae.

Neisseria gonorrhoeae↗