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Biomedical subjects

J C Debrie

Publications and source records attributed to J C Debrie.

At least 19 recordsLinked to original sources

[Endonasal rhinosporidiosis (apropos of 2 cases observed in Gabon)].

Being endemic in India and Sri Lanka, rhinosporidiosis is not much known in Africa where only few cases have been reported for the last 20 years. It is a chronic mycosis striking electively two target zones: nasal and conjunctival mucosae. Many features are still unknown about this pathogenic agent which belongs to the group of phycomycetes. But it has never been yet possible to cultivate it nor to inoculate it to animals. It has a cyclic development, well described by Ashworth. Its treatment is both surgical and medical (fungicides).

Biopsy↗

[Fungal otitis in Libreville. Study of 83 cases].

83 cases of mycotic otitis of external ear are reported during a period of 27 months from three departments of otorhinolaryngology in Libreville (Gabon, Central Africa) Prevalence is estimated at about 25% among all infectious otitis. The main functional signs are pruritus, otorrhea, pain and hypoacousia. The physical examination shows masse of white, grey, black or creamy caseous debris, invading the external auditory meatus (EAM) which is sometimes inflammatory. Fungal species responsible of otitis are Aspergillus (54%), yeasts (45%) mainly Candida, infrequently Fusarium (1%). A niger (26%), A. flavus (17%), Candida parapilosis (18%), Candida albicans (9%) are predominant species isolated (70%) among all the 21 species of identified fungi from otomycosis in Gabon. Therapy, done by thorough washing of the ear followed by insertion into the EAM of a wick soaked in Econazole or Amphotericin B, is quickly effective.

Administration, Topical↗

[Human coenurosis. Localization to the sternocleidomastoid muscle].

Coenurosis, a parasitic affection rarely observed in man, is due to the presence in the tissues of larval forms of Taenias that live in certain domestic or wild carnivorous animals during their adult stage. The disease was confirmed in a young Senegalese patient after surgical excision of a cyst from the lateral side of the neck. Pathological and epidemiological data suggest that the affection is due to Taenia serialis serialis.

Adolescent↗