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J C Dosch

Publications and source records attributed to J C Dosch.

30 records · Page 2Linked to original sources

[Radiological aspects of cerebral and spinal cysticercosis. Apropos of 2 cases].

Two cases of neurocysticercosis are reported, one cerebral and the other spinal. Results of radiologic imaging of this affection, a rare parasitosis in occidental Europe, are discussed with emphasis on computed tomography findings. In fact, when perfect conditions can be established the CT scan provides data confirming the diagnosis of cerebral cysticercosis in most cases. However, this scan is insufficient for investigation of ventricular or cisternal forms when gas or positive contrast is sometimes necessary for visualization of parasitic cysts. Radiologic diagnosis of extra- and intra-medullary forms is based an myelography with water-soluble contrast completed by a scan.

Acute Disease↗

[Axial osteomalacia. Comparative analysis with fibrogenesis imperfecta ossium (author's transl)].

Axial osteomalacia is an infrequent osseous disease, etiopathogeny of which is yet unknown. The authors report three cases of such affection and two cases of fibrogenesis imperfecta ossium. They stress the clinical, biological and radiological specific signs of these diseases. Biopsy is necessary for diagnose some doubtful cases, especially in order to exclude other causes of osteomalacia as fibrogenesis imperfecta ossium. The latter osteopathy which frequency may be underestimated has often similar radiological data.

Aged↗

Automated assay of gamma-aminobutyric acid in human cerebrospinal fluid.

We describe an automated amino acid analyzer with fluorescence detection (o-phthalaldehyde) which permits sensitive and rapid determinations of gamma aminobutyric acid in human cerebrospinal fluid. Concentrations as low as 50 nmol/liter can be accurately determined in 100 mul samples at the rate of one sample per hour. Concentrations in untreated cerebrospinal fluid increase rapidly after sampling by lumbar puncture. The concentration in immediately deproteinized samples from 38 patients with intervertebral disc disorders was 220 +/- 81 nmol/liter (mean +/- SD).

Amino Acids↗

[Early radiological assessment of spinal injuries. Indication for additional imaging procedures].

UNLABELLED: The question of the best radiological diagnostic pathway to explore the acute spinal trauma is discussed. METHOD: the current state of knowledge is given, based on bibliography and the authors experience. RESULTS: Standard-radiography allows fast orientation. CT ist the best procedure for high resolution imaging of bony structures and MRI is best suited for soft tissue and medullar lesions. Ligamentous lesions are still explored with functional X-ray studies, but ligament rupture can be visualized directly by MRI. CONCLUSIONS: Standard-radiography must precede all further studies. In patients without neurological deficit: CT is indicated if standard radiography suspects a bony lesion. MRI is indicated, if there is a discrepancy between a normal radiography and severe complaints of the patient. functional radiographies are indicated if ligamentous damage is suspected, but MRI can directly visualize ligament rupture. In patients with a radicular lesion, CT is indicated. In patients with a medullar or central radicular lesion, MRI or Myelo-CT are indicated.

Adult↗

[Blunt injuries of the spleen. What is the role of splenectomy?].

In an exhaustive retrospective study of splenic trauma diagnosed over a 7-year period (1986-1992) in our orthopaedic trauma centre we collected 63 cases. Splenectomy was performed in 25 patients, conservative surgery was performed in 6 and non-surgical conservative therapy was possible in 32. The large percentage of non-surgical cases was possible due to the simple clinical course in cases diagnosed late and because of careful surveillance and the precision of scanographic diagnosis. The concept of conservative non-surgical treatment appears to be validated by the lack of mortality and the high success rate (only 3 failures out of 32) in our unselected population which included polytrauma cases and patients of all ages and all types of splenic lesions. Nevertheless, shock resulting from splenic injury. In cases where bleeding is the sign of non-surgical treatment failure and in cases with acquired or induced coagulopathy and a pathological spleen, splenectomy is also indicated. Our results indicate that, when scanographic diagnosis is permanently available and when clinical surveillance is adequate, conservative non-surgical treatment can be proposed in patients with a stable haemodynamic status.

Adult↗