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Biomedical subjects

J C Goslings

Publications and source records attributed to J C Goslings.

16 recordsLinked to original sources

Effect of surgical delay on outcome in hip fracture patients: a retrospective multivariate analysis of 192 patients.

Previous studies have not demonstrated consistent results on the effect of surgical delay on outcome. This study investigated the association between the delay to surgery and the development of postoperative complications, length of hospital stay (LOS) and one-year mortality. Patients that underwent surgery for a hip fracture in a two-year period were included in a retrospective study. Uni- and multivariate regression analysis was performed in 192 hip fracture patients. There was a trend towards fewer postoperative complications (P = 0.064; multivariate regression, MR) and shorter LOS (P = 0.088; MR) in patients with a delay of less than one day to surgery. No association between surgical delay and one-year mortality was found in the population as a whole (P = 0.632; univariate regression, UR). Delay to surgery beyond one day was associated with an increased risk of infectious complications (P = 0.004; MR). In ASA I and II class patients, operation beyond one day from admission was associated with an increased risk of one-year mortality (P = 0.03; MR) and more postoperative infectious complications (P = 0.02; MR). The trends towards fewer complications and shorter LOS suggest that early surgery (within one day from admission) is beneficial for hip fracture patients who are able to undergo an operation.

Aged↗

[Children with blunt trauma to the liver].

In 3 children, 2 boys aged 13 years and an 8-year-old girl, blunt trauma to the liver was diagnosed after a fall. The first patient underwent drainage of abdominal fluid collection on multiple occasions and a stent was introduced in the biliary duct to ensure normal bile flow; the second patient was treated by arterial catheter embolisation of a segmental branch of the right hepatic artery; in the third patient, acute laparotomy was performed in view ofhaemodynamic instability and a large hepatic rupture was treated by packing. All patients recovered successfully. In the paediatric population, blunt trauma to the liver requires a multidisciplinary approach. For haemodynamically stable children, a conservative course can be taken. Arterial embolisation is the treatment of choice if there is a persistent need for volume resuscitation or blood transfusion. In case of massive haemorrhagic shock, the child should undergo laparotomy, and if the bleeding cannot be stopped, the liver should be packed according to damage-control principles.

Accidental Falls↗

In-hospital downgrading of the trauma team: Validation of the Academic Medical Center downgrading criteria.

BACKGROUND: To reduce overtriage of trauma patients while at the same time minimising undertriage, an in-hospital triage tool was developed with the purpose of reducing the initial full trauma team (downgrading) in a structured and evidence-based manner. This study evaluated the effect on overtriage rates by the AMC downgrading protocol (AMCDP) consisting of 24 criteria scored during the primary survey. PATIENTS AND METHODS: We prospectively investigated if any of the patients treated by the downgraded trauma team (DTT) were undertriaged by the protocol. All patients fulfilling the definition of severely injured (SI) patients but treated by the DTT were deemed undertriaged patients. Overtriage was measured by the percentage of patients treated by a full trauma team (FTT) while not classified as an SI patient. RESULTS: A total of 220 patients were eligible and triaged by the AMCDP. After triage, 95 patients (43%) were treated by the DTT while 125 patients (57%) were treated by the FTT. A total of 66 patients (30%) met one or more of the criteria for an SI patient. None of these patients were treated by the DTT. Of the 125 patients treated by the FTT, 59 patients were not defined as SI. CONCLUSION: For the entire study population no undertriage was found, while implementation of the AMCDP reduced overtriage in the entire study population from 70% to 26.8%. Similar trauma centres can benefit from implementing the AMC downgrading protocol.

Adolescent↗

Conservative treatment for closed fifth (small finger) metacarpal neck fractures.

BACKGROUND: Subcapital fractures of the fifth metacarpal bone, meaning fractures just below the knuckle of the little finger, account for approximately 20% of all hand fractures. Currently, there is no consensus concerning the optimal management of these fractures. Traditionally, treatment consists of closed reduction and external splinting in a neutral position using plaster of Paris (POP), involving the metacarpal joint, the proximal interphalangeal joint and the carpo-metacarpal joint. An alternative treatment strategy is functional treatment using taping or bracing that does not restrict movement. OBJECTIVES: To compare functional treatment with immobilization, and to compare different periods and types of immobilization, for the treatment of closed fifth metacarpal neck fractures in adults. SEARCH STRATEGY: We searched the Cochrane Bone, Joint and Muscle Trauma Group Specialized Register (July 2004), the Cochrane Central Register of Controlled Trials (The Cochrane Library Issue 3, 2004), OVID OldMEDLINE (1951 to 1965), OVID MEDLINE (1966 to July 2004), OVID MEDLINE In-Process (July 2004), EMBASE (1988 to 2004, week 29), the Internet, and reference lists of articles. No language restrictions were applied. SELECTION CRITERIA: All randomized and quasi-randomized controlled trials which compare functional treatment with immobilization or different types of immobilization for closed fifth metacarpal neck fractures. DATA COLLECTION AND ANALYSIS: Two review authors assessed abstracts of all studies identified by the initial search, identified studies meeting the selection criteria, independently assessed the quality of the trial reports, and extracted and analysed the data. MAIN RESULTS: Five studies met the inclusion criteria including a total of 252 participants. Most studies were of poor quality. The primary outcome measure, function of the hand, was not used in any studies. There was no evidence that any of the treatment modalities was statistically significantly superior. AUTHORS' CONCLUSIONS: No included studies reported our primary outcome measure of interest, validated hand function. There was heterogeneity between the studies, which were of limited quality and size. No single non-operative treatment regimen for fracture of the neck of the fifth metacarpal can be recommended as superior to another in result. Further research is definitely warranted.

Bandages↗

[Large variation in indications for internal fixation or arthroplasty in displaced femoral neck fracture; results of a questionnaire distributed among general surgeons in 20 hospitals].

OBJECTIVE: To describe the treatment protocols for displaced femoral neck fractures in all 8 university hospitals (UH) and 12 general hospitals (GH). DESIGN: Descriptive; questionnaire. METHOD: Questionnaires were distributed to general surgeons who also perform traumatology surgery. They were requested to give succinct answers to questions about local protocol for the maximum permissible time interval between hip trauma and operation, indications for internal fixation and arthroplasty, operative technique and postoperative degree of weight-bearing in patients over 60 years of age with a displaced femoral neck fracture. RESULTS: Internal fixation and arthroplasty were performed within 24 and 48 hours respectively in 95% of all hospitals. A biological upper age limit of between 65 and 80 years old was the most commonly quoted indication for internal fixation in 70% of all hospitals. In 83% of GH dementia was considered an indication for arthroplasty as opposed to 0% in UH. Poor bone quality, immobility, comminution and inadequate reduction were incidentally quoted indications for arthroplasty. Rheumatoid arthritis, arthrosis and pathological fracture were contra-indications for internal fixation in all hospitals. Operative techniques for internal fixation and arthroplasty were similar in both UH and GH. After internal fixation, full weight-bearing was recommended in all UH and partial weight-bearing in 7 (58%) of GH. Following arthroplasty all protocols prescribed full weight-bearing. CONCLUSION: The variation in indications for internal fixation or arthroplasty reflects the lack of studies that demonstrate clearly which patient can be treated optimally with which treatment modality. There were few differences in the operative techniques of internal fixation and arthroplasty between the hospitals.

Age Factors↗

M-study; arguments for regional trauma databases.

BACKGROUND: The TRISS methodology, in combination with coefficients derived from the Major Trauma Outcome Study (MTOS), is the most widely used outcome prediction model for the care of trauma patients. Utilizing the M-statistic, different populations of trauma patients can be compared with the population originally enrolled in the MTOS. PURPOSE: We hypothesized that databases outside of North-America would not be well matched to the MTOS study and thus the TRISS methodology would not accurately predict outcome in these different populations. METHODS: All trauma studies utilizing TRISS methodology that were published between 1990-2003 were reviewed and M-statistics calculated based on the population described in the study. The populations were grouped by the following geographic locations: Europe, Asia/Africa and North-America. RESULTS: The median M-statistic for Europe was 0.65, compared with 0.88 for Asian/African databases, and 0.90 for North-American studies. There was a significant difference between European and North-American studies (p < 0.05). CONCLUSION: The trauma populations described in European studies differ significantly from the MTOS with respect to injury severity match, indicating the need for the development of regional trauma databases and modified TRISS coefficients based on the geographic location of the injured population included.

Calibration↗

Entrapment of the external iliac vein in a both-column acetabular fracture.

We present a patient with an associated both-column acetabular fracture with entrapment of the external iliac vein in the fracture. This complication was not recognized until fracture manipulation during open reduction and fixation. This case report demonstrates that an acetabular fracture can have an associated vascular injury without any obvious clinical signs. This can be especially dangerous during percutaneous manipulation and fixation of these fractures as an obstruction or injury to the external iliac vein may occur and remain unrecognized. We feel that any surgeon involved in treating patients with acetabular or pelvic fractures should be aware of this potentially serious complication.

Accidental Falls↗

[A thyroglossal duct cyst with ectopic thyroid carcinoma].

An asymptomatic swelling in the neck of a 15-year-old boy, was revealed after resection to be due to a papillary thyroid carcinoma. He was treated with a near-total thyroidectomy, radiotherapy at an ablation dosage due to a scintigraphically demonstrated remnant thyroid tissue, and thyroid hormone supplement. Almost 2 years after the tumour resection, a recurrent carcinoma was found in the neck. Prior to the resection of symptomatic thyroglossal duct cysts, it should be ascertained whether nodular thyroid abnormalities are present. In about 1% of resected thyroglossal duct cysts a carcinoma is found, most often of the papillary type. In 10-40% of the patients who undergo a subsequent thyroidectomy, malignant focuses are also found in the thyroid. In view of this multifocal occurrence and the fact that in most cases the diagnosis of carcinoma is only made after the operation, which often implies uncertainty about oncological radicalness, the authors advice to perform a (near-)total thyroidectomy as the standard procedure in case of thyroglossal duct carcinoma. After this adequate treatment with 131I should be given. A more limited approach seems only warranted when radicalness is certain and indications for nodular thyroid disease are absent.

Adolescent↗

Kinematics of the wrist with a new dynamic external fixation device.

The kinematic properties of a new dynamic external fixator device for treatment of distal radial fractures are described. Using a combination of data obtained from computed tomography scans and high-speed video images, a three-dimensional reconstruction of carpal motion was made. To describe carpal motion, the radiolunate, capitolunate, and scapholunate angles were measured during flexion and extension and during radioulnar deviation. During these types of motion, the device changed normal carpal kinematics to a limited extent although the differences in kinematic pattern with and without the device were small. The results for flexion and extension correspond with data from previously published studies with other dynamic external fixators. However, because the new device (Flexafix) allows flexion and extension and radioulnar deviation, in contrast to other dynamic external fixation devices, with its use normal carpal kinematics can be approached more closely.

Adult↗

Three-dimensional dynamic external fixation of distal radial fractures. A prospective study.

This prospective study describes the experience with a new dynamic external fixator which provides three degrees of freedom, while the centre of rotation of all these movements is located in the wrist. 44 patients with unstable fractures of the distal radius were included. During the period of dynamisation, with a median flexion of 30 degrees, extension of 18 degrees, radial deviation of 0 degree and ulnar deviation of 20 degrees the range of motion needed to perform activities of daily living was approached. In spite of early mobilisation reduction was maintained. The radiological result was excellent or good in 82% of the patients and the functional result was excellent or good in 92% of the cases. Pin track infections were noted rather frequently, possibly related to the interaction between the soft tissues and the fixator pins. Based on the experiences of the study the device needs further improvement.

Adult↗

Biomechanical analysis of dynamic external fixation devices for the treatment of distal radial fractures.

BACKGROUND: Several dynamic external fixation devices have been introduced to permit early functional treatment of unstable distal radial fractures. METHODS: An intact cadaver wrist was spanned by a dynamic external fixator. Forces between the fixator and the radius were recorded during passive motion using a single, strain-gauged pin. A device with a double ball joint was compared with a new, experimental fixator with 3 degrees of freedom and its center of rotation coincident with that of the wrist. RESULTS: During flexion and extension, the pin load was approximately the same for both fixators. Radioulnar deviation resulted in high pin loads for the fixator with ball joints; the new device showed no considerable pin load. CONCLUSION: The new device has a high degree of kinematic compatibility with the natural wrist joint. When used for the treatment of distal radial fractures, it should provide favorable conditions for the maintenance of fracture reduction compared with a device with an offset ball joint.

Biomechanical Phenomena↗

Three-dimensional dynamic AO external fixation of distal radial fractures--a preliminary report.

External fixation of unstable and intra-articular distal radial fractures has become increasingly popular. Dynamic external fixation, allowing movement of the wrist during the fixation period, is a relatively new approach which may further improve functional end results. To permit early functional treatment, the small AO external fixator was supplemented by a joint allowing all three degrees of rotational freedom. The centre of rotation is located at a point outside the device and lies approximately in the head of the capitate. With the natural centre of wrist rotation coincident with that of the fixator, admissable movements of the wrist include both flexion-extension and radio-ulnar deviation, without threatening fracture reduction. In vitro testing and initial clinical experience with a prototype are encouraging. Several improvements of the original design have been made and a multicentric clinical study is scheduled for further evaluation of the new dynamic external fixator.

Adult↗