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Biomedical subjects

J C James

Publications and source records attributed to J C James.

9 recordsLinked to original sources
PubMed1990

A sample computer system for physiological data acquisition and analysis.

This report outlines a sample configuration of a system which records, stores and analyses, graphically and statistically, neurophysiological and cardiovascular recordings during an experiment. The system is composed of sensitive physiological amplifiers, an analog to digital signal conversion board, scientific software, a 80286-based computer with 640 Kb of RAM, and a laser printer. Each component of the system is described along with the specific task(s) it performs.

Analog-Digital Conversion↗
PubMed1989

Wrongful life and wrongful birth. Implications for diagnostic sonography.

We trust that this communication will further the understanding of the concepts involved in wrongful life and wrongful birth and will assist the conduct of medical practice in such a way to minimize risks to patients and ultrasound physicians with regard to their liability. When these physicians are involved in wrongful life cases, we believe that the concepts presented will assist them in understanding the legal and societal environment in which they find themselves. We hope also that this communication may assist the defense attorney to more effectively prepare a response to the plaintiff's legal theory. Knowledge should provide understanding, if not relief.

Expert Testimony↗
PubMed1988

LL-F28249 antibiotic complex: a new family of antiparasitic macrocyclic lactones. Isolation, characterization and structures of LL-F28249 alpha, beta, gamma, lambda.

A new family of antiparasitic macrolides has been isolated from Streptomyces cyaneogriseus sp. noncyanogenus. The compounds, designated LL-F28249 alpha, beta, gamma and lambda, possess potent antiparasitic activity. The isolation, purification and structure determination by spectroscopic methods are presented.

Anti-Bacterial Agents↗
PubMed1986

Chemistry of maduramicin. II. Decarboxylation, abnormal ketalization and dehydration.

The behavior of the free acid and ammonium salt of maduramicin towards heat and alcohols is examined. In refluxing lower alcohols the free acid material is decarboxylated. In addition a bisketal decarboxylated compound as well as an A-ring monoketal decarboxylated derivative are formed. Heating the ammonium salt of the ionophores in suspension in water, or dissolved in inert solvents such as heptane or xylene can cause decarboxylation as well as concomitant dehydration of the F-ring. Reaction of dansyl chloride with the free acid of maduramicin can cause dehydration of the B-ring under very mild conditions.

Chemical Phenomena↗
PubMed1986

Chemistry of maduramicin. I. Salt formation and normal ketalization.

The formation of monovalent and divalent salt complexes of maduramicin is described and the 13C NMR chemical shift assignments of these materials are tabulated and discussed. In the spectrum of the thallium salt, 20 of the 47 signals are split due to the thallium-carbon coupling. Similarly the preparation of both the free acid and the sodium salt complexes of the normal methyl and ethyl ketal derivatives of maduramicin are outlined. Their 13C NMR spectra are fully assigned together with discussion of displacements observed due to this derivatization.

Carbon Isotopes↗