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Biomedical subjects

J C Libersa

Publications and source records attributed to J C Libersa.

At least 19 recordsLinked to original sources

[Giant-cell reparative granuloma: a case report].

We report a case of giant-cell granuloma located in the maxilla of a 9-year-old child. The pathogenesis of giant-cell reparative granuloma (GCRG) remains obscure. Radiological features are variable. Radiolucency or well or ill-defined uni-or multilocular aspects with trabeculations can be observed. Symptoms of compression on the adjacent tooth's root and pathology findings confirm the diagnosis. Curettage is effective and recurrence is rare.

Child↗

[Dental anomalies following anticancer chemotherapy].

Chemotherapy administered during childhood may induce dental abnormalities, such as acquired amelogenesis imperfecta, microdontia, hypodontia and altered root morphology. The magnitude of the defect varies according to the cytotoxic agents, the duration of their use and the stage of tooth development at the time of chemotherapy. Patients who received high-dose chemotherapy before the age of 5 are particularly concerned. The dental supervision of these children is based upon three orthopantomograms: the first one has to be performed before starting chemotherapy and will be used as a reference; the second is done soon after the drug therapy in order to evaluate the first consequences; the third is performed after the eruption of all permanent teeth (age 12-13 in average) in order to determine the dental abnormalities. In case of hypodontia, orthodontic treatment must be considered, but it is necessary to take into account the fact that it may increase the risk of root resorption. Preventive dental care is important for these children. It involves meticulous oral hygiene and frequent dental visits to assess and maintain dental health.

Antineoplastic Agents↗

[Chemotherapy and dental growth].

A prospective study about the development of the mandibular second right molar, has been performed with 17 chemotherapy treated children in the Paediatric Oncology department of the Centre Oscar-Lambret (Lille). Our method is based upon the measure of the crown or root length for different periods: periods with or without chemotherapy. These measurements have been performed every 6 months for 18 months with orthopantomograms. We notice for both the crown and the root: a significant difference in growing speed between periods with an without chemotherapy; a speeding up of the mineralization at the end of the treatment rejoining the average figures of a healthy test population.

Adolescent↗

[Alveolitis].

Explore the source record for details and available documents.

Alveolar Process↗

[Mesoscopic anatomy of the peribuccal facial muscles].

In 16 human face dissections under the operative microscope, the authors recall the classical anatomy of perioral muscles. Instead of the 3 muscles around the nostrils, they prefer to discern two layers: deep and superficial. The subnasal region can similarly be dissociated. Resuming the commissural node study they insist upon the peculiar role of the platysma muscle and its expansions, and upon the tight imbrication of buccinator and orbicularis oris muscles.

Cheek↗

[Cleaning implantation burs. Observations using scanning electron microscopy].

Drastic aseptic conditions are necessary in implantological treatments. A good sterilizing procedure of the specific instrumentation, like drills, is based on an efficient cleaning. Because of their design, the cleaning of drills is a real challenge. The aim of this investigation is to evaluate two different cleaning procedures usually used by implantologists. One is based on a manual cleaning, the other on an ultra-sonic cleaning. The instrument observed by scan-electron-microscope, is a I.T.I. system drill. The results show the superiority of the ultra-sonic cleaning. The manual cleaning is especially ineffective on the inside and the cutting part of the drill. Even if ultra-sonic cleaning is definitely a better procedure, it has to be improved. A extensive study should be conducted to optimize the cleaning parameters, if not, single-use drill should be definitely preferred by implantologists.

Dental Implantation, Endosseous↗

[Raman spectrometry applied to calcified tissue and calcium-phosphorus biomaterials].

The rigid part of the human body consists essentially of carbonated apatite (calcium phosphate). Biologists don't have any tools to study this "mineral" phase, though its origin is organic. A new approach of some compounds like enamel or bone is obtained with the Raman micro-characterisation by a very fine analysis of chemical bonds in a micrometric scale. This method allows the characterisation, the analysis and the dosage of ions, like carbonate, acid phosphates, proteins and fatty acids. The identification of other organic or mineral compounds (e.g. calcium carbonate, calcium oxide, substitutant ions...) is also possible. The Raman microspectrometry can also be used to study the chemical and physical properties of biomaterials and their evolution after implantation in a dental or bone site. On synthetical calcium phosphate, beta-TCP, brushite and hydroxyapatite can be distinguished and the impurities found in plasma spray deposits can be measured. The detection of alpha-, beta-, or gamma-pyrophosphates could be obtained in some commercial beta-TCP. The Raman microspectrometry is the only non-destructive method which allows the identification of the chemical bonds in a micrometric scale and gives the "fingerprint" of the studied component.

Animals↗

[A technic using MRI. A comparative study of 3 anesthetic technics of the inferior alveolar nerve].

In our study we used M.R. sectional imaging in the axial and coronal planes to investigate three alveolar nerve anaesthesia techniques: Gow Gates, Akinosi and Classical techniques. Furthermore, anatomic sections were made using cadaveric specimens in axial and coronal planes to visualize anatomical relations of the anaesthetic drug. The present study showed the more or less important and quick spreading of the anaesthetic drug through the infra temporal area depending on the anaesthesia technique. Possible incidents are also discussed.

Anesthesia, Dental↗