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Biomedical subjects

J C Lipman

Publications and source records attributed to J C Lipman.

7 recordsLinked to original sources

Ureteral neoplasms.

The authors review primary and secondary neoplastic lesions of the ureter. Primary ureteral tumors are rare, although when they occur, they usually consist of transitional cell carcinoma. The most frequent symptoms are hematuria, frequency, dysuria, and pain. Secondary ureteral neoplasms are caused by direct extension from an adjacent extraureteral primary tumor or from a site of bulky metastasis and, rarely, by metastasis from a distant primary tumor. The most useful diagnostic modalities are retrograde pyelography for direct visualization of ureteral involvement--particularly in the presence of high-grade obstruction--and computed tomography for evaluation of extraureteral extent of tumors and the presence of lymphadenopathy and distant metastases.

Carcinoma, Transitional Cell↗

The radiology of cavernous hemangioma of the liver.

This article reviews the epidemiology, pathology, and diagnosis of cavernous hemangioma of the liver. This lesion is very common; it is the most common benign tumor of the liver. While small hemangiomas (less than 3 cm) have a characteristic ultrasonographic appearance, lesions larger than 3 cm in diameter may have a whole host of ultrasonic findings and this technique becomes less reliable in making the diagnosis. Initial experience with dynamic CT has shown it to be reliable in differentiating hemangiomas from other lesions. Later, some metastatic lesions were described to mimic hemangiomas on CT. Furthermore, a diagnostic CT is hard to get in small lesions because of the difficulty in getting a small lesion in the scanning plane repeatedly. Blood pool scintigraphy with planar imaging has been shown to be very sensitive and specific for that lesion. This technique is not very reliable for small (less than 2 cm) or deeply seated lesions. We have shown that blood scintigraphy is more reliable for those situations. Recent reports have shown that MRI is highly reliable for the detection and characterization of liver hemangiomas. This technology is very expensive and is unlikely to be used in evaluating all patients suspected of having cavernous hemangiomas; it should be reserved for cases with uncharacteristic ultrasound or blood pool scan findings.

Angiography↗

Medullary carcinoma of the breast: mammographic and US appearance.

Medullary carcinoma of the breast is an uncommon tumor, which may mimic a benign mass at both mammography and ultrasonography (US). A total of 24 medullary carcinomas visible at mammography appeared as round or oval, noncalcified masses with varying degrees of marginal lobulation. In six of the 24 patients, US demonstrated well-defined masses with an inhomogeneous, hypoechoic texture. There was no attenuation of sound, and all lesions showed enhanced through transmission.

Adult↗

Unusual solitary soft tissue metastases from renal cell carcinoma.

Adenocarcinoma of the kidney may metastasize to many organs and remain undetected for years. We present three illustrative cases of patients who had solitary recurrences in unusual locations; two of the three presented more than eight years after having undergone nephrectomy. Recognition of these unusual presentations is important in proper patient management.

Adult↗

Detection of hepatic metastases in diffuse fatty infiltration by CT: the complementary role of imaging.

Six patients undergoing computed tomographic (CT) evaluation for possible abdominal and pelvic metastases were shown to have diffuse fatty infiltration of the liver and findings indeterminate for hepatic metastases. In two patients with diffuse fatty infiltration and no focal hepatic lesions on CT, technetium-99m sulfur colloid imaging demonstrated focal hepatic defects confirmed to represent metastases. In four patients with diffuse fatty infiltration and hyperdense liver foci on CT, radionuclide imaging demonstrated normal uptake in the hyperdense foci confirmed to represent areas of normal liver spared by fatty infiltration. In each of the six patients, clinical management was altered by the radionuclide findings.

Fatty Liver↗