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J C Lorenzo

Publications and source records attributed to J C Lorenzo.

12 recordsLinked to original sources
PubMed1995

Fibrin glue is a sealant and not a nerve barrier.

This experimental work on the internal popliteal nerve of the rabbit was undertaken to clarify whether interposition of a block of 4 mm of fibrin-sealant would form a barrier which stops or interferes with the passage of the axons. Twenty-four adult rabbit tibial nerves were placed in a microclamp, sectioned, and separated 4 mm. The gap between the two nerve ends was filled with fibrin sealant. Eight weeks after the procedure, the animals were sacrificed and the nerves removed. Histologic studies and morphometric longitudinal and transverse examination by image analysis showed that interposition of the block of fibrin sealant between the nerve ends was not a barrier or obstacle to the passage of axons. The use of fibrin sealant is a relatively good experimental model for a chamber of regeneration, because 70 percent of axonal regeneration was obtained.

Animals↗
PubMed1992

Sterile transient neonatal pustulosis is a precocious form of erythema toxicum neonatorum.

A sterile pustular skin eruption was observed in 17 of 3,541 newborn infants examined over a period of 30 months. The skin eruption was always present at birth and fulfilled the clinical criteria of transient neonatal pustular melanosis (TNPM). However, some days after birth, all of them but 1 developed skin lesions typical of erythema toxicum neonatorum (ETN). Histological examination of 11 biopsies obtained at the age of 1 day showed intracorneal neutrophilic pustules in 4 and subcorneal intraepidermic eosinophilic pustules in 7. On the basis of our findings and a literature review we consider that a clear-cut differentiation between TNPM and ETN is not always possible. We propose the name sterile transient neonatal pustulosis to unify these conditions.

Diagnosis, Differential↗
PubMed1981

The morbid anatomy of the skeleton in osteogenesis imperfecta.

Clinically, the two most prominent features of osteogenesis imperfecta are dwarfing and bone fragility. Radiologic examination reveals severe osteopenia with or without multiple deformities. Histological examination of samples obtained from 16 iliac crest biopsies compared with 21 age-matched controls revealed a significantly diminished amount of bone matrix without an associated decrease in the number of bone cells, suggesting a quantitative deficiency of collagen production. Radiologic studies of 46 affected children and autopsy studies of two children revealed abnormalities in the ossification of the secondary centers of ossification, together with evidence of fracture and fragmentation of the epiphyseal growth plates causing a characteristic radiologic appearance which may be likened to a bag of popcorn. These epiphyseal abnormalities may contribute to the limb shortening in some cases.

Bone and Bones↗
PubMed1980

Giant-cell reparative granuloma of short tubular bones of the hands and feet.

Eight cases of giant-cell reparative granuloma were encountered in the short tubular bones of the hands and feet. This entity was originally described by Jaffe as a jaw lesion. Subsequently the lesion was found in the skull and facial bones. The name "giant cell reaction" was applied to similar lesions found in the short tubular bones of hands and feet. Thirteen prior cases have been reported and none recurred. Of the eight new cases described herein, four have recurred one or more times, requiring further treatment. No association with hyperparathyroidism was found. We prefer to designate these lesions as giant cell reparative granulomas of extragnathic sites. Because of overlapping ultrastructural and light-microscopic features, as well as similar biologic behavior, we feel that aneurysmal bone cyst and these giant-cell reparative lesions represent related responses to intraosseous hemorrhage.

Adolescent↗
PubMedDate not supplied

The subtalar joint: embryology and morphology.

Several different aspects of the subtalar joint are studied. Embryology indicates that it is a recently acquired structure. The anterior subtalar joint does not have a uniform morphology, and it has been subdivided into three anatomical descriptions (ovoid, bean, and two part). To correct the confusion found in other papers, we intend to clearly describe the anatomy of the ligaments. The form and function of the retinacula, cervical ligament, and ligament of the canal are studied. The microscopic anatomy of ligaments is studied, dealing specifically with their innervation and the structure of their fibers.

Ankle Joint↗
PubMedDate not supplied

[Gorham's disease].

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Adult↗