[Regression of initial tuberculosis in a hospital environment].
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Biomedical subjects
Publications and source records attributed to J C Marchand.
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The influence of D,L-ethionine (5 mM) was tested on hepatocytes isolated from fed or fasted rats. The digitonine fractionation procedure [6] was used to determine the repartition of adenine nucleotides and inorganic phosphate. Ethionine induces a decrease in the intracellular ATP content; this decrease is located both in the cytosol and in the mitochondria of fed and fasted rat hepatocytes. The observed effects of ethionine are: 1) fed rats: increase in glycolysis, decrease in mitochondrial ATP/ADP x PO4 and mitochondrial NAD+/NADH ratios; 2) fasted rats: decrease in neoglucogenesis from lactate + pyruvate or alanine, decrease in cytosolic ATP/ADP x PO4 and cytosolic NAD/NADH ratios.
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