Biomedical subjects

J C Marco

Publications and source records attributed to J C Marco.

6 recordsLinked to original sources

PubMed2001

Relationships between infection with caprine arthritis encephalitis virus, intramammary bacterial infection and somatic cell counts in dairy goats.

Somatic cell counts, the bacteriological condition of the milk and antibodies against caprine arthritis encephalitis virus (CAEV) were measured monthly throughout lactation in 121 lactating goats of the Murcia-Granada breed in four commercial dairy goat herds. The prevalence of bacterial intramammary infection was 5.6 per cent and the prevalence of CAEV infection was 20.6 per cent. An analysis of variance revealed a significant effect of herd, intramammary infection and the interaction between intramammary infection and CAEV on the somatic cell count. In udder halves free of intramammary infection, the somatic cell counts were significantly lower in seronegative goats than in seropositive goats (P<0.05), but the difference was not significant in udder halves persistently infected by bacteria. There was a significant increase in somatic cell counts due to bacterial intramammary infection (P<0.01) in the seronegative goats, but this effect was not present in the seropositive animals.

Animals↗

PubMed1999

Bovine abortion associated with Neospora caninum in northern Spain.

During 1996, aborted bovine fetuses from dairy herds in norther Spain were examined by histopathological, immunohistochemical and serological methods for evidence of infection by Neospora caninum. Microscopical brain changes consistent with those of neosporosis were detected in 36 of 81 fetuses and specific antibodies (IFAT titres > or = 1/16) in 32 of 63. Eight fetuses with neurological lesions were seronegative, and eight without lesions were seropositive. In 25 of 34 fetal brains with lesions consistent with published descriptions of neosporosis, immunohistochemical analysis revealed the presence of N caninum antigen. Depending on the diagnostic criteria, the prevalence of neosporosis related to bovine abortion was between 32 and 57 per cent of the fetuses submitted and between 33 and 58 per cent of the herds involved. Data on the geographical, seasonal and fetal age distribution of the infection are given for the fetuses examined and the value of the different diagnostic methods is discussed.

Abortion, Veterinary↗

PubMed1995

[Psychologic morbidity in thyroidectomized patients].

To study psychological disorders and personality in a series of patients scheduled to undergo thyroidectomy under general anesthesia. We selected 33 patients who were to undergo thyroidectomy during the second half of 1993. Socio-demographic data were collected and the patients were given the following battery of psychometric tests: Cognitive Mini-Test (CMT), which explores the main cognitive areas; Goldberg's General Health Questionnaire (GHQ-28), which is a tool for screening out probable cases of mental illness (mainly involving affective disorders); and Cattell's Personality Questionnaire 16-PF. With the GHQ-28 we detected a 29.6% prevalence of mental illness before surgery; this figure increased to 33.31% after surgery with a cut-off point of 5/6. Some 3.7% of this series of patients presented general cognitive disorders when evaluated with the CMT. One in 3 patients shows signs of significant mental illness and could benefit from some type of psychological or psychopharmacological support, or even psychiatric treatment in the worst cases. We propose that the anesthetist learn to use these simple instruments for psychopathological evaluation in order to detect problems.

Adult↗

PubMed1991

Comparison of different media for the isolation of small ruminant strains of Mycobacterium paratuberculosis.

Two different egg based media, with and without the incorporation of sodium pyruvate, were used to isolate M. paratuberculosis from sheep, goat and cattle samples obtained at our laboratory for two years. Both media were adequate for bovine material, with a slightly improved isolation rate for Herrold's egg yolk medium incorporating sodium pyruvate; however, most of the small ruminant strains grew only on Löwenstein-Jensen medium without sodium pyruvate. Those results point out the need to use different media when working with small ruminant samples and provide further evidence for the existence of different varieties of M. paratuberculosis causing paratuberculosis in cattle and in small ruminants.

Animals↗

PubMed1987

Caprine arthritis-encephalitis in the Basque country, Spain.

A goat herd severely affected by arthritis was studied. The most representative clinical signs consisted of articular swelling, mainly of the carpal joints, and the subsequent locomotor disorders. Some goats also showed signs of central nervous system involvement. Examinations of joint fluid revealed an increased number of mononuclear blood cells, mostly lymphocytes. Gross and microscopic articular lesions were of inflammatory and degenerative types. Periarticular connective tissue, synovial bursae, tendons and tendon sheaths were predominantly affected. Inflammatory lesions were those of a chronic hyperplastic tenosynovitis with fibrosis of the connective tissue components. Degenerative changes consisted mainly of necrosis and mineralisation of articular-related structures. Histological lesions in the central nervous system were those of a nonpurulent encephalitis initially located in periventricular areas, but in one case extensive encephalomalacia was also seen. Of the 80 animals sampled 82.5 per cent showed seropositive reactions against an ovine progressive pneumonia virus antigen. None was seropositive to brucella and titres to chlamydia were low. Attempts to isolate chlamydia and mycoplasma from affected joints and several organs failed. Different bacteria were recovered from a few samples but did not seem significant. Syncytium-forming viral particles were isolated from several organs, mainly the lungs, synovial membranes and lymphoid tissue of almost all the slaughtered animals. These particles were identified as lentiviruses by electron microscopy. The clinical signs, lesions serological results and microbiological findings, led to a diagnosis of caprine arthritis-encephalitis. This syndrome has not been recognised in Spain previously.

Animals↗

PubMedDate not supplied

[HLA antigens in bipolar affective patients].

The presence of H.L.A. antigens in bipolar affective patients attending in the University Hospital of Zaragoza was studied and contrasted with findings in the general population. A random sample of 36 patients was selected for the study. All of them fulfill, both, DSM-III and RDC diagnostic criteria . The HLA antigen was studied by means of Lymphotoxicity Test of N.I.H. standard technique. Both, A29 and B21 HLA antigens were detect in the bipolar patients more frequently that in the controls (Histocompatibility Testing data, 1980), and the differences were statistically significant. It is also suggested that the A2 HLA antigen is more frequently found in bipolar patients "non-respondent" to lithium treatment. The inclination to relate these antigens to specifics genes in the bipolar illness should be pondered, since the risk of "false positives" inherent in studies testing association hypothesis is well known.

Bipolar Disorder↗