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Biomedical subjects

J C O'Sullivan

Publications and source records attributed to J C O'Sullivan.

8 recordsLinked to original sources

AANA Journal course: update for nurse anesthetists--utilizing the Ohmeda draw-over vaporizer in the operating room.

The draw-over anesthesia system (DOAS) is a portable, lightweight, safe system for administering anesthesia in a remote or disaster situation. Unfortunately, the DOAS (which has many models worldwide) cannot be used in a modern operating room because it lacks safety monitors that are required by the Joint Commission on Accreditation of Healthcare Organizations and Harvard standards. Therefore, this article examines modifications to the DOAS to permit staff familiarization with it in a modern operating room. All anesthesia providers who have an interest or obligation in assisting in civil defense, humanitarian missions, or volunteer healthcare organizations should be aware of this anesthesia delivery system, its unique characteristics, and this suggested method of familiarization.

Adult↗

Surgery following chemotherapy and radiotherapy for advanced carcinoma of the cervix.

Ten patients with advanced squamous carcinoma of the cervix have been treated with both radiotherapy and monthly cyclical chemotherapy. All patients have subsequently undergone a simple hysterectomy and bilateral salpingo-oophorectomy with para-aortic and pelvic node biopsy. Six patients were found to be histologically free of disease, 2 patients had residual cervical disease completely excised, and 2 patients had persistent intra-abdominal disease. Eight patients have survived 24-43 months one of whom has recurrent disease. The addition of chemotherapy to standard radiotherapy appears to have improved the results of treatment, however, in view of the high complication rate (50%) it is considered that surgical assessment of response is not justified and that surgery should only be undertaken where there is good evidence of persistent but operable disease.

Adult↗

Airway closure and pregnancy.

During pregnancy there is a fall in functional residual capacity and expiratory reserve volume. The point of airway closure in relation to vital capacity and the expiratory reserve volume was determined in 11 post-partum patients who had previously been studied during pregnancy. The lung volume at which airway closure occurred in pregnancy and the post-partum period did not change in relation to the vital capacity whereas the expiratory reserve volume did, so that airway closure became imminent in the pregnant women during tidal ventilation, especially whilst in the suping position. The significance of this alteration in pulmonary function to obstetric anaesthesia is discussed.

Adult↗

Closing volume and pregnancy.

Measurements of closing volume have been made in 20 women between the 36th and 40th weeks of pregnancy. The patients were studied in the erect and supine positions and the point of airway closure was related to functional residual capacity. The results show that airway closure occurred during tidal ventilation in 10 patients in the erect position and in six patients in the supine position. These results may explain the variation found in maternal arterial oxygen tension during pregnancy.

Arteries↗