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J C Pedrazzani

Publications and source records attributed to J C Pedrazzani.

6 recordsLinked to original sources
PubMed1996

Protective efficacy of BCG against leprosy in São Paulo.

The case-control study reported here evaluated the protective effect of BCG vaccine against leprosy in São Paulo, Brazil. Seventy-eight patients under age 16 who had been diagnosed as having leprosy (cases) and 385 healthy individuals (controls) were selected and matched by sex, age, place of residence, and type of exposure to leprosy (intradomiciliary or extradomiciliary). The cases were drawn from an active patient registry and from a group of new leprosy cases treated at 50 health centers in the cities of Bauru and Ribeirão Preto in the state of São Paulo. In order to estimate the protective effect of BCG, the prevalences of BCG scars in cases and controls were compared. The presence of one or more scars was associated with an estimated protective efficacy of 90% (95% confidence interval: 78% to 96%). Stratified analysis by age group, sex, socioeconomic level, and clinical form of the disease revealed no significant differences in the protection provided by the vaccine. However, it seems clear that more data will be needed in order to accurately assess the true relevance of BCG for leprosy control programs.

Adolescent↗
PubMed1995

[Study on the incidence of adolescent births in a municipality of the state of Sao Paolo].

The main goal of this study is to find out the rate of childbirth by teenager mothers in São Carlos-SP from july, 1993 to july, 1994. The data were collected during one year and showed that in 14.72% of the birth the mothers were 11 to 18 years old. The data were also analysed in terms of, number of pregnancies, occupation, type of birth, and the mother's marital status. The results are discussed in terms of their implication with regard to educational programs to adolescents.

Adolescent↗
PubMed1995

[The protective efficacy of BCG against leprosy in São Paulo, Brazil].

The protection against leprosy conferred by BCG vaccination was evaluated in a case-control study. Selected for the study were 97 patients under 16 years of age who had been diagnosed with leprosy (cases) and 385 healthy persons (controls), who were matched according to sex, age, place of residence, and type of contact (intra- or extradomicilliary). The cases were selected from a register of active cases as well as a series of new leprosy patients treated in 50 centers in the city of São Paulo, Brasil. To estimate the protective effect of BCG, the prevalences of BCG scars among cases and controls were compared. The presence of one or more scars was associated with a protective efficacy of 90% (95% confidence interval: 78%-96%). Stratified analysis by age group, sex, socioeconomic level, and clinical form of leprosy did not reveal any important differences in the protection conferred by the vaccine. The significance of these findings and the appropriateness of using BCG in leprosy control programs is discussed.

Adolescent↗