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J C Petersen

Publications and source records attributed to J C Petersen.

8 recordsLinked to original sources

Mammography in women under age 30: is there clinical benefit?

With the increasing utilization of mammography, young women under age 30 are being referred for mammographic examination more frequently. A review of the mammograms of 76 patients, aged 18-29 years, was conducted to evaluate the clinical utility of the examination in this age group, for whom the probability of malignancy is quite low and the risk of radiation carcinogenesis may not be negligible. In 74% of patients referred for study of a palpable mass, no mass was evident on mammograms. When a mass was seen, the radiographic features did not influence clinical management. Radiologists should inform their clinical colleagues regarding the risks and limitations of mammography in women under age 30 and encourage more frequent utilization of ancillary diagnostic procedures including sonography and diagnostic aspiration.

Adolescent

Rapid immunoelectrophoretic assay for detection of serum antibodies to Aspergillus fumigatus catalase in patients with pulmonary aspergillosis.

A rapid immunoelectrophoretic assay was developed to detect antibodies to Aspergillus fumigatus catalase. The method's diagnostic sensitivity for pulmonary aspergillosis was 88% (72-97%, 95% confidence limits) in 33 patients presenting with either aspergilloma or Aspergillus lung infiltrate. The diagnostic specificity was 94% (90-97%) as judged from 191 patients with other infiltrative lung diseases, including infections and neoplasia. None of the 185 healthy subjects had catalase antibodies. The highest titres (ranging up to 256) were found in aspergillosis patients with cavitary lesions. Catalase antibody titres increased in two patients with concomitant development of lung cavities and mycetomas. In patients with resected or stable Aspergillus lung disorders catalase antibody titres declined by less than one dilution step per year.

Adolescent

Taking laetrile: conversion to medial deviance.

For members of the CCS, laetrile use occurs in a self-help social context where users derive substantial social and emotional support from fellow members. We are convinced that much of the appeal of laetrile results from this social context in which it is frequently used. The CCS and the extensive network of similar organizations are fulfilling unmet needs in cancer patients and those fearful of cancer. Until conventional cancer therapy deals more successfully with the social and psychological needs of cancer patients, promoters of laetrile will till fertile ground.

Amygdalin