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J C Petithory

Publications and source records attributed to J C Petithory.

At least 19 recordsLinked to original sources
PubMed1995

Anisakidosis: report of 25 cases and review of the literature.

Anisakidosis (previously known as anisakiasis) is a disease caused by the accidental ingestion of larval nematodes (Anisakis and sometimes Pseudoterranova) in raw fish. Two groups of patients are studied: 5 clinical cases and 20 serological diagnoses. 55 French cases are already published. Most of them complained of acute symptoms, which occurred within 12 h of eating the seafood meal--epigastric pain, occlusion, diffuse abdominal pain, and appendicitis. Larvae were attached to the gastric mucosa (25 cases), including an inflammatory response (erythema, oedema ulceration). Diagnosis of anisakiasis is made by gastroscopy which allows removal of the worms, and cures the patients. In gastro-intestinal tract X-rays, oedema in the mucosa, pseudo tumour formation, and filling defects (worm) were observed. In chronic infections, cases with intermittent feelings of ill health and abdominal pain, lasting from several weeks to months, were misdiagnosed as another intestinal disease. Positive serological reactions are helpful, and surgery is necessary for resection of the lesion; diagnosis is made histologically by an eosinophilic granuloma, and the presence of a larva with Y shaped lateral cords. Infestation rate is high in fishes: cod (88%), rock fish (86%), herring (88%), salmon, mackerel. Public health education should discourage the eating of raw fish. Thorough cooking to 70 degrees C or adequate freezing to -20 degrees C for 72 h are the best preventive measures. Such legislation is only in force in the Netherlands, where cases have decreased dramatically.

Abdominal Pain↗
PubMed1995

[Study of 6 cases of malaria acquired near Roissy-Charles-de-Gaulle in 1994. Necessary prevention measures in airports].

During the very hot 1994 summer, six new cases of airport malaria have been observed in and around Roissy-Charles-de-Gaulle airport. Four patients were regular or occasional airport employees. The two other cases were inhabitants of a city at 7 km. Entomological investigations suggest that cars of airport employees served to disseminate anophelines outside the airport areas. The six cases were very severe. One patient died. Apparently, W.H.O. recommendations on aircraft disinsecting procedures have not been fully followed. There is obviously a threat for areas near the airports.

Adult↗
PubMed1994

[Entamoeba histolytica (Schaudinn 1903) and Entamoeba dispar (E. Brumpt 1925) are 2 different species].

On the basis of epidemiologic and clinical data in humans, and of experimental studies in kittens, E. Brumpt in 1925 showed that Entamoeba histolytica producing quadrinucleate cysts was a complex of 2 species. He differentiated a pathogenic and invasive form, from a non pathogenic and non invasive one that he called Entamoeba dispar. His explanation gained little support until recently, when Sargeaunt reported a study of isoenzyme typing and allow then the classification of amoebae resembling E. histolytica in pathogenic and non pathogenic species. Monoclonal antibodies and PCR have recently been used and have shown to react specifically with the two forms of amoebae. Genetic evidence has also demonstrated that the pathogenic and non pathogenic amoebae represent different species.

Animals↗
PubMed1994

[Ascaridiasis zoonoses: visceral larva migrans syndromes].

The syndrome of Visceral Larva Migrans is a zoonotic disease due to the migration in human of nematodes larval, specially ascarid. Since the larvae fail to complete their migrating cycle in humans, the diagnosis of Toxocariasis infection remains only serologic. We have been able to demonstrate by the technique of agar diffusion and the Western-blotting method that the etiology due to Toxocara canis was twice as much frequent as the one due to Toxocara cati in the syndrome of Visceral and Ocular Larva Migrans. The use of numerous antigens from adult nematodes, mainly Ascaris suum, has shown, than in France, in the syndrome of VLM at least 12% of the cases were certainly due to other nematodes. Nippostrongylus brasiliensis (or another similar nematode) of the rat might be responsible. The existence of numerous clinical and biological cases found negative in serology, allow us to suggest that some other larval nematodes, may be from wild animals, might play an etiological role.

Animals↗
PubMed1992

Biological modifications of the vitreous in intraocular parasitosis: preliminary study.

In intraocular parasitosis the immunologic reactions in the vitrectomy-fluids depend on the parasitic agent: there is a lymphocytical reaction without any IgE production in toxoplasmic chorioretinitis, whereas there is a strong hypersensitivity reaction with a local IgE production as well as the presence of eosinophils and an antigenic stimulation in fluids with toxocara parasitosis. The electrophoretic patterns are quite similar in both cases.

Adolescent↗
PubMed1992

[Biological study of a case of colonic anisakiasis. Review of the literature].

An eosinophilic granuloma was found in the operative specimen from a patient who underwent colonic resection eleven days after onset of abdominal pain. Upon questioning, the patient reported having eaten raw fish eggs (cod) on the day before the onset of abdominal pain. Colonic localization of this anisakiasis, although more common in Europe than in Japan, is nevertheless infrequent, with only 17 other cases having been published to date. Eosinophil counts rose after 15 days and specific serologic tests became positive after 21 days with titers remaining detectable longer by Western blot (31 months) than by immunoelectrophoresis (2 months). Routine serologic tests for anisakiasis in patients with eosinophilic granulomas of the digestive tract would ensure the correct etiological diagnosis in some cases.

Adult↗
PubMed1991

[Seroepidemiologic data on anisakiasis. Prophylactic consequences for fish products].

The Western blotting method allowed us to confirm the diagnosis in 7 cases of acute anisakiasis, to assess it in 5 cases of chronic anisakiasis, and to follow up the evolution. These chronic frames according to the question of their long term evolution, and the part played by Anisakis simplex in fish nutritional allergy increase the negative score of that parasite. This situation should lead to discuss preventive rules.

Acute Disease↗
PubMed1991

[Seroepidemiological data on anisakiasis: prophylactic consequences in fish products].

The Western blotting method allowed us to confirm the diagnosis in 7 cases of acute anisakiasis, to assess it in 5 cases of chronic anisakiasis, and to follow up the evolution. These chronic frames according to the question of their long term evolution, and the part played by Anisakis simplex in fish nutritional allergy increase the negative score of that parasite. This situation should leave to discuss preventive rules.

Acute Disease↗
PubMed1990

[Current status and trends in quality control in parasitology and mycology].

The survey of the results of the control quality in Parasitology and Mycology showed in general an improvement in the correct diagnosis for the specimen analysed (preparations of parasites, smears, stools, sera, fungal cultures). The wrong diagnosis of Ascaris lumbricoides eggs in stools diminished from 5% to 1.5%. The trichrome Gomori-Wheatley stain technic on smears in PVA was introduced. 16 reference or national standards sera for the parasitological serology, including 6 for toxoplasmosis and one for candidiasis were established. The increasing number of participants (more than 4,000) and particularly for the serology of toxoplasmosis showed the interest of the biologists for the quality of their tests.

Animals↗
PubMed1989

[Ancylostomiasis in the mines. Apropos of 2 cases].

The etiological importance of Ancylostomidae in miners' anaemia has been discovered in 1880 by Perroncito during the boring of the Saint-Gothard tunnel in a dreadful epidemic. Thereafter in France, the illness disappeared between 1930 and 1940 because of the preventive dispositions realized. Two present cases of contamination in the coal mines of Lorraine due to N. americanus drive us to remember the interest of systematic faecal examinations of the miners at the engagement and every five years.

Adult↗
PubMed1989

[Opportunistic aspects of parasitosis].

Parasitosis opportunist are becoming clearer thanks to a better knowledge of immunological mechanisms, especially in AIDS. Child immunological immaturity and corticotherapy are the two other main immunodeficiencies among opportunist parasitosis. For the protozoosis, coccidiosis (especially toxoplasmosis), cryptosporidiosis, but isosporosis too and microsporidiosis represent a privileged group among opportunistic infections. Among adult, leishmaniasis caused by L. infantum is an opportunist parasistosis, favoured by corticotherapy or AIDS, but among children, it is the child's immunological immaturity which is involved in the immunodeficiency. Babesia occurs among splenectomized people. Giardiasis is more frequent and more severe among IgA immunodeficiencies especially secretories IgA. Among helminthiasis, generalised strongyloidiasis is very severe among patients under corticotherapy, but AIDS is not involved.

Acquired Immunodeficiency Syndrome↗
PubMed1989

[The inner body of Loa loa microfilariae. Morphologic and physiopathologic data].

The innenkörper is visible in 80% of the cases of microfilariae Loa loa we have studied and stained at pH 7.2. In thick blood film, however, it was not visible. It lies between the middle of the body and the G1 = R1, cell. The central viscus rarely take the form of a single elongated mass, it most often appears moniliform with 2 to 5 granular masses and it is sometimes reduced to a few number of granulations. Its average length is 34 microns. As with W. bancrofti it would appear to have the role of a nutritional reserve.

Animals↗
PubMed1989

[Prevention of AIDS transmission by syringes and needles in France and Africa].

A study made among drug addicts in the Northern suburbs of Paris enables establishing a stabilisation of positive H.I.V. serology prevalence among them, a fact related to the free sale of syringes and needles. In Africa, the nosocomial transmission of H.I.V. by non-sterilisable but reused needles and syringes is demonstrated, and two cases are described. Its importance is certain but must be precise. The prevention of this epidemiological modality must be done by systematic use of reusable and sterilisable injectable material.

Acquired Immunodeficiency Syndrome↗
PubMed1985

[Cellular and humoral immunity in hyperimmune malaria].

The tropical splenomegaly syndrome, described by Charmot as a chronic splenomegaly without any acute malaria attack, appears to be the prototype of hyperimmune malaria. A very small number of red cells or even no red cells are infected. IgG and/or IgM rates are greatly increased, as are anti-Plasmodium antibodies. The ratio T. helper/T. suppressor is normal or slightly increased. Serological tests show often cross reactions, mainly with African trypanosomiasis and toxoplasmosis, also with leishmaniasis. Undefined genetic factors in the host could explain the syndrome.

Adolescent↗
PubMed1983

[Hypocalcemia in malaria. Study of correlations with other parameters].

In a privileged observation of severe malaria contracted after laboratory contamination, we noticed a deep hypocalcemia 67 mg/l = 1.67 mmol/l. Since then we found again that hypocalcemia, connected with hypoalbuminemia, in ten other patients showing severe forms of malaria Plasmodium falciparum. The main biological datas of those four cases are summarized below. We made a systematic study of malaria cases, whatever may have been the intensity of parasitemia and clinical symptoms, and whatever the plasmodial species. For 26 non african paludisms , we found an average level of calcemia of 85 mg/l and an average hypoalbuminemia of 37 g/l = 536 mumol/l. For 30 african paludisms we found an average calcemia of 87.5 mg/l. That reduced value is statistically significant comparatively with the average value of 30 african people with no malaria 91.5 mg/l. The problem is to know if this hypocalcemia is connected only with hypoalbuminemia and if it may involve clinical or therapeutical effects.

Adult↗