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Biomedical subjects

J C Phero

Publications and source records attributed to J C Phero.

At least 19 recordsLinked to original sources

Assessing the need for anesthesia and sedation in the general population.

The authors used a national telephone survey to examine the relationship between dental anxiety and the use of pain and anxiety control measures in the general population. Nearly 30 percent of respondents reported being somewhat nervous, very nervous or terrified about going to the dentist. There was a threefold difference between the reported use of anesthesia and sedation and respondents' preference for these treatment modalities. These data suggest that fear of dentistry is still prevalent and that patients who are fearful would seek oral health care more regularly if general anesthesia or conscious sedation were more readily available.

Adult↗

Resuscitation of the pediatric patient.

Fortunately, the incidence of pediatric cardiopulmonary arrest is extremely low in the outpatient dental office setting. Because most cardiopulmonary arrests in children result from a progressive deterioration in respiratory function, outcome critically depends on rapid diagnosis and evaluation of the adequacy of ventilation and the pediatric airway. This holds true for any pediatric medical emergency. Our goal must be instituting simple resuscitative measures before full cardiopulmonary arrest develops. Whatever the nature of the medical emergency, caring for a child under these circumstances is challenging. Pediatric Advanced Life Support (PALS) and continual review of the American Heart Association guidelines should be considered by those specializing in the treatment of infants and children. This training will not only bolster practitioner confidence, but enable prompt, effective response for any pediatric medical emergency.

Ambulatory Care↗

Thoughts on the management of chronic facial, head, and neck pain.

As previously stated in this paper, the therapeutic goal in the management of patients with chronic pain conditions in the face, head and neck is management and rehabilitation, striving for a 50 percent decrease in pain, a 50 percent increase in function and mobility, and a 50 percent decrease in medication with the elimination of agents with an addicting potential. These results will best be obtained through proper diagnosis and utilization of the aforementioned techniques in an interdisciplinary fashion as has been described.

Analgesics↗

Transcutaneous electrical nerve stimulation and myoneural injection therapy for management of chronic myofascial pain.

The purpose of this article has been to discuss in detail both the rationale and techniques for TENS and myoneural injection therapy as modalities for the management of chronic myofascial pain. In a more subtle sense, we have also interjected some of our philosophy regarding the treatment of chronic myofascial pain. As was discussed earlier in the text of this article, very seldom, if ever, will any single technique stand alone as a "cure" for the patient with chronic pain, but, instead, each modality must be considered as an adjunctive form of multidisciplinary care. The multidisciplinary approach to pain management includes, as a minimum, pharmacotherapy, physical therapy, and behavioral medicine therapy. The concept of the team approach and goals of management, rather than cure, for chronic myofascial pain, cannot be overstated and is often as difficult to impart to the clinician as it is to the patient. To employ any individual form of therapy, the clinician must understand the indications and limitations of each modality in a total treatment program. Over the last several years TENS therapy has become extremely popular to a large extent because it is a noninvasive technique that most patients can be taught to use safely and effectively. An additional advantage to TENS therapy is that it provides many patients with some means of control over their pain, independent of medications and hands-on therapy by health care providers. Myoneural block therapy is often utilized to add a measure of control over the severe pain and dysfunction that may be present during the early phases of active treatment of chronic myofascial pain. It is used to enhance the effects of a conservative multidisciplinary pain management program when utilized on a short-term basis. Myoneural block therapy is often a useful adjunct to physical therapy to improve the patient's overall range of motion and facilitate either treatment by the physical therapist or a home exercise program. The clinician is reminded that myoneural injection therapy can be overutilized. It should be limited as to the number of injections per visit. Also, the total number of visits the patient receives injections should be kept low. After the initial myoneural injection treatment series of three to five sessions, it should be utilized only for severe pain exacerbation that has been unresponsive to conservative, noninvasive management.

Anesthetics, Local↗

Appropriate selection of anesthesia personnel for office dental anesthesia.

The requirement for pain and anxiety control for dental patients has been estimated as high as 50 per cent of the population. Supporting this statement is the estimation that 35 million Americans avoid routine dental care until they are in severe pain. This amounts to 15 per cent of the American population and represents a significant public health problem. There is a long tradition of anesthesia provided in the dental office. This article will focus on the personnel who may provide services to dental patients requiring anesthesia.

Anesthesia, Dental↗

Hypotension in spinal anesthesia: a comparison of isobaric tetracaine with epinephrine and isobaric bupivacaine without epinephrine.

Two isobaric spinal anesthetic solutions (bupivacaine 0.5%/20 mg without epinephrine and tetracaine 0.5%/15 mg with 0.2 mg epinephrine) were compared in a double-blind study of 60 patients. Patients were injected while in the lateral recumbent position and were immediately turned supine and horizontal. Up to 30 min after injection, no differences were found between the groups regarding segmental level of analgesia, changes in heart rate, and onset to or maximum decrease in mean arterial pressure (MAP). No correlation was found between maximum decrease in MAP and level of analgesia. At time of maximum decrease in MAP (tetracaine group - 16.7 +/- 12.8% (mean + SEM), bupivacaine group -19.4 + 14.8%) the level of analgesia was significantly higher in the tetracaine group (T5-6) than in the bupivacaine group (T7-8). Hypotension occurred in five patients in the bupivacaine group and in six in the tetracaine group. Two patients in the tetracaine group (but none in the bupivacaine group) had bradycardia. Hypotension together with bradycardia was observed in one patient in the tetracaine group but in no patient in the bupivacaine group. Two patients in each group developed postlumbar puncture headache. The authors conclude that the choice of local anesthetic agent, by itself, is not the sole cause of hypotension seen with spinal anesthesia.

Anesthesia, Spinal↗

Pharmacotherapy for chronic facial pain.

The clinical usefulness of a drug therapy program for the management of chronic head and neck pain requires an understanding of the conditions in which the program will be used. The practitioner should remember that drug therapy is not the keystone of chronic pain management, but only a useful adjunct that should be eliminated or reduced as soon as feasible. The other various modalities for chronic pain management, which include physical therapy, relaxation therapy, transcutaneous electrical nerve stimulation, injection therapy, and occlusal reconstruction should be utilized to their fullest extent if the patient is to achieve success.

Analgesics, Opioid↗

Comparison of neural blockade and pharmacokinetics after subarachnoid lidocaine in the rhesus monkey. II: Effects of volume, osmolality, and baricity.

The effects of volume, osmolality, and baricity on lidocaine spinal anesthesia in the rhesus monkey were studied. Changes in neural blockade, physical properties of cerebrospinal fluid, and arterial pharmacokinetics associated with variations in injectate composition were assessed. Wide ranges of volume, baricity, and osmolality were studied using 1, 2, and 5% lidocaine prepared in either sterile water or 7.5% dextrose. Minimal changes in neural blockade were found in the ranges of osmolality and baricity studied, although 5% lidocaine in sterile water resulted in significantly shorter complete recovery times for both sensory and motor block when compared to other solutions. Samples of cerebrospinal fluid obtained after injection of lidocaine showed increases or decreases in specific gravity and osmolality depending on the physical properties of the solution injected. No differences in elimination phase pharmacokinetics were found with any of the lidocaine solutions. Rates of systemic absorption increased with decreasing osmolality. Osmotic potentiation of lidocaine spinal anesthesia could not be demonstrated.

Anesthesia, Spinal↗

Neural blockade and pharmacokinetics following subarachnoid lidocaine in the rhesus monkey. I. Effects of epinephrine.

A sensitive and reliable animal model for the objective physiologic and pharmacokinetic evaluation of spinal anesthesia has been developed. Using this model, spinal anesthesia using lidocaine (30 mg) in 7.5% dextrose with and without epinephrine was compared. Epinephrine did not alter the degree or duration of time to achieve maximum motor block. However, epinephrine did significantly increase the time for complete motor recovery. A significantly higher dermatome level of sensory block was achieved in the epinephrine-containing solutions, as well as a significantly longer time for complete recovery. This reflects a latent effect of epinephrine, as the time for two-segment regression was independent of epinephrine. Pharmacokinetic analysis showed no effect of epinephrine on absorption and elimination constants. The maximum plasma concentration and time to reach maximum plasma concentration were equal with and without epinephrine.

Anesthesia, Spinal↗

Ineffective ventilation during conscious sedation due to chest wall rigidity after intravenous midazolam and fentanyl.

Chest wall rigidity has been reported after the administration of high-dose intravenous fentanyl. This case report supports the observation that low-dose intravenous fentanyl may also cause chest wall rigidity. The treatment of chest wall rigidity with naloxone or neuromuscular blocking agents is controversial. A discussion of the management of fentanyl-induced chest wall rigidity is presented.

Adult↗