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Biomedical subjects

J C Pierson

Publications and source records attributed to J C Pierson.

9 recordsLinked to original sources

Cutaneous and visceral granulomas in common variable immunodeficiency.

A middle-aged woman with common variable immunodeficiency noted a papular skin eruption that simulated Gottron's sign of dermatomyositis on the dorsal hands. Examination of a skin biopsy specimen demonstrated noninfectious granulomatous inflammation. The patient was subsequently found to have visceral granulomas when examined using laparotomy. Noninfectious granulomas of the viscera and integument have been previously reported in patients with several immunodeficiency syndromes, including common variable immunodeficiency.

Adult↗

Pen push purpura: iatrogenic nail bed hemorrhages in the intensive care unit.

Peculiar fingernail hemorrhages appeared in a febrile, comatose patient several weeks after she was admitted to the hospital. Bedside questioning of the nursing staff uncovered a frequently used neurologic examination maneuver as the cause. We suggest the term "pen push purpura" to describe this phenomenon. The clinical significance and various causes of nail bed hemorrhages are reviewed.

Female↗