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Biomedical subjects

J C Pitts

Publications and source records attributed to J C Pitts.

6 recordsLinked to original sources

The natural history of patients with benign prostatic hyperplasia as diagnosed by North American urologists.

PURPOSE: We defined outcomes for men with a clinical diagnosis of benign prostatic hyperplasia. MATERIALS AND METHODS: We followed for 4 years 500 candidates for elective prostatectomy treated nonoperatively in 5 North American urology practices. RESULTS: There were 371 survivors with complete data at 4 years. Of 60 men with mild, 245 with moderate and 66 with severe baseline symptoms 10, 24 and 39%, respectively, had undergone surgery; 27, 31 and 27%, respectively, were on pharmacological therapy, and 63, 45 and 33%, respectively, were off active treatment at 4 years. Mild or moderate symptoms were noted at 4 years in 83, 59 and 23% of the patients, respectively, while 17, 41 and 77%, respectively, had severe symptoms or had undergone surgery. CONCLUSIONS: Outcomes for men with a clinical diagnosis of benign prostatic hyperplasia depend on initial symptom severity. However, the course of symptoms also varies among patients even with the same initial symptom severity.

Cohort Studies↗

Penetrating injuries of the ureter.

We reviewed 18 cases of penetrating ureteral injury encountered during a 10-year interval. Low velocity gunshot injuries occurred in 16 patients. All levels of the ureter were represented with near equal incidence. Stented ureteroureterostomy was the primary mode of management and had satisfactory results, with temporary urine leaks resolving spontaneously in 4 patients, responding to temporary catheter diversion in 1 and requiring reoperation in 2. Plastic stents were inferior to silicone or rubber materials. Colon and/or bowel injury was universal and was not found to justify alteration in the choice of surgical timing or technique, or to influence over-all results. Adequately drained urine poses no threat of cicatrical stenosis. Excretory urography is reliable and retrograde studies are dependable when urography is equivocal.

Adolescent↗

Penetrating injuries of the ureter.

Eighteen cases of penetrating ureteral injury encountered over 10 years are reviewed. Low-velocity gunshot was the mode of injury in 16. All levels of the ureter were represented with near-equal incidence. Stented uretero-ureterostomy was the primary mode of management, offering satisfactory results, with temporary urine leaks resolving spontaneously in four, responding to temporary catheter diversion in one, and requiring reoperation in two. Plastic stenting was inferior to silastic or rubber materials. Colon and/or bowel injury was universal and was not found to justify alteration in choice of surgical timing or technique, or to influence overall results. Adequately drained urine poses no threat to cicatricial stenosis. Urography is reliable; retrograde studies are dependable when urography is equivocal.

Adolescent↗