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Biomedical subjects

J C Quintyn

Publications and source records attributed to J C Quintyn.

13 recordsLinked to original sources

[Surgical treatment of inferior retinal detachment: advantages of postoperative traction of the right inferior muscle].

AIM: To evaluate the advantages of keeping the right inferior muscle in traction during external surgery for inferior retinal detachment. PATIENTS AND METHODS: This was a prospective study involving ten patients consecutively operated on for rhegmatogenous retinal detachment at the Toulouse-Rangueil Teaching Hospital. Internal plugging by air or a C2F6-air mixture was systematically performed, together with external indentation and total subretinal fluid puncture. At the end of surgery, a 2.0 silk thread was set beneath the right inferior muscle and kept in traction from the forehead for a few days. The patient was maintained feet up, in a dorsal decubitus posture. RESULTS: Results proved excellent, with ten anatomical successes. However, one patient had to have gas reinjected and in another subretinal fluid persisted for 3 months. DISCUSSION: The risk of surgical failure in inferior retinal detachment is greater because dabbing is more difficult to perform. To make this dabbing easier, we propose maintaining the ocular globe rearward by maintaining traction on the right inferior muscle, which produced excellent results. CONCLUSION: The technique proposed is easy to perform, and combined with internal dabbing and adequate patient positioning, it should help improve the surgical outcome of inferior retinal detachments.

Aged↗

[Specifications of retinal detachment surgery in highly myopic eyes of 10 or more dioptres and hemorrhagic complications: 79 cases].

INTRODUCTION: We report a series of 79 eyes undergoing primary surgery for rhegmatogenous retinal detachment associated with severe myopia greater than 10 diopters. Specific surgical procedures are recommended for these patients in order to minimize the high incidence of postoperative hemorrhagic complications. MATERIALS AND METHODS: Seventy-nine eyes of 76 patients treated for retinal detachment with severe myopia greater than 10 diopters were reviewed. Scleral buckling was performed in 21 eyes and pars plana vitrectomy in 58 eyes. RESULTS: After a mean follow-up period of 23.8 months, the final anatomical success rate was 93.7% (74 cases). Postoperative hemorrhagic complications (suprachoroidal hemorrhage and vitreous hemorrhage) occurred in four cases after scleral buckling and in ten cases after vitrectomy. DISCUSSION: In this study, primary scleral buckling for retinal detachment was less frequently performed than vitrectomy. Broad scleral buckling may not be associated with higher postoperative hemorrhagic complications, when the buckle does not extend over six clock hours. Postoperative hemorrhagic complications also occurred after vitrectomy; however, scleral buckling associated with vitrectomy does not seem to increase the complication rate. CONCLUSION: This retrospective study of 79 cases of rhegmatogenous retinal detachment with severe myopia higher than 10 diopters suggests that vitrectomy is often considered a primary procedure. Broad scleral buckling associated with vitrectomy is a safe and effective procedure, with an acceptable incidence of complications when not extending over six clock hours.

Choroid Hemorrhage↗

[Meningococcus endophthalmitis without meningitidis].

Meningococcus endophthalmitis is exceptional. We report a case of ocular damage following type C meningococcus septicemia with no meningitis. A 20-year-old man reported to the emergency unit for polyarthritis pain in various joints, associated with chills, nausea, and diarrhea without fever. Ophthalmological examination revealed uveitis. A few days later, endogenous endophthalmitis was suggested because of a worsening general condition and fever spells to 39 degrees C. A hemoculture sampled on the patient's admission 4 days earlier revealed Neisseria meningitidis positivity. Meningococcus septicemia with no meningitis was diagnosed. Before the introduction of antibiotics, meningococcus meningitis was unfortunately frequent and ocular septic embolism was not a rare occurrence. The diagnosis of meningococcemia was delayed in our patient because of the atypical symptomatology and ocular manifestations in the forefront. As with any endogenous endophthalmitis, prognosis is bleak and it should be raised whenever suspected uveitis does not react to standard treatment.

Adult↗

Concentration of neuron-specific enolase and S100 protein in the subretinal fluid of rhegmatogenous retinal detachment.

BACKGROUND: Neuron-specific enolase and S100 protein are markers of neuronal lysis. To assess the neuronal suffering in rhegmatogenous retinal detachment we quantified neuron-specific enolase and S100 protein in the subretinal fluid. METHODS: The puncture was performed in the sclera with a Merseture 5/0 round needle, and the fluid was collected with a glass capillary tube. Twelve subretinal fluid samples were obtained from 12 eyes with rhegmatogenous retinal detachment undergoing retinal detachment surgery. Vitreous from ten eyes with macular hole or epimacular membrane served as negative control group, and vitreous collected during cornea procurement from ten deceased patients served as positive control group. RESULTS: The mean concentration of neuron-specific enolase (in nanogrammes per millilitre) was 602 in the subretinal fluid of rhegmatogenous retinal detachment, 10.2 in the serum of these patients, 2.9 in the vitreous of the negative control group, and 364 in the positive control group. The mean concentration of S100 protein (in nanogrammes per millilitre) was 104 in the subretinal fluid of rhegmatogenous retinal detachment, <0.1 in the serum of these patients and in the vitreous of the control negative group, and 11.18 in the positive control group. CONCLUSION: Neuron-specific enolase (NSE) and S100 are known to be good markers of brain stress and, thus, are good markers of retinal stress.

Adult↗

[Final visual acuity in patients undergoing posterior vitrectomy for Terson's syndrome: a series of 11 cases].

PURPOSE: The purpose of this study was to assess visual acuity after vitrectomy for Terson's syndrome. METHODS: This is a retrospective study of 11 eyes (7 patients), who underwent pars plana vitrectomy between 1996 and 1998. Visual acuity was evaluated at 1, 5 and 12 months. We also report immediate and delayed complications. RESULTS: Initial visual acuity was below 20/200 for 9 patients (81%). Final visual acuity was 20/25. An epiretinal membrane was noticed in two patients during the surgical procedure. Final visual acuity for those two patients was only 20/40 and 20/100. Two patients developed cataract following vitrectomy, one developed an endophthalmitis with good vision recovery. CONCLUSION: Vitrectomy for vitreous hemorrhage in Terson's syndrome after three months follow up is a solution without major risks and has a good visual prognosis. Final visual acuity of patients after vitrectomy for Terson's syndrome is good. However, Terson's complications such as epiretinal membrane and cataract are limiting factors for good visual recovery.

Adult↗

Effects of low alcohol consumption on visual evoked potential, visual field and visual contrast sensitivity.

PURPOSE: We studied changes in the vision of 16 people after consumption of a small quantity of alcohol, at a blood alcohol level (BAL) of 0.57 g/kg. METHODS: We studied visual contrast sensitivity (VCS) using Vistech VCTS 6500, visual evoked potential (VEP) by checked pattern stimulations and the peripheral visual field (PVF) with a perimetric automatic Humphrey. We first carried out the tests on sober people and then on individuals with a BAL of 0.57 g/kg. RESULTS: Alcohol consumption caused no significant difference in performance for these 3 tests. However, at a BAL of 0.57 g/kg there was a decrease in cerebral function, as shown by an increase in the number of mistakes made in the Wisconsin Card Sorting Test. CONCLUSION: These results suggest that for a low blood alcohol level, visual performance is less affected by the visual changes than by alteration in brain functions.

Adult↗

Orbital sinus histiocytosis (Rosai-Dorfman disease): a lacrimal gland involvement.

We report the clinical and histopathological features of 2 cases of orbital Rosai-Dorfman disease with lacrimal gland involvement but no lymphadenopathy or cutaneous involvement. The first case was a 7-year-old boy, who was referred to the ophthalmology department with a proptosis in the left eye. The second case involved a 57-year-old African man, who developed oedema of the right upper eyelid over a 4-month period. Ocular involvement in Rosai-Dorfman disease is rare (10%). The diagnosis is histological in combination with immunohistology and is often delicate, especially in extranodal localizations. Histopathologically, normal gland morphology was altered by fibrosis and inflammatory cells. To our knowledge, this is the first report on lacrimal involvement in incomplete, thus uncommon sinus histiocytosis with massive lymphadenopathy.

Child↗

Comparison after 10 years of two 100-patient cohorts operated on for eviscerations or enucleations.

PURPOSE: To compare the indications, surgical techniques, and operative outcome between two 100-patient populations operated on for evisceration or enucleation with a 10-year interval. METHODS: This retrospective study involved 100 patients operated on between 1987 and 1990 (Group 1) compared with another 100 patients operated on between 1996 and 2000 (Group 2). Group 1 included 64 males and 36 females, mean age 49 years; Group 2 included 60 males and 40 females, mean age 53. RESULTS: In Group 1, 19 eviscerations were performed, versus 55 in Group 2. In both groups, half of the indications for surgery were a painful blind eye. In Group 1, endophthalmia (23%) came second, whereas it was trauma (15%) in Group 2. Sixty-eight patients were implanted in Group 1 (silicone spheres 69%) versus 86 in Group 2 (hydroxyapatite spheres 69%). Twenty spheres (20%) were rejected in Group 1 versus 7% in Group 2. DISCUSSION AND CONCLUSIONS: The proportion of eviscerations increased in 10 years. The number of endophthalmitis-related operations decreased and trauma-related operations increased. The number of implantations increased with hydroxyapatite as the first choice material instead of silicone. This most likely contributed to reducing the number of rejections.

Adolescent↗