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Biomedical subjects

J C Ramseyer

Publications and source records attributed to J C Ramseyer.

13 recordsLinked to original sources
PubMed1977

Acute infantile motor unit disorder. Infantile botulism?

Eight infants with an acute reversible motor unit disorder are described, including two infants from whom Clostridum botulinum type A was isolated from stool specimens. The clinical spectrum includes constipation, cranial nerve deficits, pupillary involvement, and generalized hypotonic weakness. There were no deaths, and all infants have had complete clinical recovery. A characteristic electromyographic (EMG) pattern was present in part until clinical recovery. This distinctive pattern consisted of brief, small, abundant for power exerted motor unit potentials. This EMG pattern in the context of the clinical syndrome may well be diagnostic for acute infantile motor unit disorder.

Acute Disease↗
PubMed1977

The orbicularis oculi reflex: pathologic studies in childhood.

The orbicularis oculi reflex was studied in 12 children with intrinsic brain stem gliomas and in six children with other posterior fossa pathology. The results were compared with previously established childhood normal values. Seventy-eight percent of the children demonstrated a pathologic alteration of the reflex comparable to reported results in adult patients. The orgicularis oculi reflex test in childhood in a relatively simple and risk-free procedure in the evaluation of brain stem disease in childhood.

Adolescent↗
PubMed1976

The orbicularis oculi reflex in infancy and childhood. Establishment of normal values.

The orbicularis oculi reflex and direct facial nerve conduction were studied in 38 normal children ranging in age from 1 month to 9 years. Direct facial nerve conduction in all groups was within adult normal values. The early response of the orbicularis oculi reflex obtains normal adult values by age 24 months. Both ipsilateral and contralateral delayed responses are absent under 20 months, are widely variable between 21 and 56 months, and obtain adult normal values beginning at age 6 years. The expression of the orbicularis oculi reflex is an age-related phenomenon presumably reflecting brain stem anatomic and functional maturation.

Age Factors↗
PubMed1967

Management of transient cerebral ischemic attacks.

Transient ischemic attacks (TIAs) are brief reversible episodes of neurological dysfunction due to temporary focal cerebral ischemia. Angiography should be performed only when operation is indicated or when the diagnosis is in doubt. Surgical treatment is recommended when the patient is a good surgical risk, when the stenosis is more than 70 per cent in the appropriate vessel and in certain patients with less severe stenotic lesions that appear to be a probable source of emboli. Anticoagulant therapy is indicated when there are recurrent TIAs, when the patient is not a good surgical candidate and when no appropriate surgically remediable lesion is found by angiography. If there is any significant contraindication to anticoagulants they should not be given. Discontinuance of anticoagulant therapy when the patient has been symptom-free for six months is recommended. In the experience of the authors the TIA syndrome is more benign in its course than was originally suspected and a conservative approach to surgical and anticoagulant therapy is recommended.

Aged↗