Biomedical subjects
Publications and source records attributed to J C Rieser.
Three patients with Meibomian gland carcinoma were treated initially with irradiation. This therapy was palliative in one case that eventually required orbital exenteration because of recurrent disease. A second patient was clinically tumor-free ten months after treatment when he died of a myocardial infarction. The third patient has shown no evidence of recurrent disease in the 25 months since treatment.
An improved technique for high-contast, high-resolution fluorescein angiography of the optic disc has been developed that almost eliminates pseudofluorescence. Fluorescein angiography of the optic disc was performed on normal, ocular hypertensive, and glaucomatous patients. Rapid-sequence angiograms in the early arterial phases have demonstrated localized areas of hypofluorescence or filling defects of the optic disc. Two types of fluorescein filling defects were observed-absolute and relative. The number of absolute filling defects, which increased with degree of visual field loss, was greater in glaucomatous than in ocular hypertensive or normal eyes. Similarly, ocular hypertensive eyes showed a larger number of discs with filling defects than normal eyes. It is postulated that relative defects progress to absolute filling defects, which may be an indication of impending loss of visual field.