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Biomedical subjects

J C Scatarige

Publications and source records attributed to J C Scatarige.

36 records · Page 2Linked to original sources

Actinomycosis: CT findings in six patients.

Actinomycosis is an uncommon disease with clinical and radiographic findings that overlap those of other inflammatory and neoplastic conditions. A retrospective review of CT scans in six proved cases revealed a spectrum of findings, including soft-tissue mass with various degrees of infiltration and abscess formation. Administration of IV contrast material was helpful in defining the loculations of the abscess in two cases. Areas of involvement included the neck (two cases), liver (one case), abdominal wall (one case), thorax (one case) and kidney and retroperitoneum (one case). CT findings of a soft-tissue mass in the neck, lungs, or abdomen, with or without a draining sinus or fistula, raise the possibility of actinomycosis in patients with clinical findings that suggest a subacute or chronic inflammatory process.

Actinomycosis↗

Cryptosporidiosis of the gastric antrum: detection using CT.

We describe a patient who had cryptosporidiosis and cytomegalovirus infection of the gastric antrum that was initially detected on computed tomography (CT) scans. CT may be useful in the evaluation of immunocompromised patients with diarrheal illness, as well as in the assessment of the gastrointestinal tract.

Acquired Immunodeficiency Syndrome↗

Low-attenuation thoracic metastases in testicular malignancy.

Low-density abdominal and pelvic lymph nodes are seen in nearly half of patients with testicular cancers. Thoracic low-attenuation metastases are much less common. Three cases of low-density metastases to lung parenchyma and mediastinal nodes are presented. In a man of appropriate age, a low-attenuation pulmonary or mediastinal mass should prompt a search for a primary testicular neoplasm.

Adult↗

Transdiaphragmatic extension of invasive thymoma.

The initial and follow-up computed tomographic (CT) examinations of 19 patients with surgically proven invasive thymoma were reviewed; 10 have been previously reported. Transdiaphragmatic extension of tumor was observed in six (31.5%) of the 19 patients. Sites of infradiaphragmatic invasion included the right lateral liver surface, posterior pararenal space, left paraaortic region, perigastric soft tissue, and spinal canal. In the patient with known or suspected invasive thymoma, transdiaphragmatic extension is a common occurrence that requires routine CT imaging of the upper abdomen to avoid underestimating the extent of disease.

Adult↗

CT demonstration of postanginal sepsis.

A case of postanginal sepsis is presented with a brief discussion of the pathogenesis and presentation of the syndrome. CT scanning can effectively delineate the parapharyngeal inflammatory process, extension along fascial planes, internal jugular vein encroachment and thrombus, as well as septic emboli complications.

Adult↗

Fatty infiltration of the liver: ultrasonographic and computed tomographic correlation.

To evaluate the accuracy of ultrasonography in diagnosing fatty infiltration of the liver (FIL), the authors compared gray-scale B-mode ultrasonography and unenhanced computed tomographic (CT) liver images in a study of 47 patients. The CT scans, which served as the diagnostic standard, were classified as normal, Grade 1 (mild FIL), Grade 2 (moderate FIL), and Grade 3 (severe FIL). Applying predetermined sonographic textural criteria, two experienced radiologists independently graded each ultrasound study for the presence and severity of FIL. The overall accuracy of ultrasonography in detecting FIL was 85 per cent, with 100 per cent sensitivity and 56 per cent specificity. The sonographic/CT correlation in grading the severity of FIL was particularly good for Grade 2 and Grade 3 FIL. Ultrasound is a sensitive and reasonably accurate diagnostic tool in assessing fatty infiltration of the liver.

False Positive Reactions↗

Computed tomography of calcified liver masses.

Our retrospective study of 230 computed tomographic (CT) studies of hepatic masses yielded 28 cases (12.2%) which contained calcification. Calcific deposits were noted in 9 of 59 patients (15.3%) with hepatocellular carcinoma (HCC), 15 of 82 patients (18.3%) with liver metastases from colorectal carcinoma (MCRC), 2 of 71 patients (2.8%) with noncolonic liver metastases, and 2 of 18 patients (11%) with a benign liver mass. The patterns of calcification in HCC and MCRC were highly variable and exhibited some overlap. Although the CT demonstration of calcification in HCC and MCRC is not uncommon, particularly in patients who have undergone radiotherapy or chemotherapy, we could identify no specific diagnostic pattern.

Adenocarcinoma↗

Computed tomography of endometriosis.

Six examples of pelvic masses due to endometriosis were detected by computed tomography (CT) in a group of women aged 30-43. Lower abdominal or pelvic pain was the chief complaint in four cases. The ileum and rectosigmoid were routinely opacified with contrast material prior to examination. Endometriosis exhibited a variety of findings including a constricting rectosigmoid mass, a lesion of the pelvic side wall, bowel wall implants, and posthysterectomy pelvic masses. There was no standard CT density; the lesion near the pelvic side wall appeared solid, one cul-de-sac mass appeared solid, and a second had a mixed cystic and solid appearance. Discrete adnexal endometriosis appeared as thick-walled cystic masses (two cases) or as a simple cyst (one case). Bowel wall involvement and the pelvic side wall lesion were not successfully identified by ultrasound. It is concluded that CT can play a role in the diagnosis of endometriosis.

Adult↗

Low attenuation nodal metastases in testicular carcinoma.

Abdominal and thoracic computed tomography examinations were abnormal in 23 of 57 patients (40.5%) with seminomatous and nonseminomatous testicular tumors. Lymph node metastases measuring less than 30 Hounsfield units (HU) occurred in 10 of these 23 patients (43.5%), five with seminoma, four with mixed germ cell tumors, and one patient with embryonal cell carcinoma. Biopsy material was obtained from low attenuation metastases in four patients. Three patients who had completed chemotherapy had evidence of extensive necrosis, but two of three had persistent tumor. In the fourth patient, a case of untreated mixed germ cell tumor, there were numerous small epithelial-lined cystic spaces. Biopsies from five patients with nodal masses measuring greater than 30 HU showed no necrosis or cystic change. There was no significant correlation between the attenuation characteristics of the metastases and clinical activity of the tumor.

Adult↗

The sonographic "scar sign" in focal nodular hyperplasia of the liver.

The sonographic features of focal nodular hyperplasia of the liver as reported in the literature and nonspecific. However, a linear cluster of bright echoes was detected in the nodules of two of our patients with surgically proven focal nodular hyperplasia. Pathologically this finding correlated closely with the gross appearance of the characteristic fibrotic scar of focal nodular hyperplasia. When present, this "scar sign" should suggest the diagnosis of focal nodular hyperplasia, particularly in the typical clinical setting.

Adult↗

Left adrenal vein localization by 3D real-time volume-rendering CTA before laparoscopic nephrectomy in living renal donors.

BACKGROUND: We investigated whether the left adrenal vein could be consistently localized on three-dimensional (3D) real-time volume-rendering computed tomographic angiographic (CTA) mapping in a group of living renal donors before laparoscopic nephrectomy. METHODS: Sixty-six consecutive potential renal donors were referred for CTA vascular mapping before laparoscopic donor nephrectomy. Thirty-three patients were examined on a single-detector helical CT scanner and the other 33 were examined on a multidetector unit. In each patient, arterial phase and venous phase volumetric data sets were acquired after the intravenous injection of 150 cc of non-ionic contrast material. Three radiologists reviewed the data sets at a free-standing workstation after the application of 3D volume-rendering software and reached a consensus on whether the left adrenal vein was visualized and, when seen, its position relative to the abdominal aorta. RESULTS: The left adrenal vein was found in 92.5% of the 66 donors (91% in the single-detector group and 94% in the multidetector group). The junction of the left adrenal vein and left renal vein averaged 5.2 mm (range = 0-13 mm) from the left lateral wall of the abdominal aorta. CONCLUSION: Three-dimensional real-time volume-rendering CTA with single-detector and multidetector scanners permits consistent localization of the left adrenal vein in more than 90 % of prospective living renal donors.

Adrenal Glands↗

Distribution of metastases in breast carcinoma: CT evaluation of the abdomen.

To determine the frequency and distribution of extrahepatic and extraskeletal metastases in patients with breast carcinoma, the abdominal CT scans of 260 consecutive patients were systematically evaluated. Extrahepatic and extraskeletal metastases were demonstrated in 26 patients (10%). Confirmation of findings was made by biopsy, autopsy, or by demonstration of progression or regression of disease. Twelve patients (4.6%) demonstrated metastases to the stomach, eleven of whom presented with a linitis plastica pattern. Retroperitoneal and/or mesenteric adenopathy was noted in 10 patients (3.8%), of whom three demonstrated associated hydronephrosis and one demonstrated associated biliary obstruction. Ascites was seen in 14 (5.4%) and peritoneal carcinomatosis in 7 (2.6%). Genitourinary involvement included metastases to the kidney (one case), ureter (one), and uterus (one). Direct invasion of the diaphragm by adjacent pleural metastases (two cases) as well as a soft tissue metastasis (one case) was also demonstrated. Metastases to the ovaries, adrenals, or pancreas could not be identified. Although lesions to the liver and skeleton account for the largest group of metastases from breast carcinoma seen in the abdomen, one should be aware of the potential for other locations of metastatic disease.

Abdominal Neoplasms↗

Gastric leiomyosarcoma: CT observations.

The abdominal CT examinations of seven patients with gastric leiomyosarcoma (GLMS), proven by surgical or endoscopic biopsy or both in five patients and percutaneous aspiration biopsy in two, are reviewed. In the six patients studied prior to therapy, CT demonstrated that each of the primary gastric tumors was spherical or ellipsoidal, large (mean diameter 15 cm), and predominantly exogastric in location. Additional CT features of the primary tumor included necrosis in all six masses, a distinct gastric mural attachment in four, bubbles of gas or an air-fluid level or both in three, and mucosal ulceration in two. Direct tumor invasion of nearby organs was suggested by CT in four of the six patients, the spleen and pancreas representing the most frequent sites. Intraperitoneal spread of tumor was present in two patients; necrotic liver metastases accompanied three of the six primary tumors and were found in an additional patient examined 4 years after gastric resection. By accurately reflecting the biological behavior of GLMS, CT is an ideal imaging modality for studying this unusual neoplasm. Differential diagnosis and specificity of the CT findings are discussed.

Adult↗

Three-dimensional volume-rendering CT angiography in vasculitis: spectrum of disease and clinical utility.

Spiral computed tomographic angiography (CTA) coupled with three-dimensional volume-rendering image processing is a less invasive alternative to conventional catheter angiography. The technique has been used successfully in a variety of vascular diseases. In this pictorial essay, we review the CTA findings in selected cases of vasculitis. Technical considerations and the potential clinical value of this method are discussed.

Adult↗

Visual survey of cancer dissemination: classic patterns on helical CT. Abdomen and pelvis.

Helical CT evaluation of the abdomen and pelvis can be challenging in the cancer patient. This pictorial essay illustrates the important sites of neoplastic dissemination in the abdomen and pelvis. We will emphasize the classic CT appearance of several selected sites and indicate, where appropriate, the primary lesions usually associated with each.

Abdominal Neoplasms↗