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Biomedical subjects

J C Scharfenberg

Publications and source records attributed to J C Scharfenberg.

12 recordsLinked to original sources
PubMed1995

Eyelid microcystic adnexal carcinoma.

Microcystic adnexal carcinoma is an uncommon cutaneous tumor with multiple synonyms. On cursory microscopic examination, the tumor mimics syringoma and other benign skin adnexal tumors. However, the asymmetric, infiltrative growth pattern clearly sets the lesion apart as carcinoma. The tumor is locally aggressive, with recurrences common, but regional metastases are rare. Histogenesis is controversial. Optimal treatment consists of complete surgical excision with clear surgical margins.

Adult↗
PubMed1995

Lung transplantation in Louisiana: report of the first twenty lung transplants performed in the state.

Lung transplantation is a successful alternative treatment for a variety of end-stage lung diseases. The first 20 lung transplants performed in Louisiana between November 1990 and July 1994 are reported from Ochsner Foundation Hospital. Transplant procedures included 1 heart-lung, 11 bilateral sequential lung, and 8 single-lung transplants in 8 males and 11 females (1 retransplantation). The average age was 38 years (range 7-60), and the median waiting time was 34.5 days (range 1-329). Indications for transplant included emphysema, pulmonary fibrosis, pulmonary hypertension, cystic fibrosis, bronchiectasis, and bronchiolitis obliterans. Overall 1-year and 3-year survival were 65.0% and 58.5%, respectively. Infection was the major cause of morbidity and mortality. Rejection episodes were observed but treated successfully in all 20 patients. Lung transplantation has proved to be a successful treatment for a variety of severely limiting and terminal pulmonary conditions for patients in our state.

Adolescent↗
PubMed1988

Orbital angiolipoma.

Successful resection of an orbital angiolipoma in a 3-year-old child was performed. To our knowledge, this is the first report of angiolipoma in this site.

Child, Preschool↗
PubMed1985

Multicentric müllerian squamous neoplasia.

Pure squamous neoplasia of the uterine corpus and uterine tube is explained by two possible mechanisms termed horizontal spread and vertical proliferation. We have reported a case of epidermoid carcinoma in situ of the uterine tube exemplifying the latter.

Carcinoma in Situ↗
PubMed1984

Persistent renal blastema in an adult.

To the authors' knowledge, this is the first reported case of any form of nephroblastomatosis occurring in an adult. Such a lesion is the presumed precursor of the rare Wilms' tumors that arise in adults.

Age Factors↗
PubMed1976

Monomorphic adenomas of salivary glands. Trabecular-tubular, canalicular, and basaloid variants.

Eleven cases of monomorphic adenoma of the salivary glands are interpreted as variants of pleomorphic adenomas (mixed tumors) that lack chondroid or myxomatous components. Nine of these tumors were in the parotid gland and two were on the hard palate. Monomorphic adenomas are usually encapsulated and frequently are partially cystic. Their histologic pattern may be confused with that of adenoid cystic carcinoma, but they grow in an expansile fashion and usually are monolobular. Histologically, they may be divided into trabecular-tubular, canalicular, and basaloid variants. Morphologically, they bear a resemblance to basaloid sweat-gland tumors (eccrine spiradenoma and cylindroma).

Adenoma↗