PubMed Health⌕ Search

Biomedical subjects

J C TURNER

Publications and source records attributed to J C TURNER.

At least 19 recordsLinked to original sources

Red cell lipids.

Explore the source record for details and available documents.

Erythrocytes↗

Absence of lecithin from the stromata of the red cells of certain animals (ruminants), and its relation to venom hemolysis.

Lipide extracts of the red cells of several animal species have been analyzed chromatographically. Genetically determined differences in phospholipide composition were found. Lecithin is absent from the cells of ox, sheep, and goat. Cells containing lecithin are susceptible to the direct hemolysin of cobra venom while cells not containing lecithin are resistant. The facts indicate that the direct hemolysin is a lecithinase.

Animals↗

On the relation of white blood cells and platelets to venom hemolysis.

Removal of the white cells and platelets from suspensions of red cells usually produces substantial reduction in the hemolytic activity of venoms. Guinea pig red cells constitute a notable exception and may be lysed by a direct action of venom. White blood cells and platelets appear to contribute to hemolysis by serving as sources of phosphatides for the formation of lysophosphatides. No correlation could be found between phospholipase activity and direct hemolytic activity of venoms. A recently described method (8) of paper chromatographic separation of phospholipides has been used successfully in part of the work.

Blood Platelets↗