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Biomedical subjects

J Callens

Publications and source records attributed to J Callens.

At least 19 recordsLinked to original sources

[Dermo-hypodermic lymphoid pseudotumors with follicular hyperplasia. Apropos of a case].

We report the case of a female patient with ubiquitously distributed cutaneous and subcutaneous nodules measuring 2 to 6 cm along their long axis. These nodules first developed at the age of 63 years and subsequently appeared in crops separated by spontaneous remissions. Studies of removed nodules demonstrated diffuse lymphoid follicular hyperplasia suggesting a tumor and raising difficult nosologic problems, especially regarding relationships with the extranodal multicentric Castleman syndrome. In march 1987, biopsy of a large scapular nodule spreading into the striated muscle suggested possible transformation into a low grade malignant lymphoma of the lymphoplasmocytoid type.

Biopsy↗

[Unexpected effect of repetition of imaged behavior].

In order to examine the efficiency of covert behavior rehearsal, 33 subjects, randomly assigned to three groups, were submitted to a task in a social condition. To reduce the stress-induced anxiety, the participants of the first group had been prepare by covert behavior rehearsal in a relaxed condition. Those of the second group received only relaxation and the third group had no preparation at all. The behavior rehearsal had no positive effect on the efficacy of the task execution. Moreover, a negative influence appeared. The results are discussed.

Adult↗

Excess costs related to non-steroidal anti-inflammatory drug utilization in general practice.

Data concerning the reasons for consultation and the use of NSAIDs were collected in 4643 patients, seen by 126 GPs over 2 days' consultation. In all, 11.6 per cent took NSAIDs. They were older (49 vs. 46 years, p = 0.02), took more drugs (3 vs. 2.5, p < 0.01), and more had ADRs (8 vs 2 per cent) than non-users, even after correction for age, sex and number of drugs taken. Some 33 per cent of NSAID users also took adjuvant medication for the prevention of gastric injury (including with COX-2 inhibitors meloxicam, nimesulide). Estimated excess costs associated with NSAID use were high, related to excess consultations (GP or specialist, for ADRs, approx. 5-8 million Euros per year in France) and to use of preventive medication (100 million Euros per year at least).

Adult↗