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Biomedical subjects

J Cano-Parra

Publications and source records attributed to J Cano-Parra.

7 recordsLinked to original sources
PubMed1999

Antibacterial and antifungal effects of soft contact lens disinfection solutions.

AIMS: To study the antibacterial and antifungal effects of soft contact lens disinfection solutions. METHODS: Eight contact lens disinfection solutions containing hydrogen peroxide or biguanides or polyquad compounds were evaluated with respect to their ability to disinfect a saline solution experimentally contaminated with different bacteria and with a fungus. We used cultures in blood Agar, MuellerHinton agar and Saboureaud's agar to identify the bacterial and fungal growth following 14 h of exposure to the disinfection solutions. RESULTS: Hydrogen peroxide, DYMED and polyhexamide solutions prevented the growth of the four bacteria studied. The solution containing biguanide prevented the growth of Escherichia coli and Staphylococcus epidermidis. The solution with polyquad solution only prevented the growth of Staphylococcus epidermidis and none of the disinfection solutions prevented the growth of Candida albicans. The control solution, which was saline, did not prevent the growth of either bacteria or fungi. CONCLUSIONS: Disinfection solutions containing hydrogen peroxide, or DYMED or polyhexamide can disinfect these four bacteria but none of them prevented the growth of Candida albicans.

Journal Article↗
PubMed1996

Goldmann applanation tonometry using sterile disposable silicone tonometer shields.

PURPOSE: Placement of a sterile single-use cover over the tonometer tip may be a convenient and safe alternative method to repeated chemical disinfection. This study was undertaken to evaluate the accuracy and performance of Goldmann applanation tonometry using a sterile disposable silicone tonometer shield over the biprism tip. METHODS: The same investigator measured intraocular pressure in 120 eyes with and without the shield. The eyes were tested randomly first with either the uncovered or the covered tonometer to control for the possible effects of repeated tonometry influencing measurement differences. Readings were recorded independently in a masked fashion. RESULTS: The intraocular pressure measurements evaluated with the silicone shield caused an average overestimation of the true intraocular pressure of 1.9 +/- 1.9 mmHg (P = 0.0001). Covered and uncovered readings correlated well (r = 0.91, P = 0.0001). The sensitivity and specificity of the covered tonometry in detection intraocular pressures of 21 mmHg or higher (as measured without the shield) were 96.3% and 68.8%, respectively. Minor distortions of the normal-appearing fluorescein bands were seen in 5% of the tonometries, and the shield had to be replaced because of bubbles or wrinkles on the applanating surface in 3.3% of the measurements, which means that care must be taken when fitting the shield. CONCLUSIONS: Although covered and uncovered tonometry readings correlated well, an overall trend for a slightly increased measured intraocular pressure as a result of using the silicone shield over the Goldmann tonometer tip was found. The outstanding sensitivity of this procedure in detecting increased intraocular pressure suggests that it can be useful in screening for ocular hypertension and glaucoma.

Adolescent↗
PubMed1995

Prospective trial of intraoperative mitomycin C in the treatment of primary pterygium.

AIMS: A prospective, randomised, double blind, placebo controlled study of intraoperative mitomycin C as adjunctive treatment of primary pterygium was conducted. METHODS: A total of 66 eyes of 54 patients with primary pterygium were treated with excision, with or without a single intraoperative application of mitomycin C (0.1 mg/ml for 5 minutes) to evaluate the efficacy and toxicity of this adjunctive treatment. The mean follow up was 14.1 months (range 12-23 months). RESULTS: Of the 36 eyes that underwent simple excision, 14 (38.8%) exhibited recurrences whereas only one of 30 eyes (3.33%) treated with excision and intraoperative application of mitomycin C had recurrence (p = 0.0006). Neither serious ocular complications nor systemic toxicity were noted in the mitomycin C treated group. CONCLUSION: Intraoperative mitomycin C appears to be an effective and safe adjunctive treatment of primary pterygium.

Adult↗