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Biomedical subjects

J Castillo

Publications and source records attributed to J Castillo.

At least 253 records · Page 14Linked to original sources

Comparative activity of cefotetan against plasmid-encoded aminoglycoside-resistant enterobacteria strains.

304 strains of R-plasmid harbouring enterobacteria resistant to aminoglycosides were studied for their susceptibilities to a range of antibiotics, including cefotetan. Cefotetan and latamoxef were the most active of the four cephamycins tested and all were stable to the beta-lactamases produced by these strains. No new beta-lactamases (SHV-2, CTX-1, TEM-4, CAZ-1) were found in these strains capable of hydrolysing third generation cephalosporins. The activity of cefotetan against these multi-resistant, beta-lactamase producing strains may be of clinical value.

Aminoglycosides↗

Aminoglycoside-phosphotransferases APH(3')-IV and APH(3") synthesized by a strain of Campylobacter coli.

Campylobacter coli strain 981 of animal origin was resistant to erythromycin, tetracycline, streptomycin, kanamycin, ribostamycin, neomycin, paromomycin, lividomycin, and butirosin. Resistance to aminoglycosides of strain 981 was mediated by phosphotransferases APH (3') type-IV and APH (3"). C. coli 981 harboured three plasmids of 24, 34, and 40 Megadaltons respectively. None of these plasmids were transferable to Escherichia coli K-12 by conjugation.

Aminoglycosides↗

[Digestive complications of Campylobacter enteritis].

Fifty children with acute diarrhoea, in which the only germ found in stools was Campylobacter fetus jejuni, are studied. Digestive complications occurred are discussed. Nine (18%) had lactose malabsorption, associated in two (4%) with saccharose malabsorption and in one (2%) with cow's milk protein intolerance. All complications were temporary, and carbohydrate malabsorption disappeared between one and three months.

Campylobacter Infections↗

[Campylobacter enteritis].

Authors report results of the study of a series of 50 children patients with Campylobacter enteritis. After insisting on the present frequency of this infectious agent as pathogen for human beings, they analyse the epidemiologic, clinic and therapeutic aspects.

Anti-Bacterial Agents↗