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Biomedical subjects

J Celdrán Gil

Publications and source records attributed to J Celdrán Gil.

At least 19 recordsLinked to original sources

[Effects of muscle training on breathing pattern in patients with severe chronic obstructive pulmonary disease].

OBJECTIVE: During physical exertion, the ventilatory response of patients with severe chronic obstructive pulmonary disease (COPD) is more rapid and shallow than that of healthy subjects. There is evidence that exercise training can alter breathing pattern in COPD patients. The purpose of the present study was to observe the effects of physical training on patients with severe COPD and to determine whether or not any possible changes were maintained over time. MATERIAL AND METHODS: Patients with severe COPD without bronchial reversibility were enrolled in a randomized controlled trial of a peripheral muscle training program carried out in a hospital setting. All enrolled patients were clinically stable, without exacerbation, and were randomly assigned to a training program of high (group A) or low (group B) intensity. RESULTS: Thirty-five men with severe COPD in stable condition (mean [SD] forced expiratory volume in 1 second at 41%[7%]) were enrolled in the study. The mean age was 64(5) years. Group A underwent training at 70(22) W and group B at 35(10) W, such that the estimated total work was 8050(2882) kJ in group A and 4044(1205) kJ in group B. Breathing pattern changes were detected in exercise tests only for group A patients, but the changes were not maintained 12 months after the end of the program. CONCLUSIONS: Intense training produces changes in the breathing pattern of patients with severe COPD. The changes are not specific to the task performed, not dependent on lactate production, and not maintained over the long term.

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[Community-acquired pneumonia in inpatients: mortality, comorbidity and risk classes].

BACKGROUND: It is necessary to determine what patients with community acquired pneumonia (CAP) are at highest risk of death and which characteristics allow such determination. OBJECTIVE: To analyze the risk classes in the CAP. To verify what was the associated comorbidity and whether age, sex or residence area of inpatients with CAP increased the proportion of deceased patients. METHODS: A total of 113 patients were studied (68 males and 45 females) and 15 died (13.3%). The mean age of the deceased patients was 82.5 years (standard error [SE]: 6.63 years) significantly higher than that in survivors (70.5 years, SE: 17.3 years). There were no significant differences concerning age or sex between the deceased patients and survivors belonging to the most severe class. Most patients had comorbidities (82 patients, 72.6%). Seventeen (15%) of the inpatients came from a nursing home, more frequently among the deceased (5 patients, 33%) than among survivors (12 patients, 12%), a statistically significant difference (p < 0.05). CONCLUSIONS: No differences were observed between patients regarding age or sex, once patients were stratified by risk classes. There was a high proportion of concomitant diseases, and the mortality rate was higher among patients with some associated disease. In our series, patients from a nursing home had a higher mortality rate.

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[Pneumonia in the elderly. Patients living at closed institutions and risk classes].

UNLABELLED: The residence and underlying diseases could be increase the severity and risk in the pneumonia in the elderly patient. BACKGROUND: To analyse demographics qualities and mortality in elderly inpatients with pneumonia, in relation with kind of residence, and to determine the risk classes distribution. METHOD: Were studied inpatients with 65 years old or more, with pneumonia in a period of 12 months, taking demographics values and underlying diseases, including each patient in a risk class (II to V). RESULTS: One hundred and three patients were studied (78.5 years mean age-SD 7.16), 67 males and 36 females, 80% includes in high risk classes, with 15.5% mortality. 17.5% were home nursing, older (82.7 years mean age-SD 5.72-) (p < 0.002), predominantly females and in high risk classes, and with lower length of hospital stay. CONCLUSIONS: The elderly patients with community-acquired pneumonia was high risk. Home nursing was older, more risk and lower length of hospital stay.

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[Lupus vulgaris. Treatment with 3 drugs].

We report two cases of lupus vulgaris one of them on scar of scrofuloderma. We review the treatment of the skin tuberculosis (TBC) and we observed the favorable development to the total regression, using rifampin-isoniazid-pyrizinamide in the first two months and rifampin-isoniazid the four months left to complete six months of global therapy. We discard the monotherapy as treatment for this disease.

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