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Biomedical subjects

J Chevallier

Publications and source records attributed to J Chevallier.

At least 73 records · Page 4Linked to original sources
PubMed1980

Sarcoplasmic reticulum vesicles from trembler mice: a comparison with material obtained from normal animals.

Sarcoplasmic reticulum (SR) vesicles were purified from trembler and normal mice. Comparison of their chemical composition showed that the only differences lay in their phospholipid content, the most obvious modification being the presence of lysophosphatidylcholine in preparations obtained from trembler animals. A significant increase of the Ca2+-stimulated ATPase activity promoted a drastic loss in the efficiency of the calcium pumping system of the membrane purified from trembler mice. It is suggested that the modification of the phospholipid content might explain this effect.

Adenosine Triphosphatases↗
PubMed1979

[Stoichiometry of calcium transport by sarcoplasmic reticulum: utilization of p-nitrophenylphosphate as an energy donor].

We have studied, under different conditions and through the hydrolysis of p-nitrophenylphosphate, the stoechiometry of the active transport of calcium by sarcoplasmic reticulum. According to a minimal kinetic model, it is possible to explain the variation of the coupling factor n(t) during the calcium accumulation in absence of precipitating agent. Under the described experimental conditions, at the beginning of the experiment, the coupling factor's value is slightly above 2.

Animals↗
PubMed1977

[Study of 728 cases of children with acute articular rheumatism, divided into 2 similar groups observed at an interval of 10 years].

A group of 364 children treated for acute rheumatic fever between 1955 and 1961 was compared with a similar group of 364 cases matched for age between 1965 and 1972, treated in the same fashion. In the second group an increase was found in the percentage of first attacks compared with relapses, indicating an improvement from prophylaxis. Cardiac involvement on admission, in first attacks, is equally common in both groups but more severe in the first group: in relapses, the severity of cardiac involvement increases with the number of previous attacks. The course of the carditis with corticosteroid treatment is the same in both groups. The reduced severity of the cardiac involvement in first attacks in the recent group suggests a role played by earlier diagnosis, antibiotic therapy previous to hospitalization, or variations in the epidemic nature of the disease.

Adolescent↗