PubMed Health⌕ Search

Biomedical subjects

J Close

Publications and source records attributed to J Close.

4 recordsLinked to original sources
PubMedDate not supplied

Dose-responsive characteristics of meperidine sedation in preschool children.

Using double-blind conditions, 60 uncooperative and fearful preschool children (24-66 months) received intramuscular injections of meperidine 0.25, 0.50, 1.00 mg/lb or placebo prior to restorative dental treatment. Behavior was assessed by the dentist and an independent observer during five specific treatment procedures. Behavioral ratings found meperidine to be an effective sedative, with 0.50 mg/lb and 1.00 mg/lb being significantly more effective than placebo (P less than 0.05, Kruskal-Wallis). Children receiving 1.0 mg/lb of meperidine had significantly more nausea and vomiting than patients receiving lower doses of the drug (P less than 0.05, Chisquare). Physiologic monitoring demonstrated that the highest dose of meperidine was associated with transient drops in arterial oxygen saturation. Meperidine sedation was found to be more effective for older children (37-66 months) and for children initially rated as being only moderately uncooperative and fearful.

Anxiety↗
PubMedDate not supplied

Efficacy of a prebrushing rinse for orthodontic patients.

The oral health benefits of a prebrushing rinse, when used in conjunction with an established twice-a-day brushing regimen, was investigated in a population of orthodontic patients. Twenty children (ages 11-18) who were undergoing orthodontic treatment that required brackets and labial wires were enrolled. This randomized, double-blind, cross-over clinical trial compared five weeks of twice-daily use of a commercial prebrushing rinse (Plax) to five weeks of a placebo rinse. Three investigators rated plaque accumulation (Simplified Oral Hygiene Index) and gingival health (modified O'Leary Index) prior to treatment and after each five week session. Because one child exited from the project and three children did not satisfactorily comply with the treatment protocol, sixteen children were used for the analysis. Although both treatment groups showed plaque and gingival improvement from pretreatment scores, no differences in plaque accumulation ratings and gingival health ratings were noted between the active and placebo rinse treatments.

Adolescent↗