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J Cordero

Publications and source records attributed to J Cordero.

11 recordsLinked to original sources
PubMed1992

Enterohemorrhagic Escherichia coli associated with hemolytic-uremic syndrome in Chilean children.

A clinicoepidemiological study was undertaken to determine if enterohemorrhagic Escherichia coli (EHEC) was associated with hemolytic-uremic syndrome (HUS) in children in Santiago, Valdivia, and Temuco, Chile. Prospective surveillance detected 20 hospitalized cases of HUS in children less than 4 years of age in these cities from March 1988 to March 1989. Each HUS patient was matched (by sex and age) with two control children (hospitalized elective-surgery patients). To detect EHEC, DNA from stool culture isolates of E. coli was detected by hybridization with biotin-labelled DNA probes specific for the EHEC virulence plasmid, Shiga-like toxin I (SLT-I) or SLT-II. Stool cultures from 6 of 20 cases (30%) and from 2 of 38 controls (5.3%) yielded EHEC (P = 0.0158). EHEC isolates from all HUS cases hybridized with the EHEC plasmid probe and with probes for SLT-I or -II (or both). The serogroups of the isolates included O157, O26, and O111. EHEC causes HUS in Chile, and the biotinylated gene probes are practical diagnostic tools for epidemiologic studies.

Bacterial Toxins↗
PubMed1990

[Fulminant hepatic failure in children].

We report the clinical characteristics and course of 38 children with fulminant liver failure. A viral etiology was demonstrated in 19 patients out of 25 with serologic screening (virus A in 17 patients, B in 2 patients). One patient had toxic liver damage from ingestion of a caustic substance. Mean age was 4 years and 6 months. Jaundice was present in all but 2 patients at admission. Encephalopathy developed at a mean of 13 days and 17 children were admitted with stage 3 or 4 coma. Evidence of severe liver failure was present in every patient. A lower prothrombin time and higher bilirrubin concentration were shown by non survivors. Hypoglycemia developed in 37% of patients, seizures in 37%, gastrointestinal bleeding in 45%, respiratory failure in 32% and severe infection in 32%. Overall mortality rate was 42% raising to 83% in patients with stage 3 coma at admission. Thus, although the etiology of fulminant liver failure differs in children as compared to adults, mortality rate and complications are similar.

Adolescent↗
PubMedDate not supplied

[Postangioplasty renal artery thrombosis treated intraluminally with thrombolysis. A case report].

The authors present the clinical case of a 31 year female with systemic vascular hypertension secondary to a 65 percent unilateral fibromuscular renal artery stenosis. The centellographic study demonstrated hypoperfusion on the right kidney and serious functional damage; the patient was subject to intraluminal renal angioplasty resulting in right renal arterial thrombosis, which was treated successfully with intra-arterial and intravenous streptokinase infusion. Following the thrombotic therapy, recanalization of the thrombosed artery and normal renal excretion of the contrast substance was observed.

Acute Disease↗
PubMedDate not supplied

[Hemolytic-uremic syndrome. Experience with 154 cases].

One hundred and fifty four patients with hemolytic uremic syndrome (HUS) were admitted from year 1968 throughout 1989 to a public children's hospital (n = 139) and to a private general clinic (n = 15) at Metropolitan Santiago, Chile. Their mean age at admission was 16 months, 64% of them were 6 to 18 month old. One third of patients were admitted at spring season. The prodromal phase lasted between 1 and 19 days. In 92% of cases there was antecedent diarrhea and 31% showed neurological involvement. Anuria was present in 44 patients (21%) lasting an average of 7 days; sixty one affected children (40%) became hypertensive. Sixty patients (39%) underwent peritoneal dialysis, remaining cases were given maintenance treatment for acute renal failure (ARF). No specific treatment was used except heparin in 5 children along the first years of these series. Ten patients (6%) died during the acute phase of their disease, but death occurred in only 2 of the 76 most recent cases, probably because of more accurate diagnosis and greater experience of the professional team in the management of ARF, even though very heterogeneous clinical presentations were observed along the whole observation period. Three patients developed chronic renal failure.

Acute Kidney Injury↗
PubMedDate not supplied

[Asphyxia by immersion].

Nineteen childhood near drowning cases admitted to a private general hospital from December 31, 1983 through out December 1987 at a mean age of 2 years 3 months are discussed. All patients had diagnosis when first found by relatives, 16 were apneic and only 11 received some kind of resuscitation which complied with accepted standards in 4 of them. Seven cases were admitted in stage A of Conn, two in stage B and ten in stage C. In six children in stage C intracranial pressure (ICP) monitoring was done and ICP was increased in two that died. Five patients developed clinical and radiological evidence of non cardiogenic pulmonary edema and 4 had hypotension sometime along the first 24 hours, requiring fluid therapy and inotropic drugs. Four patients died, all of them were in stage C when admitted. One child shows severe brain damage four years after discharge. The main complications after resuscitation were hemodynamic instability, pulmonary problems and hypoxic encephalopathy. High ICP was not important in the first hours and when it rose it did so 24 to 48 hours after admission. The need for an active role in prevention, improved resuscitation and transport, is stressed.

Asphyxia↗
PubMedDate not supplied

[Tetanus].

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Child↗