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Biomedical subjects

J Coulbois

Publications and source records attributed to J Coulbois.

17 recordsLinked to original sources
PubMed1986

Gastric form of alpha chain disease.

A case of alpha chain disease, involving the stomach only, is reported in an Algerian man suffering from epigastric pains. Upper digestive tract fibreoptic endoscopy showed two antral ulcers and an ulcerative gastritis pattern, which promptly disappeared with cimetidine treatment. Antral biopsies at a distance from the ulcers, but not of the ulcer crater itself, disclosed a dense infiltration of antral lamina propria by mature or sometimes atypical plasma cells. On transmural surgical antral biopsy, the infiltrate spread to the superficial part of the submucosa. No other localisation of the disease was found in spite of multiple biopsies obtained by endoscopy, with a peroral capsule and during staging laparotomy. The alpha chain disease protein was absent from serum and urine, but found in the gastric juice and in the cytoplasma of the cellular infiltrate (alpha 1 subclass). A complete clinical, endoscopic, histological and immunological remission was observed after a six months' course of oral tetracycline.

Adult↗
PubMed1978

[Malignant non-secreting cortico-adrenalomas. Four cases (author's transl)].

In three of these four cases of malignant tumour of the adrenal cortex, a prolonged fever and a major inflammatory syndrome were the presenting features. The precise diagnosis was made before surgery only once. In two cases, it was a surgical discovery (one patient operated upon with a false diagnosis and another with no precise diagnosis). In the last case, the malignant tumour of the cortex was discovered at autopsy. The chief characteristics of these tumours are reviewed: rare ; presenting with chest pain, a mass in the hypochondrium, metastases, or general symptoms, possibly high and prolonged fever. The prognosis is gloomy, the majority of patients dying the six months which follow the operation.

Adrenal Cortex Neoplasms↗
PubMed1977

[Intestinal hemorrhage due to blind loops. 3 cases and review of the literature].

The authors report 3 cases of intestinal bleeding either micro- or macroscopic induced by ulcers in blind loops. The blind loops developed in all 3 cases on side-to-side ileocolic anastomoses. In one of the patients, the ulcers were demonstrated by colonoscopy. The 3 cases reported are quite comparable to the 18 cases found in the world literature. These hemorrhages may become severe by their abundance or repetition, but a cure is easily obtained by resection of the intestinal blind loops and restoration of the continuity by end-to-end anastomosis.

Adult↗
PubMedDate not supplied

[Acute trichinosis. Several recent cases imported from Egypt (author's transl)].

Five cases of acute trichinosis imported from Egypt (four of them have been anatomically and serologically proved) have been recently observed at the Ambroise-Paré Hospital. The patients had been contaminated at Cairo. All of them but one presented atypical clinical picture. One of them was complicated with myocarditis, making the pronostic more severe. In 3 cases out of 5 immunological tests and blood eosinophilia were right one case remaining doubtful these reactions being negative. An anthelminthic, thiabenzadole, associated with corticotherapy, seems to have been efficient.

Acute Disease↗