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Biomedical subjects

J Csanádi

Publications and source records attributed to J Csanádi.

11 recordsLinked to original sources
PubMed1997

Gadolinium chloride-induced macrophage blockade prevents rejection of human insulinoma cell xenograft in rats.

The effect of gadolinium chloride (GdCl3)-induced Kupffer cell blockade on the survival of discordant insulinoma cell xenografts was investigated. Insulinoma cells isolated by means of collagenase from human insulinoma and subsequently cultured were transplanted through the portal vein into the liver of streptozotocin-induced diabetic, male, CFY inbred rats. In the control, streptozotocin-treated rats, the decrease in blood glucose level was only transitory, in contrast with the GdCl3-pretreated diabetic rats, which remained normoglycemic during the 2-week observation period. Histologically, in the liver and lung of rats pretreated with GdCl3, large areas of extensively proliferating insulinoma cells were seen, whereas no insulinoma cells were seen in either the liver or the lung of diabetic control rats, not treated with GdCl3. These studies suggest that the Kupffer cells play significant roles in the recognition of xenoantigens and the induction of xenograft rejection.

Animals↗
PubMed1993

[Lymphoid infiltrates in the lung].

The authors reviewed material of 10 year period (1980-1990) of the Department of Pulmonology, Albert Szent-Györgyi University of Medicine, Deszk, Hungary, and selected 14 patients from the files who considered to belong in one of the lymphoproliferative conditions (4 low grade and 4 high grade lymphomas of B-cell type, 1 angiocentric, 1 mediastinal lymphoblastic non-Hodgkin's lymphoma, 3 Hodgkin's lymphoma cases and 1 pleural pseudolymphoma). Every patient admitted with prominent pulmonary symptoms. The diagnoses were based on histology and immunohistochemistry of tissue samples and autopsy. One high grade B-cell and the angiocentric malignant lymphoma proved to be primary pulmonary process. No specific radiomorphological signs were found, which could be characteristic for the pulmonary lympho-reticular infiltrations and also to distinct the primary and secondary ones. The lung infiltrations in the most of the non-Hodgkin's lymphoma cases with low grade malignancy appeared imitating tuberculosis, while the high grade group and Hodgkin's lymphomas displayed confusion with any primary or multiple tumors.

Diagnosis, Differential↗
PubMed1992

[Barrett esophagus].

There are a lot of contradiction and uncertainty related to Barrett's esophagus. Authors review the literature about the incidence, the aetiology, the pathology of the ailment, the possibility of diagnosis and treatment. 25 Barrett's esophagus were observed in the course of controlling of patients after antireflux operations and investigations of patients suffering from gastroesophageal reflux disease. X-ray examination, endoscopy, biopsy, 24-hour pH monitoring of the distal esophagus and esophageal manometry were performed. Because of the possibility of malignant transformation Barrett's esophagus requires yearly endoscopic surveillance and biopsy at least. Antireflux procedure does not protect against the development of adenocarcinoma.

Barrett Esophagus↗
PubMed1991

[Cancer metastasis causing superior vena cava syndrome in the right heart].

In a 60-years-old woman, 1,5 year later of the diagnosis of the inoperable endocervical carcinoma vena cava superior syndrome developed. At autopsy mainly intracavital metastatic tumour mass was found in the right atrium of the heart. To the authors knowledge, intracavital heart metastatic tumor as cause of vena cava superior syndrome has not been described previously.

Carcinoma↗
PubMed1986

13C NMR study of actinoidins: carbohydrate moieties and their glycosidic linkages.

The configuration of the glycosidic linkages and the conformation of the carbohydrate moieties in the molecules of the glycopeptide-type antibiotics actinoidins A and B (1a, 1b) have been determined by means of two-dimensional 13C/1H correlation NMR technique and with the application of model compounds 2-4.

Carbohydrate Conformation↗