[Spinal involvement as first presentation of Hodgkin's disease].
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Biomedical subjects
Publications and source records attributed to J Cuesta Muñoz.
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An increase of the incidence of osteonecrosis in subjects infected with the HIV has been reported. It is unknown if osteonecrosis is an HIV infection consequence, or just the consequence of so many risk factors present among HIV infected subjects. We report five osteonecrosis cases found in our series of 534 HIV patients, and we review the related bibliography. All cases have some conventional risk factor different to the HIV or the antiviral treatment. We can't conclude antiviral treatments are not involved in osteonecrosis, but they have been the only risk factor in none of our patients.
We present a case of varicellous pneumonia in a 40-year-old patient without immunitary compromise, who quickly evolved to respiratory distress in the adult and required sustained ventilatory support. We review the literature, with special mention to the indications of the antivirical treatment with Aciclovir.
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Granulocytic and monocytic chemotaxis are studied by means of Boyden's modified method using as chemotactic agent human serum complement activated by Zymosan. The study has been made on healthy controls and a group of patients suffering from chronic renal failure treated with periodic haemodialysis. Observations were made before and after the dialysis session. In the patients with chronic renal failure is observed a decrease in leucocytic mobility of granulocytes and monocytes which give chemotactic granulocytic and monocytic indexes of 32.1 +/- 3.1 and 32.3 +/- 3.5 with relation to healthy controls with indexes of 46.7 +/- 8.4 and 37.0 +/- 4.3 and with significative differences between the measurements of p less than 0.001 and p less than 0.005 respectively. The parametres of polymorphonuclear and monocytic kinetics did not improve after the haemodialysis session. The possible mechanisms which produce such chemotactic leucocytic deficit in uraemics and the non-positive influence of the dialysis session on such deficit are hereby discussed.
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