OBJECTIVE: To review the treatment of invasive bladder cancer with ionizing radiation. METHODS: Patient selection criteria, prognostic factors, treatment of different tumor types with radiation using different strategies alone or in combination with chemotherapy are analyzed in the literature. RESULTS/CONCLUSIONS: The role of radiotherapy in the treatment of invasive carcinoma of the bladder is crucial: 1) preoperative radiotherapy in combination with radical surgery achieves results comparable with those of cystectomy in terms of survival and a higher local control rate; 2) used in combination with cisplatin post-TUR, irradiation is highly effective for local control of the tumor and bladder preservation, with complete remission rates ranging from 60-70%, which are higher than those of radical cystectomy; 3) in this latter therapeutic modality the effect of radiotherapy is dose-related and is influenced by factors such as tumor size, presence or absence of urinary obstruction, presence of multiple lesions on the bladder wall and extravesical spread. Over the last few years, a number of therapeutic procedures have been developed, which can improve the previously mentioned results when used appropriately. Among these are hyperfractionation, accelerated irradiation and concomitant radio and chemotherapy. Studies to determine tumor radiosensitivity (Fs2/a) and the use of gene therapy could enhance the tumor control rate in the future, although a system for the selection on patients for conservative or multilating treatment based on clinical, clinicopathological and scientific criteria will have to be developed. Finally, the use of special techniques, particularly brachytherapy and intraoperative irradiation, in combination with external radiotherapy has achieved excellent results (high local control and survival rates) in certain situations, basically in single/small-sized tumours.

Combined Modality Therapy↗

PubMedDate not supplied

Laparoscopic-assisted resection of a bleeding gastrointestinal stromal tumor.

The authors report a case of a 29-year-old male patient with a severe lower gastrointestinal hemorrhage in whom a successful laparoscopic diagnosis and resection (assisted) of an ileal gastrointestinal stromal tumor (GIST) was performed. Laparoscopy can be very useful in the diagnosis and treatment of selected cases of lower gastrointestinal bleeding.

Adult↗

PubMedDate not supplied

Laparoscopic diagnosis and treatment of an acute epiploic appendagitis with torsion and necrosis causing an acute abdomen.

Acute epiploic appendagitis is not as rare as previously thought; but, since the presenting signs and symptoms are not specific, preoperative diagnosis has been rarely made. At the present time, a laparoscopic exploration of the peritoneal cavity will establish the correct diagnosis, and the treatment can be provided during the same procedure. Herein, a case of a 63-year-old female patient with acute abdominal syndrome caused by a necrotic epiploic appendix that was successfully diagnosed and treated laparoscopically is described. A review of the literature is made, as well.

Abdomen, Acute↗

PubMedDate not supplied

Bowel obstruction in the postoperative period of laparoscopic inguinal hernia repair (TAPP): review of the literature.

A case is presented of a male patient that presented with intestinal obstruction in the early postoperative period of a transabdominal preperitoneal inguinal repair (TAPP) that was diagnosed and repaired successfully using laparoscopy. Whenever a total extraperitoneal procedure (TEP) cannot be performed, the peritoneal closure of the TAPP should be done water-tight using interrupted stitches of absorbable monofilament sutures.

Aged↗