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Biomedical subjects

J Czernicki

Publications and source records attributed to J Czernicki.

At least 19 recordsLinked to original sources
PubMed2000

Chronic exposure to 25-80-microT, 200-Hz magnetic field does not influence serum melatonin concentrations in patients with low back pain.

There is substantial evidence that magnetic field (MF) exposure influences melatonin secretion in animals. However, data on its influence on human melatonin levels are scarce, and seemingly contradictory. Because of its many beneficial effects, very low-frequency MF exposure is used in physiotherapy of some neurological diseases and overloading syndromes of the locomotor system. In previous studies, we observed a decrease in human serum melatonin nocturnal concentrations after exposure to MF (2.9 mT, 40 Hz), and we suggested that differences among various studies may depend on different characteristics of the applied MF. Therefore, in the present study, we examined whether or not MF of different parameters exerts the same effect. The study was performed in seven men (mean age: 36.7 +/- 3.8 years; range: 32-42) suffering from low back pain. Patients were exposed to a pulsating MF (induction: 25 80 microT; frequency: 200 Hz, modulated, automatically programmed; complex saw-like impulse shape; bipolar) generated by a Quatronic MRS 2000 apparatus ("magnetic bed") for 3 wk (5 days/wk, twice a day at 08:00 and 13:00 hr for 8 min each), applied to the whole body in patients laying in a horizontal position. The study was performed in spring. Diurnal serum melatonin profiles were estimated 1 day before exposure to MF (baseline), and 1 day and 1 month after the last exposure. No changes in melatonin concentrations were observed either after 1 day or after 1 month following the exposure in comparison to baseline.

Adult↗
PubMed1999

[Examination of the quality of life in post stroke patients].

The clinical assessment of patients after stroke is usually focused on the detection and determination of neurological deficits. However, the full picture of the patient after stroke should take into account also cognitive deficits, emotional and intellectual disturbances as well as limitations in performing one's social functions. Thus, assessing quality of life after stroke is an alternative to traditional methods of evaluation of the patient's condition. The study presents the attempts to define quality of life determined by the health status and to review questionnaires devised for the examination of post-stroke patients. Despite a considerable variety of methods used, reliable evaluation of all the areas of the patients life after stroke seems impossible using only one research tool. There is also an urgent need to develop an uniform system of evaluation, appropriate for Polish cultural standards.

Cerebrovascular Disorders↗
PubMed1999

[Evaluation of quality of life in patients after stroke].

The investigations concerning quality of life after stroke provide an alternative approach in comparison with traditional evaluation of the patient's condition focused only on neurological deficits. The full picture of the patient after stroke should take into account not only locomotor inefficiency, but also cognitive deficits, emotional disturbances and limitations in performing one's social functions. The study present attempts to define health related quality of life and reviews questionnaires devised for the examination of post-stroke patients. Despite a wide variety of methods used, the evaluation of all the areas of the patient's life after stroke seems impossible using only one research tool. There is also an urgent need to develop a uniform system of evaluation, appropriate for Polish cultural standards.

Adaptation, Psychological↗
PubMed1999

[Spasticity and physical methods for controlling it].

Spasticity is one of the greatest difficulties in patients with central nervous system injuries and diseases. Severe spasticity makes treatment, rehabilitation and care of patient very difficult and sometimes even impossible. It has been sought for many years for an objective method to evaluate the degree of spasticity, necessary to establish the results of treatment and rehabilitation. In this study we present subjective and objective methods of evaluating the spasticity in order to classify every patient to adequate therapeutic group. The authors present physical methods that not only contribute to control of spasticity together with pharmacotherapy and surgical treatment, but can be used alone. The big advantage of this therapy is a low invasiveness and the very few side effects.

Humans↗
PubMed1998

Chronic exposure to 2.9 mT, 40 Hz magnetic field reduces melatonin concentrations in humans.

Diurnal rhythm of serum melatonin concentrations was estimated in 12 men with low back pain syndrome before and after exposure to a very low-frequency magnetic field (2.9 mT, 40 Hz, square wave, bipolar). Patients were exposed to the magnetic field for 3 weeks (20 min per day, 5 days per week) either in the morning (at 10:00 hr) or in the late afternoon (at 18:00 hr). Significant depression in nocturnal melatonin rise was observed regardless of the time of exposure. This phenomenon was characteristic for all the subjects, although the percent of inhibition of melatonin secretion varied among the studied individuals.

Adult↗
PubMed1998

[The effect of pentoxifylline on treatment results and course of rehabilitation of patients after ischemic stroke].

The study has been taken up to compare the effect of treatment with pentoxifylline and typical treatment in early ischaemic stroke. The study included 107 patients aged 42-85, with the ischaemic stroke confirmed by CT scan, in early stage of stroke (within 24 hours after onset). Excluded from the study were patients with severe physical diseases. The patients were divided into two groups. Group I was treated typically, group II had been profited from a typical, appropriate therapy and pentoxifylline delivery during 30 days as well, with a daily dose of 1200 mg i.v. within the first 5 days followed by an oral dose of 800 mg subsequent days. Such a treatment has been continued until 12th month. The neurological state was assessed according to the European Stroke Scale (ESS) and Mathew Scale (MS), general fitness according to the Kamofsky Scale (KS) and Barthel Index (IB) at the admission, after 30 days and 12 months of the treatment. Quality of life assessment using by Oxford Handicap Scale and Frenchay Activities Index. After 30 days and 12 months of the treatment, no statistically significant differences between all study groups was found in: 1) mortality, 2) mean survival time, 3) neurological and functional state, 4) quality of life. According to the above results the beneficial influence of pentoxifylline treatment of ischaemic stroke was not confirmed.

Adult↗
PubMed1998

[Evaluation of the prognostic value of general motor activity for rehabilitation of patients after cerebral stroke].

Following cerebral stroke motor activity of the patient is dependent on the extensiveness of brain ischemia. Evaluation of this activity may be an exponent of brain ischemia extent. It can be used for the determination of predictability of patient survival and results of rehabilitation. Using Mathew and Barthel scales effectiveness of treatment and rehabilitation was evaluated four times during 12-month follow-up in patients of General Motor Activity Clinical Group II i III. The results obtained may be evidence of significant prognostic importance of evaluation of general motor activity of the organism in the initial period of treatment and rehabilitation only, i.e. within 3 months following cerebral stroke. However, it is no importance for evaluation of remote results (one year following cerebral stroke). The evaluation of general activity cannot be used to predict the dynamics of the improvement of neurological and functional status of patients undergoing rehabilitation following cerebral stroke.

Activities of Daily Living↗
PubMed1997

[A prognostic value of of stapedius reflex and accommodation coefficient in patients with Bell's palsy].

At 25 patients with Bell's palsy every 7 days stapedius reflex (SR), accommodation coefficient as well as improvement of mimical facial movements were examined. At 5 patients SR was noticed before treatment, at 13 after 14 days, at 4 after 21 and at 3 after 28 days since disease beginning. There was significant correlation between return SR and improvement of mimical facial movements, but there wasn't correlation between SR and accommodation coefficient.

Adolescent↗
PubMed1996

[Methods for evaluating treatment and rehabilitation progress in patients with stroke].

Based on the contemporary literature review, we have been introduced generally used neurological scales estimating the influence of new method of treatment on stroke progress. They are used to evaluate to treatment and rehabilitation progress. We also paid attention on the necessary elements, which every scale should contain and have been characterized generally used scales in neurological practice.

Cerebrovascular Disorders↗
PubMed1996

[The influence of laser radiation on blood flow in patients with ischemia of the lower limbs (based on the analysis of the hyperemia reactive test)].

The aim of this paper was to assess the influence of low power infra red laser radiation on blood flow in patients with atherosclerotic disease of the lower limbs. The investigations were based on the hyperemic reactive test and the ankle/brachial pressure index. Analysis of the hyperemic reactive test allows to evaluate microcirculation mechanisms. The results obtained indicate that treatment of low power laser radiation allows to improve microcirculation mechanisms and blood flow in the lower limbs.

Adult↗
PubMed1984

Red blood cell glutathione peroxidase activity in multiple sclerosis.

Glutathione peroxidase (GSH-Px) activity of red blood cells of 23 multiple sclerosis (MS) patients (10 men and 13 women, aged 22-64 years) was examined and compared to the enzyme activity of 26 healthy persons (15 men and 11 women, aged 19-50 years). It was found that the mean GSH-Px activity was significantly higher (P less than 0.001) in red blood cells of MS patients (39.1 +/- 8.1 IU/g Hb) as compared to the group of healthy persons (25.9 +/- 5.2 IU/g Hb). There was no difference according to sexes in both the MS patients and the control group. The results are discussed based on the hypothesis that organic peroxides play a role in the etiology of multiple sclerosis.

Adult↗
PubMed1983

Some T-cell functions in patients with viral myocarditis. The effect of polymorphonuclear leukocyte (PMNL) lysosome factors on T-suppressor cell activity in vitro.

The in vitro increase in mitogenic potency of lysosome factors derived from peripheral blood granulocytes of patients with chronic viral myocarditis was observed. These factors inhibited in vitro the Con A-induced suppressor cell activity measured in lymphocytes from healthy persons. The obtained results suggested that these factors may cause disturbances in suppressor cell function in the course of the foregoing disease.

Adult↗
PubMed1982

Some T-cell functions in patients with viral myocarditis. The effect of levamisole.

Some T-cell functions in vitro have been studied in 16 healthy persons, 8 patients with past myocarditis, without any circulatory after-effects and in 12 patients with chronic viral myocarditis. Decrease of T-suppressor cell activity and enhanced blastic transformation of lymphocytes induced with allogeneic heart antigens have been observed in patients suffering from myocarditis. In six patients with active inflammatory process of the heart muscle, application of levamisole brought about not only clinical and electrocardiographic improvement but also an increase of suppressor cells activity and diminished blastic transformation induced with the allogeneic heart antigens and a rise of the T-lymphocytes percentage.

Adult↗