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Biomedical subjects

J D Battaglia

Publications and source records attributed to J D Battaglia.

8 recordsLinked to original sources
PubMed1982

Neonatal surgery: changing patterns 1972-1980.

All cases of surgery in the neonatal period at The Children's Hospital during 1972 through 1980 were reviewed and classified; 1361 newborn infants came to surgery for 1696 procedures. During the years studied there was an almost fourfold increase in both procedures and patients. The most marked increase was in ligation of the ductus arteriosus in premature infants, which was not accompanied by an increase in surgery for necrotizing enterocolitis. Procedures for central alimentation rose markedly, usually for infants having had extensive abdominal surgery. Intestinal obstruction, omphalocele or gastroschisis, and cardiovascular anomalies increased, and shunting procedures for hydrocephalus rose faster than the incidence of myelomeningocele. Partial explanations for the changes in numbers and patterns may be found in an increasing local population, increase in the number and level of complexity of nursery beds, increasing neonatal survival, regionalization and transport patterns, and changes in medical management.

Colorado↗
PubMed1976

Respiratory failure associated with familial depression of ventilatory response to hypoxia and hypercapnia.

Respiratory failure has been associated with depressed ventilatory responses to hypoxia or hypercapnia or both. The possibility that familial factors are responsible for decreased chemosensitivity prompted this study of a child with unexplained respiratory failure and normal lung function. We found his ventilatory response to hypoxia and hypercapnia to be virtually absent. Studies of six healthy immediate family members (parents and siblings) showed that hypoxic response, as measured by an index of the relation between ventilation and hypoxia (index A), was consistently reduced: 45 +/- 8.7 S.E.M. (normal, 127 +/- 8.7) (P less than 0.005). Response to hypercapnia, measured as the slope of the ventilatory response to hypercapnia, was lower than normal, averaging 0.95 +/- 0.16 liters per minute per millimeter of mercury (normal, 1.76 +/- 0.13) (P less than 0.01). The patient's respiratory failure seemed related to deficient ventilatory responses to hypoxia and hypercapnia. It seems likely that this depressed hypoxic response is of familial origin.

Adolescent↗
PubMed1975

Management of acute epiglottitis by nasotracheal intubation.

In 40 cases of acute epiglottitis in children, intubation was the chosen method for the management of airway obstruction. Six patients were treated without the establishment of an artificial airway, and no tracheostomies were done. No patients who were admitted to the hospital died of airway obstruction, although one sustained irreversible brain damage before admission, and two died of overwhelming infectionmthe average duration of intubation was 2.days and the average hospital stay was 5.days. Two children developed subglottic granulation tissue that was removed successfully and did not recur. Nasotracheal intubation is an acceptable method of management of epiglottitis.

Acute Disease↗