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Biomedical subjects

J D Biggs

Publications and source records attributed to J D Biggs.

10 recordsLinked to original sources

The computer and your practice.

A sophisticated computer system allows a urology practice to run more efficiently and provides better control. All problems were not solved with the installation of such a system, and we developed a few problems that did not exist before computerization. However, this system has allowed our practice to grow with fewer additions to the office staff than would have been possible previously, and it has been our experience that the benefits far outweigh the problems.

Computers

A fatality involving methapyrilene.

Tissue concentrations of methapyrilene are given in a fatal case. There are no indications that methapyrilene had any synergistic or antagonistic effect with the patient's cardiopulmonary condition, although when taken in high overdosages the pharmacologic effects may be altered. This case was supported by other data in an attempt to elucidate as many contributing factors as possible in evaluating lethal levels.

Adult

Gases released from tissue and analyzed by infrared and gas chromatography/mass spectroscopy techniques.

Two techniques for analyzing contaminants released as gases from postmortem tissues were described and compared. One technique used gas chromatography/mass spectrometry (GC/MS); the other, infrared spectroscopy (IR). Brain, lung, liver, blood and urine specimens were obtained from suspected drug-overdose victims whose deaths were contributed to or caused by inhalation of unknown gases or vapors during the period immediately preceding death. Gases from the postmortem tissues and liquid samples were separately admitted into an evacuated IR gas cell, the IR spectra recorded, and gas samples then removed for GC/MS analysis. Nitrous oxide, glue, and paint solvent constituents were identified and measured. Only the brain and lung tissues contained measurable amounts of inhalants. Both IR and GC/MS methods were adequate for normal confirmatory analyses; the GC/MS system was judged superior for fast routine efforts normally hampered by incomplete sample history.

Brain Chemistry