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Biomedical subjects

J D Deck

Publications and source records attributed to J D Deck.

6 recordsLinked to original sources

The dynamic aortic root. Its role in aortic valve function.

By attaching appropriate measuring devices to the wall of an intact aortic root at the level of leaflet coaptation, we have measured a 16 per cent diameter change during each cardiac cycle. The dimensional changes observed can by themselves explain aortic valve function and obviate the postulation that the leaflets shorten and lengthen during each cardiac cycle. The tissue composition of the aortic root and leaflets is more compatible with this theory than with other postulations. Such a dynamic aortic root may explain the longevity of the actual aortic leaflets, in that leaflet fatigue stress is minimized by changes in aortic root dimension.

Animals

The effect of denervation on bony overgrowth after below knee amputation in rats.

Bony overgrowth of amputated limbs of children is an infrequent but difficult problem. This article presents the hypothesis that the bony overgrowth is under nerve control and may represent an abortive form of partial limb regeneration. Tested in young rats, denervation produces a significant reduction in the mass and length of the bony overgrowth and a reduced rate of periosteal cell mitosis.

Amputation, Surgical