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Biomedical subjects

J D Jackson

Publications and source records attributed to J D Jackson.

87 records · Page 5Linked to original sources
PubMed1984

CO2 laser conization versus conventional conization: a clinico-pathologic appraisal.

Two groups of patients recently underwent either laser or conventional conization at the University Women's Hospital in Bern, Switzerland. Of the total 49 patients treated, 25 underwent laser conization and 24 underwent conventional conization. All patients admitted to the study had cytologic, colposcopic, and/or histologic evidence for cervical intraepithelial neoplasia or chronic cervicitis resistant to conservative therapy. In the conventionally treated group, conization was performed with surgical scalpel, and hemostasis was achieved by Sturmdorff, Bonney, or Kraus sutures. In the laser-treated group, conization was performed by using the combination method of Dorsey and Grundsel. Blood loss was minimal in the laser-coned patients, compared to 119 ml blood loss in the conventionally coned patients. Hospitalization for the laser-treated group was 5.2 days in contrast to 7.0 days for the conventionally treated group. Postoperative bleeding and discharge were also considerably smaller or did not occur in the laser-treated group as compared to the conventionally treated group. With postoperative and long-term follow-up now under way, initial results indicate that laser conization, in comparison to conventional conization, also provides greater visibility of the squamocolumnar junction and a reduced incidence of cervical strictures. The results of this study suggest that the CO2 laser beam, properly and cautiously applied, is an efficacious surgical modality for the treatment of cervical preneoplastic disease.

Cervix Uteri↗
PubMed1984

Surgical management of endometriosis with the carbon dioxide laser.

This study was designed to evaluate the efficacy of reconstructive microsurgery with the carbon dioxide laser for the treatment of infertile women suffering from endometriosis. One hundred and eight women evaluated for infertility and endometriosis underwent reconstructive microsurgery with the carbon dioxide laser. All cases were classified in accordance with the American Fertility Society's classification. Postoperatively, conception rates for the mild-to-moderate and the severe-to-extensive groups were estimated by life table methods for analysis. Estimates of the cumulative pregnancy rate were 55% for the mild-to-moderate group and 88% for the severe-to-extensive group. The abortion rate was 17% and the ectopic pregnancy rate was 3%.

Actuarial Analysis↗
PubMed1984

Application of the CO2 laser to infertility surgery.

In addition to use of the CO2 laser in gynecologic surgery for the treatment of pelvic, vaginal and vulvar neoplasms, it has been more recently applied to the treatment of infertility. The advantages afforded by the laser over conventional techniques are discussed. The authors' clinical experience in the surgical treatment of infertility, with emphasis on endometriosis and microtubal surgery, are described, and use of the new electro-pulsed laser in infertility surgery is evaluated.

Carbon Dioxide↗
PubMed1983

PaperChase. Self-service bibliographic retrieval.

During the past three years, from terminals within Beth Israel Hospital, Boston, 3,654 persons used a computer program called PaperChase to search the medical literature. While performing 39,022 searches, these persons had 1,976,421 references displayed and selected 449,690 of them for printing. Throughout this period, the program underwent continual modification. Each year the number of searches increased--from 10,678 to 11,541 to 16,803. Each year the percentage of new users who were unsuccessful decreased--from 16 to 13 to 11. By the end of the third year, 549 people had completed 20 or more searches. PaperChase enables people to search the medical literature themselves, and thus provides a new experience in computerized bibliographic retrieval. When made available without charge in a teaching hospital, PaperChase is widely used.

Boston↗
PubMed1982

An investigation of prescribed and nonprescribed medicine use behavior within the household context.

The goal of this study was to study empirically individual and household characteristics and their relation to individual medicine use behavior. The study accounted for 40% of the variance in prescribed medicine use and 20% of the variance in nonprescribed medicine use behavior for 545 AFDC households in Northern Mississippi. Perceived morbidity was the primary mediator of medicine use and 57% of the explained variance in nonprescribed medicine use. Age was a significant contributor to the variance explained in prescribed medicine use behavior. The use of nonprescribed medicines by other members of the household also significantly enhanced individual nonprescribed medicine use. Although many of the other individual and household variables were significant predictors of medicine use behavior they contributed little to the total explained variance. Research concerning medicine use in the context of the household is in the initial stage of theory development.

Age Factors↗
PubMed1981

Computerized radiologic reporting with voice data-entry.

The accurate, voice entry of radiologic reports into a computer takes significantly longer than entry by keyboard. Careful speech and considerable patience are required to avoid an unacceptably high error-rate. With improvements in the future, this technology may compete with the conventional technology.

Computers↗
PubMed1981

Citrus artifact interference in aflatoxin M1 determination in milk.

Dried citrus waste was fed to dairy cows, their milk was extracted, and aflatoxin M1 was quantitated by using both high pressure liquid chromatography (HPLC) and thin layer chromatography (TLC). Results indicate that a compound from the citrus waste, which is excreted into the milk, interferes with the HPLC determination of aflatoxin M1 in milk and causes a false positive test. This interference can be overcome by using TLC with proper selection of developing solvents.

Aflatoxin M1↗
PubMed1979

Advances in radiologic reporting with Computerized Language Information Processing (CLIP).

Computerized Language Information Processing (CLIP) is a system of radiologic reporting in which the user interacts with a computer keyboard and cathode-ray tube terminal to generate coded reports. The hierarchical medical classification on which the code is based permits rapid on-line compilation of reports of any degree of complexity. The system provides organized sets of pre-assembled statements that are rapidly accessed and modified for each examination. Although the reports are printed in English, they are held in the computer as a succinct code that is eminently suited for permanent storage and rapid retrieval.

Classification↗
PubMedDate not supplied

Purification of monoclonal antibodies using high performance liquid chromatography (HPLC).

Recent increases in the ability to detect low levels of immunofluorescence have shown the need for highly purified primary immunoreagents. There are now reports of purification of monoclonal antibodies using HPLC with reverse phase columns. In this study we have utilized standard size exclusion HPLC to purify both biotinylated and non-biotinylated monoclonal antibodies from hybridoma culture supernatants. Results indicated that both biotinylated and non-biotinylated monoclonal antibodies retained their antigen binding capacity after purification, and were not different in this capacity from commercially available, affinity purified reagents. These findings indicate that size exclusion HPLC may be used in the purification of biologically active monoclonal antibodies, and suggest that this technique may be used in the large scale production of antibodies and their fragments, in antibody purification from ascites fluid, and in antisera quality control.

Animals↗
PubMedDate not supplied

Age differences in summarizing descriptive and procedural texts.

This study compared young and older adults' summaries of expository texts under the hypothesis that older adults would be more experienced, hence more accurate, at summarizing texts. Two types of expository texts were used: procedural and descriptive texts. The texts were read by a panel of judges who wrote summaries of each text and identified the central ideas of each text; the judges' summaries were used to prepare lists of the central ideas of each text and to write standard summaries of each text. The participants read four texts, two orally and two silently, and then wrote summaries, which were limited to 50 words. Words-per-minute reading times were collected and the summaries were scored on two measures of content, how many ideas were reproduced from the original texts and the proportion of central ideas that were reproduced, and two measures of length, the number of sentences and the number of words. Although the older adults read more slowly than the young adults, the older adults reproduced more total and central ideas than the young ideas.

Adult↗