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Biomedical subjects

J D Key

Publications and source records attributed to J D Key.

At least 19 recordsLinked to original sources
PubMed1997

Illness and injuries at summer camp.

Children at summer camp are at risk of injury and illness. The American Academy of Pediatrics and the American Camping Association have specific guidelines for the medical care of children in summer residential camps. This report describes the types of illnesses and injuries seen in 730 children attending camp for 2 weeks, use of the infirmary, and difference in the onset of infectious diseases compared with injuries during the camp session. During the month studied, there were 921 infirmary visits. The most common diagnoses were injuries and infectious disease. Girls and boys were equally likely to be seen in the infirmary and had the same distribution of diagnoses. Infectious disease (gastroenteritis) had a later mean day of onset during the camp session than did injuries and was increasing in frequency at the end of each session. Potential common camp medical problems (sunburn, otitis externa) were prevented by simple medical preventive care.

Adolescent↗
PubMed1995

Adolescent medicine in pediatric practice: a survey of practice and training.

This study was designed to assess the relation between training in adolescent medicine, during and after residency, and self-reported practice of adolescent medicine. This is a cross-sectional study. A questionnaire was mailed to all members of the South Carolina Chapter of the American Academy of Pediatrics. After 2 mailings, 198 (83%) questionnaires were returned. Adolescent medicine training in residency was associated with more adolescent patients enrolled in a practice (P < 0.01) and more adolescent patient visits (P < 0.01) but not with an increase in perceived competence in the practice of adolescent medicine. Adolescent medicine continuing medical education was associated with seeing more adolescent patients and with increased competence in many areas, including contraceptives, suicide, and school problems (P < 0.05). training in adolescent medicine during and after residency is associated with treating more adolescent patients. Continuing medical education also is associated with increased perceived competence in areas related to adolescents.

Adolescent Medicine↗
PubMed1994

Calcium needs of adolescents.

Adolescents grow at the greatest rate of any age group after infancy and accumulate 37% of their total bone mass during this growth spurt. Because maximum bone mass is acquired during adolescence, the calcium deposited during adolescence determines the risk of osteoporosis and fracture in adulthood. Bone mass is dependent on calcium intake, growth and pubertal development, exercise, and genetic and racial factors. Unfortunately, during this time of tremendous calcium need, most adolescents eat a diet that is very deficient in calcium. Girls are twice as likely to be deficient as boys (85% vs 43%). Other factors contributing to poor bone mineralization include adolescent pregnancy, anorexia nervosa, excessive exercise, and various chronic medical conditions. To avoid osteoporosis in later life, adequate dietary calcium intake should be recommended and calcium supplementation considered in all adolescent patients.

Adolescent↗
PubMed1994

Bicycle-related head injuries in South Carolina children: what can we do to prevent them?

This review article demonstrates the clear need for helmet usage in children everywhere. The lives that could be changed and the money that could be saved from needless injury and death is substantial. As physicians and community leaders, we must all do our part to ensure the safety of children. This must be done by joining or initiating a local community campaign. Physicians need to become part of this preventive effort, both with their patients and by example. Hopefully, by following the suggestions of other programs already implemented throughout the United States and working together with the community, we can substantially decrease the number of needles bicycle injuries suffered by South Carolina's children.

Adolescent↗
PubMed1992

Pulmonary embolus in an adolescent on oral contraceptives.

Deep venous thrombosis with pulmonary embolus is a rare complication of oral contraceptives, which generally occurs in adult women and becomes more common with increasing age. These complications are believed to be less common with low dose oral contraceptives than with the higher dose forms. This is a case report of a deep venous thrombosis presenting with a life-threatening pulmonary embolus in an adolescent on low dose triphasic oral contraceptives.

Adolescent↗
PubMed1992

Humanism and values in the medical short stories of Arthur Conan Doyle.

In 1894 Arthur Conan Doyle published 15 medical short stories under the title of Round the Red Lamp, a red lamp being the symbol for a physician's office in Victorian England. These 19th-century vignettes do not indulge in scientific descriptions of diseases, their processes, or their treatment. Instead, they are based upon the effects of illness on the lives, sentiments, and emotions of the afflicted, their families, and their physicians. The stories are suffused with romance and humor. Conan Doyle's medical fiction of almost 100 years ago constitutes a superbly written and engaging collection that ranges from the comic to the pathetic. They contain universal themes that are especially appropriate today when humanistic elements are being usurped by rampant technology in both medical education and medical practice. These tales can make a significant contribution in related seminars for both students and practitioners.

England↗
PubMed1991

Arthur Conan Doyle, Joseph Bell, and Sherlock Holmes. A neurologic connection.

Neurologists, like physicians in several other medical specialties, can lay claim to Sherlock Holmes as one of their own. This assertion is validated by the number of neurologic conditions, such as seizures, stroke, syncope, encephalopathies, and head trauma, that are mentioned in the stories and novels. In addition, the article reviews the powers of observation and the deductive approach utilized by Conan Doyle and Joseph Bell, the models for Sherlock Holmes, and how these skills can be applied to medical problems.

Drama↗
PubMed1990

Osler's brain and related mental matters.

Interest in the relationship between the morphology of the brain and mental and behavioral characteristics was evident in the 18th century; it flourished in the 19th century and waned during this century. This concern has been expressed in several activities. The weight and cortical area and gyral patterns of brains have been measured in detail in prominent and highly intelligent individuals, such as William Osler, Thomas Browne, and Albert Einstein, as well as in "average" individuals and in criminals. Phrenology is based on the assumption that various modalities of behavior are localized to specific morphologic areas of the brain. Little credence is now given to the mental, behavioral, and psychosocial significance of brain weight and gyral patterns. Practices based on such concepts are now considered by most to be a manifestation of quackery, though phrenology is still believed in by some.

Brain↗
PubMed1988

Citation classics: most-cited articles from Archives of PM&R.

The purpose of this brief study was to identify the most-cited articles in the Archives of Physical Medicine and Rehabilitation based on citation counts using the 1955 through 1986 Science Citation Index (SCI) of the Institute of Scientific Information (ISI). Bibliographic coupling is one measure of a landmark or classic article. The study resulted in identifying 14 citation classics for this journal.

Periodicals as Topic↗
PubMed1987

Glutathione metabolism in normal and cystinotic fibroblasts.

Intracellular concentrations of glutathione and activities of the enzymes gamma-glutamylcysteine synthetase, glutathione synthetase, and gamma-glutamyl transpeptidase were measured in confluent cultured human fibroblasts cell lines from 14 normal cell lines and four cystinotic cell lines. gamma-Glutamyl transpeptidase had a wide range of variability while the glutathione synthetic enzymes, gamma-glutamylcysteine synthetase and glutathione synthetase, had narrower variations and also exhibited no apparent relationship to glutathione content. No differences in the activities of these enzymes were found between normal and cystinotic cells in confluent cell cultures. The activities of the above enzymes and the cell number and content of glutathione, cystine, DNA, and total protein in two normal and two cystinotic fibroblast cell lines were measured during growth. The following growth-dependency patterns were observed: (1) gamma-glutamylcysteine synthetase activity increased markedly in lag and early log phases in both normal and cystinotic cells and decreased rapidly to low confluent levels thereafter. (2) gamma-Glutamyl transpeptidase showed the same wide range of activity noted at confluency but activities decreased in the log phase of growth, a pattern also seen in cystinotic cells. (3) Glutathione synthetase activity remained relatively constant during growth of normal cells but exhibited a peak of activity during lag and early growth of cystinotic cells. (4) Comparative glutathione levels of normal and cystinotic cells were not significantly different and exhibited similar fluctuations with time. (5) The cystine content of normal and cystinotic cells unexpectedly rose to high levels in the lag phase, then decreased to 0.1 nmol 1/2 cystine/mg protein in normal cells and to 0.3 to 1.2 nmol 1/2 cystine/mg protein in cystinotic cells during the log phase. As confluency was approached, normal cell cystine remained at low levels while cystinotic cell cystine rose to characteristically high levels of 50- to 100-fold greater than normal cells at late confluency. These studies extend our understanding of the regulation of glutathione and cystine content in cultured fibroblasts and suggest that glutathione content is closely controlled throughout the cell cycle in the face of varying activities of its anabolic and catabolic enzymes.

Cell Division↗