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Biomedical subjects

J D Morin

Publications and source records attributed to J D Morin.

53 records · Page 3Linked to original sources
PubMed1971

Rubeosis iridis.

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Aortic Arch Syndromes↗
PubMedDate not supplied

Early local steroid therapy of infantile eyelid hemangiomas (local steroid therapy of lid hemangiomas).

Two cases of upper eyelid capillary hemangiomas were successfully treated by local injection of steroids. Both cases required two injections, performed between 11 and 20 weeks of age. No untoward side effects occurred. This treatment would appear to be valuable in preventing the development of ophthalmic sequelae commonly associated with benign observation.

Dexamethasone↗
PubMedDate not supplied

Surgery of infantile esotropia: a critical evaluation of marginal myotomy of the medial recti as a primary and secondary procedure.

Seventeen cases of marginal myotomy were compared to 88 conventional procedures in treatment of infantile esotropia. Successful alignment (within 10 prism diopters of orthophoria) was less frequently attained in the marginal myotomy group than in the conventional group, both after one surgery (18% versus 40%, respectively) and finally (24% versus 65%, respectively). Motor and sensory findings were similar in each group, although fusion and stereopsis were less frequent with marginal myotomy. Even though nearly all patients receiving marginal myotomy were successfully aligned immediately following surgery, a gradual return of esotropia was noted in 12 of 17 patients. The significantly inferior ability of marginal myotomy to produce stable successful alignment in infantile esotropia should incontrovertibly lead to the abandonment of marginal myotomy in favor of the vastly superior recession and/or resection procedures. Twenty-one cases of marginal myotomies of the medial recti performed as secondary procedures were also analyzed. The group receiving myotomy with resection had much better results (4 of 5 successfully aligned, average exo-shift 27.6 P.D.) than the myotomy only group (2 of 17 successfully aligned, average exo-shift 6.6 P.D.). Three of 17 were actually made more esotropic by the myotomy procedure alone. It is concluded that isolated myotomy is an ineffective reoperative procedure, and that by combining myotomy with resection, a fair rate of successful alignment may be achieved.

Age Factors↗
PubMedDate not supplied

Bilateral acquired inflammatory Brown's syndrome.

An 11-year-old boy presented with fever, skin rash, joint pains and vertical diplopia, and was found to have a right Brown's syndrome and systemic onset Juvenile Rheumatoid Arthritis (JRA). Later in the course of his illness, he developed a left Brown's syndrome. Acquired Brown's syndrome may occur as a complication of JRA during exacerbations of the systemic inflammatory disease.

Arthritis, Juvenile↗
PubMedDate not supplied

Horner's syndrome in children.

Ten cases of Horner's syndrome with pharmacologic testing and computed tomography scans are described in patients up to age 8 years. The patients also were assessed for iris color and facial sweating. Classical preganglionic Horner's syndrome associated with brachial plexus birth injury was not identified in any case. Two patients who presented with ptosis had neuroblastoma. Two other children had undergone corrective cardiothoracic surgery. Two patients had major congenital abnormalities. In four patients, no cause of Horner's syndrome was determined.

Adrenergic Fibers↗
PubMedDate not supplied

Pars plicata lensectomy/vitrectomy for developmental cataract extraction: surgical results.

Fifty-two cases of developmental cataracts extracted using the pars plicata lensectomy/vitrectomy technique were reviewed. Eyes with additional ocular anomaly other than microphthalmos were not included. No early complications were detected in a postoperative period ranging from 1.5 to 7 years with a median of 4 years, and late complications were limited to secondary membranes occurring in small eyes. Since secondary membranes occurred only in eyes in which the axial length was less than or equal to 17.4 mm and the corneal diameter was less than or equal to 9.5 mm, we suggest that eyes that are small by the absolute dimensions cited here are at greater risk of developing secondary membranes postoperatively. Small eyes by absolute dimensions should be distinguished from microphthalmic eyes, since the relative term microphthalmic is less predictive of risk of complication than are absolute dimensions. Linear Snellen acuity in 15 patients capable of response ranged as follows: 20/20-20/80 with a median of 20/40 in eyes with partial bilateral cataracts; 20/25-20/80 with a median of 20/50 in eyes with complete bilateral cataracts; 20/30-20/400 with a median of 20/200 in eyes with unilateral partial cataracts; and 20/60-CF with a median of 20/400 in eyes with complete unilateral cataracts. Mean patient ages at surgery were 3 months for those with bilateral complete cataracts, 5 months for those with unilateral complete cataracts, 18 months for those with bilateral partial cataracts, and 25 months for those with unilateral partial cataracts. The earliest possible removal of visually significant opacities must be combined with aggressive postoperative visual rehabilitation to obtain the best possible visual outcome.

Cataract Extraction↗
PubMedDate not supplied

The ocular manifestations of the Sturge-Weber syndrome.

Sturge-Weber syndrome (SWS) is a rare neuro-oculocutaneous disorder. The ocular component manifests as glaucoma and vascular malformations of the conjunctiva, episclera, choroid, and retina. The authors reviewed the records of and recalled for examination 51 consecutive patients with a diagnosis of SWS seen at The Hospital for Sick Children, Toronto, Ontario, Canada, from 1980 to 1991. Of the 51 patients, 36 (71%) had glaucoma, 26 experienced onset before 24 months of age and the remainder after 66 months of age, 35 (69%) had conjunctival or episcleral hemangiomas, and 28 (55%) had choroidal hemangiomas, which were bilateral in 12 patients. Other ocular manifestations (retinal vascular tortuosity, iris heterochromia, retinal detachment, and strabismus) also occurred. Thirty-four of 51 (67%) glaucomatous eyes had a final visual acuity of 20/40 or better, or central, steady, and maintained fixation in each eye.

Child↗
PubMedDate not supplied

Bovine surfactant therapy and retinopathy of prematurity.

We reviewed the results of three randomized clinical trials of prophylactic bovine surfactant therapy on babies under 30 weeks gestational age to assess the effects of this treatment on the frequency and severity of retinopathy of prematurity (ROP). Of the 119 babies who received surfactant treatment, 54 (45.4%) had ROP compared to 33 (47.1%) of the 70 babies in the control group. Stage 2 ROP or greater was noted in 10 (8.4%) babies in the treatment group and in 10 (14.3%) of the untreated group. Prophylactic bovine surfactant replacement therapy does not have a significant effect on the frequency of ROP in preterm babies. The severity of ROP also appears to be unaffected by surfactant.

Animals↗