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Biomedical subjects

J D Robison

Publications and source records attributed to J D Robison.

7 recordsLinked to original sources
PubMed1992

Intrarater reliability of manual muscle test (Medical Research Council scale) grades in Duchenne's muscular dystrophy.

The purpose of this study was to document the intrarater reliability of manual muscle test (MMT) grades in assessing muscle strength in patients with Duchenne's muscular dystrophy (DMD). Subjects were 102 boys, aged 5 to 15 years, who were participating in a double-blind, multicenter trial to document the effects of prednisone on muscle strength in patients with DMD. Four physical therapists participated in the study. Two identical (duplicate) evaluations were performed within 5 days of each other by the same examiner initially and after 6 and 12 months of treatment. A total of 18 muscle groups were tested on each patient, 16 of them bilaterally, using a modification of the Medical Research Council scale. Reliability of muscle strength grades obtained for individual muscle groups and of individual muscle strength grades was analyzed using Cohen's weighted Kappa. The reliability of grades for individual muscle groups ranged from .65 to .93, with the proximal muscles having the higher reliability values. The reliability of individual muscle strength grades ranged from .80 to .99, with those in the gravity-eliminated range scoring the highest. We conclude the MMT grades are reliable for assessing muscle strength in boys with DMD when consecutive evaluations are performed by the same physical therapist.

Adolescent↗
PubMed1989

Effects of passive immunity on subsequent production in dairy heifers.

Dairy Herd Improvement data from a large, commercial dairy farm were used to evaluate the relationships of first lactation milk and fat yield and age at first calving on passively acquired immunity in Holstein heifers. Total serum Ig concentration was measured 24 to 48 h postpartum (mean = 25.5 mg/ml, SD = 19.2) on calves allowed to suckle their dams freely through 24 h postpartum. No additional colostrum was supplied and no attempt was made to ensure adequate colostrum intake. Calves were raised in Tucson, AZ until 6 mo of age, then transferred to Idaho to complete the growing phase and to be bred. Heifers were returned to Tucson during their 7th or 8th mo of gestation. Serum Ig concentration, measured shortly after birth, was an important source of variation for mature equivalent milk (b = 8.5 kg/Ig unit) and mature equivalent fat (b = .24 kg/Ig unit) production in the first lactation but did not affect age at first calving. It is impossible to ascertain from these data whether Ig concentration at birth was directly or indirectly related to production; regardless, supplying an adequate amount and concentration of colostrum at the appropriate time to dairy heifers may enhance their future productivity.

Animals↗
PubMed1988

Effects of passive immunity on growth and survival in the dairy heifer.

Effects of 24 to 48 h serum Ig concentration on growth and survival of 1000 Holstein heifer calves were evaluated. Average serum Ig for all calves was 25.71 (SD = 19.06) mg/ml with a range of .05 to 108.27. Serum Ig concentrations were below 12 mg/ml in 28% of the heifers. Both season and age of dam contributed significantly to the variation in 24 to 48 h concentrations of serum Ig. Concentration of serum Ig at 24 to 48 h was a significant source of variation affecting average daily gain through the first 180 d of life. Seasonal factors also were significant in influencing rate of gain from birth to 180 d. Age of dam was a significant source of variation in calf weight gains but only for the first 35 d. Mortality was 6.78% for heifers with less than 12 mg/ml serum Ig at 24 to 48 h as compared with 3.33% mortality for calves with greater than 12 mg/ml concentration.

Animals↗
PubMed1985

Reliability of goniometric measurements in patients with Duchenne muscular dystrophy.

Previous studies of reliability of goniometric measurements have produced varied findings suggesting the need to document further the reliability of measuring range of motion in different patient groups. The purpose of this study was to determine the intratester and intertester reliability of goniometric measurements of seven common upper and lower extremity joint limitations in children with Duchenne muscular dystrophy. Five physical therapists participated in the study. The procedure and order of measurements were standardized. Results showed that intratester reliability for all measurements was high (ICC = .81 to .94), but intertester reliability showed a wide variation (ICC = .25 to .91). The results of this study indicate the need to use the same examiner for long-term follow-up and for assessing results of specific treatment interventions.

Adolescent↗
PubMed1984

Clinical trials in Duchenne dystrophy. Standardization and reliability of evaluation procedures.

A multiclinic, collaborative study has been designed to assess the natural progression and efficacy of treatment of Duchenne muscular dystrophy. This article describes the protocol for the evaluation technique and the method used to establish within (intraobserver) and between (interobserver) reliability of the protocol evaluation procedures. Standardized patient evaluations were used, and consistency of evaluation was monitored by a computer. The reliability of the measures was analyzed 1) within observers by comparing the results of each of the first three tests done by each evaluator for all patients and 2) between observers by comparing, at multicenter group meetings, the results of each of the four evaluators' tests of the same patient. We have demonstrated reliability for an evaluation method that will provide an objective foundation on which to claim a drug or therapeutic procedure does or does not have an effect in treating Duchenne muscular dystrophy.

Adolescent↗
PubMedDate not supplied

Prolongation of ambulation in children with Duchenne muscular dystrophy by subcutaneous lower limb tenotomy.

To assess the effect of subcutaneous (s.c.) lower limb tenotomies on the ambulatory ability of patients with Duchenne muscular dystrophy (DMD), 54 patients were followed. Twenty-nine patients underwent hip, knee, and ankle tenotomies at a mean age of 10 2/12 years and were followed postoperatively for an average of 3 9/12 years. These children continued ambulation in long-leg braces to a mean age of 12 8/12 years and stood to an average of 13 5/12 years. Contracture correction was 49% at the hip, 58% at the knee, and 100% at the ankle. A separate group of 25 children to whom operation was offered but declined, was followed: these children ceased ambulating at a mean age of 10 years and ceased standing at a mean age of 10 2/12 years. Thus, we propose that s.c. tenotomy is effective in allowing braced ambulation well beyond what the natural history would allow.

Achilles Tendon↗