Biomedical subjects
Publications and source records attributed to J D Toft.
A 40-year-old male chimpanzee had multiple intestinal polyps associated with immature male oxyurid parasites. The gross and histologic characteristics of these lesions were identical to those produced by Nochtia nochti in the stomach and esophagus of Old World primates. It was theorized that the lesions resulted from hypersensitivity to oxyurid infection in an aberrant host.
A female juvenile rhesus monkey experienced a 3-wk period of vague lameness and limb disuse, followed by a severe attack of acute polyarthritis resulting in marked radiographic changes. The acute condition lasted about 3 wk and was followed by a chronic but active condition lasting another 13 mo until the animal was killed. Although a causative organism was not isolated, serologic and clinical laboratory data and histopathologic results were presented which suggest a diagnosis of mycoplasma polyarthritis.
A 25-year-old female chimpanzee with disseminated tuberculosis also had two uterine tumors. One a typical leiomyoma and the other, which occluded the uterine lumen, was composed of cells resembling normal endometrial stroma in its proliferative phase. It was diagnosed as an endometrial stromal tumor and was similar to that which occurs in the human female. This is the first report of this lesion in a nonhuman primate.
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