PubMed Health⌕ Search

Biomedical subjects

J D Whiting

Publications and source records attributed to J D Whiting.

6 recordsLinked to original sources

The confirmation of 9-carboxy-THC in urine by gas chromatography/mass spectrometry.

A mass spectral method for the identification of the urine metabolite of THC, 11-nor-delta-9-tetrahydrocannabinol-9-carboxylic acid, has been developed. The metabolite is extracted from the urine, derivatized to the methyl ester, methyl ether, and analyzed on a gas chromatograph/mass spectrometer. Identification of the metabolite is based on the retention time of the derivatized compound and its electron impact (EI) or chemical ionization (CI) mass spectrum. The EI spectrum shows three characteristic ions at masses 313, 357, and 372 (the molecular ion). When methane is used as the reactant gas, the CI spectrum shows an ion at 341 and an M + 1 ion at mass 373.

Dronabinol↗

EMT knowledge of ambulance traffic laws.

OBJECTIVE: The safe operation of ambulances using warning lights and siren requires both the public and emergency medical technician (EMT) drivers to understand and obey relevant traffic laws. However, EMTs may be unfamiliar with these laws. The purpose of this study was to evaluate EMTs' knowledge of traffic laws related to the operation of ambulances with warning lights and sirens. METHODS: North Carolina EMTs participating in a statewide EMS conference October 6-8, 1995, completed a five-question survey. Knowledge of ambulance speed limits, yielding at intersections, yielding in roadways, and following distances was assessed using a multiple-choice format. Demographic data pertaining to EMT age, years of experience, paid vs volunteer status, driver's education courses, and past accident involvement were also obtained. Proportions were compared using chi-square analysis, alpha = 0.05. RESULTS: Two-hundred ninety-three of 308 (95%) EMTs attending the conference completed questionnaires. The median number of correct responses to the five knowledge questions was 1 (range 0-4). Thirty-three percent of the EMTs knew that other vehicles are required by law to yield while either approaching or being overtaken by an ambulance with warning lights and sirens; 2% knew that due regard for safety is the only requirement of an ambulance approaching a red light at an intersection; 14% knew that the minimum following distance behind an ambulance is one city block; and 28% knew that there is no speed limit on ambulances with warning lights and sirens. Respondents were more likely to score above the median if they had taken one or more emergency driver's education courses or had nine years or more of EMS experience. CONCLUSION: In this sample, EMT knowledge of basic traffic laws pertaining to ambulance operation is poor. Emergency driver's education courses and increased experience appear to be related to increased knowledge scores. Increased training for EMTs about traffic laws may improve the safe operation of ambulances.

Accidents, Traffic↗

Confirmation of a tetrahydrocannabinol metabolite in urine by gas chromatography.

A new method for confirming urinary 11-nor-delta 9-tetrahydrocannabinol-9-carboxylic acid, the major metabolite of tetrahydrocannabinol, has been developed. The metabolite is extracted, derivatized to the methyl ester, methyl ether, and analyzed on a gas chromatograph equipped with a flame ionization detector. In spiked urine specimens, metabolite concentrations as low as 20 ng/mL have been detected by this procedure. In a random sampling of urines, greater than 95% correlation was obtained between confirmation by this method and confirmation by gas chromatography/mass spectrometry in those specimens producing an immunological response greater than 75 ng/mL.

Chromatography, Gas↗