Good general practice.
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Attitude of Health Personnel↗
Biomedical subjects
J D Whitney
Publications and source records attributed to J D Whitney.
Standard rehydration fluids.
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Dehydration↗
Clinicians vs management.
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Administrative Personnel↗
Modifying perfusion, nutrition, and stress to promote wound healing in patients with acute wounds.
Tissue injury is common among patients in acute care settings. The subsequent response to injury, wound healing, follows an intricate but well-defined sequence that, under normal conditions, proceeds to satisfactory repair. However, because of the complexity of the healing response, several factors can intervene to impair normal healing. As a better understanding of how diverse factors influence healing is gained, the use of interventions that modulate these factors becomes possible and potentially beneficial. This article reviews knowledge of perfusion, nutrition, and stress as they relate to healing in patients experiencing acute wounds. Therapeutic implications based on current research are discussed.
Animals↗
The measurement of oxygen tension in tissue.
Delivery of oxygen to cells is critical to biochemical and metabolic processes and is particularly important during conditions of illness and recovery. However, accurate measurement of perfusion and tissue oxygen tension, determinants of cellular oxygen supply, has been problematic. Technologic advancements offer promise for the assessment of these significant variables. Instruments utilizing polarographic electrodes have been commonly used for the measurement of tissue oxygen tension. Recently, optical fluorescence has been employed to measure the partial pressure of oxygen. These predominant methods for determining tissue oxygen tension are described and applications for research are discussed.
Blood Gas Monitoring, Transcutaneous↗
The effects of activity and bed rest on tissue oxygen tension, perfusion, and plasma volume.
An experimental study with a crossover design was used to compare the effects of activity and bed rest on subcutaneous oxygen (PscO2), perfusion (BFsc), and plasma volume, and to explore the relationship of cardiovascular fitness to these variables. Fifteen healthy males were randomized to bed rest or activity and later completed the remaining protocol. Exercise prescription for the activity protocol and cardiovascular fitness were based on a treadmill performance test. Repeated measurements were made of subcutaneous oxygen and temperature using an optode in upper arm subcutaneous tonometers. Perfusion and PscO2 were greater during bed rest (p < .05). Post hoc analysis revealed a trend toward higher heart rates and diastolic blood pressure during the activity protocol. Change in plasma volume did not differ between protocols, and cardiovascular fitness was unrelated to PscO2 or BFsc. Findings suggest that in uninjured individuals, higher levels of activity intensity reduce oxygen levels and blood flow in peripheral tissues.
Adult↗